| Chimeric antigen receptor therapy for cancer DM Barrett, N Singh, DL Porter, SA Grupp, CH June Annual review of medicine 65 (1), 333-347, 2014 | 485 | 2014 |
| Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering MM Billingsley, N Singh, P Ravikumar, R Zhang, CH June, MJ Mitchell Nano letters 20 (3), 1578-1589, 2020 | 466 | 2020 |
| Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies N Singh, J Perazzelli, SA Grupp, DM Barrett Science translational medicine 8 (320), 320ra3-320ra3, 2016 | 312 | 2016 |
| An NK-like CAR T cell transition in CAR T cell dysfunction CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cell 184 (25), 6081-6100. e26, 2021 | 273 | 2021 |
| Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... Cancer discovery 10 (4), 552-567, 2020 | 254 | 2020 |
| Immunotherapy for ovarian cancer: what's next? LE Kandalaft, DJ Powell Jr, N Singh, G Coukos Journal of Clinical Oncology 29 (7), 925-933, 2011 | 177 | 2011 |
| Monocyte lineage–derived IL-6 does not affect chimeric antigen receptor T-cell function N Singh, TJ Hofmann, Z Gershenson, BL Levine, SA Grupp, DT Teachey, ... Cytotherapy 19 (7), 867-880, 2017 | 170 | 2017 |
| Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells N Singh, NV Frey, B Engels, DM Barrett, O Shestova, P Ravikumar, ... Nature medicine 27 (5), 842-850, 2021 | 140 | 2021 |
| Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy DM Barrett, N Singh, X Liu, S Jiang, CH June, SA Grupp, Y Zhao Cytotherapy 16 (5), 619-630, 2014 | 126 | 2014 |
| CAR T cell therapy in acute lymphoblastic leukemia and potential for chronic lymphocytic leukemia N Singh, NV Frey, SA Grupp, SL Maude Current treatment options in oncology 17, 1-11, 2016 | 87 | 2016 |
| Genome-editing technologies in adoptive T cell immunotherapy for cancer N Singh, J Shi, CH June, M Ruella Current hematologic malignancy reports 12, 522-529, 2017 | 86 | 2017 |
| Nature of tumor control by permanently and transiently modified GD2 chimeric antigen receptor T cells in xenograft models of neuroblastoma N Singh, X Liu, J Hulitt, S Jiang, CH June, SA Grupp, DM Barrett, Y Zhao Cancer immunology research 2 (11), 1059-1070, 2014 | 86 | 2014 |
| The emergence of immunomodulation: combinatorial immunochemotherapy opportunities for the next decade LE Kandalaft, N Singh, JB Liao, A Facciabene, JS Berek, DJ Powell Jr, ... Gynecologic oncology 116 (2), 222-233, 2010 | 50 | 2010 |
| Antigen glycosylation regulates efficacy of CAR T cells targeting CD19 A Heard, JH Landmann, AR Hansen, A Papadopolou, YS Hsu, ME Selli, ... Nature communications 13 (1), 3367, 2022 | 49 | 2022 |
| T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma N Singh, I Kulikovskaya, DM Barrett, G Binder-Scholl, B Jakobsen, ... Oncoimmunology 5 (1), e1040216, 2016 | 48 | 2016 |
| Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies S Zheng, E Gillespie, AS Naqvi, KE Hayer, Z Ang, M Torres-Diz, ... Blood cancer discovery 3 (2), 103-115, 2022 | 43 | 2022 |
| Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction ME Selli, JH Landmann, M Terekhova, J Lattin, A Heard, YS Hsu, ... Blood, The Journal of the American Society of Hematology 141 (26), 3153-3165, 2023 | 39 | 2023 |
| Mechanisms of resistance to CAR T cell therapies N Singh, E Orlando, J Xu, J Xu, Z Binder, MKA Collins, DM O’Rourke, ... Seminars in cancer biology 65, 91-98, 2020 | 38 | 2020 |
| Interleukin 6 is not made by chimeric antigen receptor T cells and does not impact their function DM Barrett, N Singh, TJ Hofmann, Z Gershenson, SA Grupp Blood 128 (22), 654, 2016 | 38 | 2016 |
| Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity J Yi, AT Miller, AS Archambault, AJ Jones, TR Bradstreet, S Bandla, ... Science immunology 7 (76), eabo0777, 2022 | 36 | 2022 |
Carl JuneUniversity of Pennsylvaniaبريد إلكتروني تم التحقق منه على upenn.edu
