متابعة
Sophia Khom
Sophia Khom
Assistant Professor, University of Vienna
بريد إلكتروني تم التحقق منه على univie.ac.at
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Valerenic acid potentiates and inhibits GABAA receptors: molecular mechanism and subunit specificity
S Khom, I Baburin, E Timin, A Hohaus, G Trauner, B Kopp, S Hering
Neuropharmacology 53 (1), 178-187, 2007
2382007
Pharmacological properties of GABAA receptors containing γ1 subunits
S Khom, I Baburin, EN Timin, A Hohaus, W Sieghart, S Hering
Molecular pharmacology 69 (2), 640-649, 2006
1282006
Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid
G Trauner, S Khom, I Baburin, B Benedek, S Hering, B Kopp
Planta Medica 74 (01), 19-24, 2008
1212008
Microglia control escalation of drinking in alcohol-dependent mice: genomic and synaptic drivers
AS Warden, SA Wolfe, S Khom, FP Varodayan, RR Patel, MQ Steinman, ...
Biological psychiatry 88 (12), 910-921, 2020
992020
The role of the central amygdala in alcohol dependence
M Roberto, D Kirson, S Khom
Cold Spring Harbor perspectives in medicine 11 (2), a039339, 2021
932021
Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala
BJ Tunstall, D Kirson, LJ Zallar, SA McConnell, JCM Vendruscolo, CP Ho, ...
PLoS biology 17 (4), e2006421, 2019
882019
The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission
V Chuong, M Farokhnia, S Khom, CL Pince, SK Elvig, R Vlkolinsky, ...
JCI insight 8 (12), e170671, 2023
812023
Valerenic acid derivatives as novel subunit‐selective GABAA receptor ligands –in vitro and in vivo characterization
S Khom, B Strommer, J Ramharter, T Schwarz, C Schwarzer, T Erker, ...
British journal of pharmacology 161 (1), 65-78, 2010
802010
Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives
A Schöffmann, L Wimmer, D Goldmann, S Khom, J Hintersteiner, ...
Journal of medicinal chemistry 57 (13), 5602-5619, 2014
622014
GABAA receptor modulation by piperine and a non-TRPV1 activating derivative
S Khom, B Strommer, A Schöffmann, J Hintersteiner, I Baburin, T Erker, ...
Biochemical pharmacology 85 (12), 1827-1836, 2013
612013
IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala
RR Patel, S Khom, MQ Steinman, FP Varodayan, WB Kiosses, ...
Brain, behavior, and immunity 75, 208-219, 2019
602019
Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal
AJ Roberts, S Khom, M Bajo, R Vlkolinsky, I Polis, C Cates-Gatto, ...
Brain, behavior, and immunity 82, 188-202, 2019
522019
Synthetic, Mechanistic, and Biological Interrogation of Ginkgo biloba Chemical Space En Route to (−)-Bilobalide
RM Demoret, MA Baker, M Ohtawa, S Chen, CC Lam, S Khom, M Roberto, ...
Journal of the American Chemical Society 142 (43), 18599-18618, 2020
512020
Bioactivity-Guided Isolation of GABAA Receptor Modulating Constituents from the Rhizomes of Actaea racemosa
SS Cicek, S Khom, B Taferner, S Hering, H Stuppner
Journal of natural products 73 (12), 2024-2028, 2010
512010
HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes
HJ Kim, I Baburin, S Khom, S Hering, M Hamburger
Planta medica 74 (05), 521-526, 2008
462008
Sex differences in acute alcohol sensitivity of naïve and alcohol dependent central amygdala GABA synapses
D Kirson, S Khom, L Rodriguez, SA Wolfe, FP Varodayan, PJ Gandhi, ...
Alcohol and Alcoholism 56 (5), 581-588, 2021
392021
CRF modulates glutamate transmission in the central amygdala of na´ ve and ethanol-dependent rats
FP Varodayan, D Correia, D Kirson, S Khom, CS Oleata, G Luu, ...
Neuropharmacology 125, 418-428, 2017
382017
Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site‐directed mutagenesis
D Luger, G Poli, M Wieder, M Stadler, S Ke, M Ernst, A Hohaus, T Linder, ...
British Journal of Pharmacology 172 (22), 5403-5413, 2015
372015
Identification and Characterization of GABAA Receptor Modulatory Diterpenes from Biota orientalis That Decrease Locomotor Activity in Mice
J Zaugg, S Khom, D Eigenmann, I Baburin, M Hamburger, S Hering
Journal of natural products 74 (8), 1764-1772, 2011
352011
The amygdala noradrenergic system is compromised with alcohol use disorder
FP Varodayan, RR Patel, A Matzeu, SA Wolfe, DE Curley, S Khom, ...
Biological psychiatry 91 (12), 1008-1018, 2022
322022
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مقالات 1–20