Comprehensive genomic characterization of long non-coding RNAs across human cancers X Yan, Z Hu, Y Feng, X Hu, J Yuan, SD Zhao, Y Zhang, L Yang, W Shan, ... Cancer cell 28 (4), 529-540, 2015 | 679 | 2015 |
A functional genomic approach identifies FAL1 as an oncogenic long noncoding RNA that associates with BMI1 and represses p21 expression in cancer X Hu, Y Feng, D Zhang, SD Zhao, Z Hu, J Greshock, Y Zhang, L Yang, ... Cancer cell 26 (3), 344-357, 2014 | 418 | 2014 |
Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer Y Zhang, Q He, Z Hu, Y Feng, L Fan, Z Tang, J Yuan, W Shan, C Li, X Hu, ... Nature structural & molecular biology 23 (6), 522-530, 2016 | 308 | 2016 |
Repression of BET activity sensitizes homologous recombination–proficient cancers to PARP inhibition L Yang, Y Zhang, W Shan, Z Hu, J Yuan, J Pi, Y Wang, L Fan, Z Tang, C Li, ... Science translational medicine 9 (400), eaal1645, 2017 | 240 | 2017 |
Integrated analysis of genetic ancestry and genomic alterations across cancers J Yuan, Z Hu, BA Mahal, SD Zhao, KH Kensler, J Pi, X Hu, Y Zhang, ... Cancer cell 34 (4), 549-560. e9, 2018 | 221 | 2018 |
MYC targeted long noncoding RNA DANCR promotes cancer in part by reducing p21 levels Y Lu, Z Hu, LS Mangala, ZE Stine, X Hu, D Jiang, Y Xiang, Y Zhang, ... Cancer research 78 (1), 64-74, 2018 | 111 | 2018 |
Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European genetic ancestry J Yuan, KH Kensler, Z Hu, Y Zhang, T Zhang, J Jiang, M Xu, Y Pan, ... PLoS genetics 16 (2), e1008641, 2020 | 99 | 2020 |
The Cancer Surfaceome Atlas integrates genomic, functional and drug response data to identify actionable targets Z Hu, J Yuan, M Long, J Jiang, Y Zhang, T Zhang, M Xu, Y Fan, JL Tanyi, ... Nature cancer 2 (12), 1406-1422, 2021 | 67 | 2021 |
Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment Z Hu, J Zhou, J Jiang, J Yuan, Y Zhang, X Wei, N Loo, Y Wang, Y Pan, ... Nature communications 10 (1), 733, 2019 | 56 | 2019 |
Knockdown of AGR2 induces cellular senescence in prostate cancer cells Z Hu, Y Gu, B Han, J Zhang, Z Li, K Tian, CYF Young, H Yuan Carcinogenesis 33 (6), 1178-1186, 2012 | 50 | 2012 |
Cyclin D1 silencing impairs DNA double strand break repair, sensitizes BRCA1 wildtype ovarian cancer cells to olaparib Q Zhong, Z Hu, Q Li, T Yi, J Li, H Yang Gynecologic Oncology 152 (1), 157-165, 2019 | 39 | 2019 |
Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer D Zhang, G Zhang, X Hu, L Wu, Y Feng, S He, Y Zhang, Z Hu, L Yang, ... Cancer research 77 (14), 3745-3757, 2017 | 37 | 2017 |
Systematic characterization of recurrent genomic alterations in cyclin-dependent kinases reveals potential therapeutic strategies for cancer treatment W Shan, J Yuan, Z Hu, J Jiang, Y Wang, N Loo, L Fan, Z Tang, T Zhang, ... Cell reports 32 (2), 2020 | 28 | 2020 |
Systematic illumination of druggable genes in cancer genomes J Jiang, J Yuan, Z Hu, Y Zhang, T Zhang, M Xu, M Long, Y Fan, JL Tanyi, ... Cell reports 38 (8), 2022 | 26 | 2022 |
Characterization of long non-coding RNA associated proteins by RNA-immunoprecipitation J Jiang, T Zhang, Y Pan, Z Hu, J Yuan, X Hu, L Zhang, Y Zhang Long Non-Coding RNAs: Methods and Protocols, 19-26, 2021 | 25 | 2021 |
Riccardin D induces cell death by activation of apoptosis and autophagy in osteosarcoma cells Y Wang, Y Ji, Z Hu, H Jiang, F Zhu, H Yuan, H Lou Toxicology in Vitro 27 (6), 1928-1936, 2013 | 21 | 2013 |
Targeting the lysosome by an aminomethylated Riccardin D triggers DNA damage through cathepsin B‐mediated degradation of BRCA1 Y Wang, H Niu, Z Hu, M Zhu, L Wang, L Han, L Qian, K Tian, H Yuan, ... Journal of Cellular and Molecular Medicine 23 (3), 1798-1812, 2019 | 19 | 2019 |
A novel derivative of riccardin D induces cell death through lysosomal rupture in vitro and inhibits tumor growth in vivo Y Wang, L Wang, Z Hu, Y Ji, Z Lin, H Yuan, M Ji, H Lou Cancer letters 329 (2), 207-216, 2013 | 19 | 2013 |
Induction of DNA damage and p21-dependent senescence by Riccardin D is a novel mechanism contributing to its growth suppression in prostate cancer cells in vitro and in vivo Z Hu, D Zhang, J Hao, K Tian, W Wang, H Lou, H Yuan Cancer chemotherapy and pharmacology 73, 397-407, 2014 | 17 | 2014 |
Bisbibenzyls, novel proteasome inhibitors, suppress androgen receptor transcriptional activity and expression accompanied by activation of autophagy in prostate cancer LNCaP cells Z Hu, D Zhang, D Wang, B Sun, A Safoor, CYF Young, H Lou, H Yuan Pharmaceutical biology 54 (2), 364-374, 2016 | 13 | 2016 |