متابعة
Bruce L Levine
Bruce L Levine
Barbara and Edward Netter Professor in Cancer Gene Therapy, Department of Pathology and Laboratory
بريد إلكتروني تم التحقق منه على pennmedicine.upenn.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Chimeric antigen receptor T cells for sustained remissions in leukemia
SL Maude, N Frey, PA Shaw, R Aplenc, DM Barrett, NJ Bunin, A Chew, ...
New England Journal of Medicine 371 (16), 1507-1517, 2014
61622014
Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia
SL Maude, TW Laetsch, J Buechner, S Rives, M Boyer, H Bittencourt, ...
New England Journal of Medicine 378 (5), 439-448, 2018
53342018
Chimeric antigen receptor–modified T cells in chronic lymphoid leukemia
DL Porter, BL Levine, M Kalos, A Bagg, CH June
New England Journal of Medicine 365 (8), 725-733, 2011
46862011
Chimeric antigen receptor–modified T cells for acute lymphoid leukemia
SA Grupp, M Kalos, D Barrett, R Aplenc, DL Porter, SR Rheingold, ...
New England Journal of Medicine 368 (16), 1509-1518, 2013
43042013
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
M Kalos, BL Levine, DL Porter, S Katz, SA Grupp, A Bagg, CH June
Science translational medicine 3 (95), 95ra73-95ra73, 2011
33032011
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
DL Porter, WT Hwang, NV Frey, SF Lacey, PA Shaw, AW Loren, A Bagg, ...
Science translational medicine 7 (303), 303ra139-303ra139, 2015
19732015
Chimeric antigen receptor T cells in refractory B-cell lymphomas
SJ Schuster, J Svoboda, EA Chong, SD Nasta, AR Mato, Ö Anak, ...
New England Journal of Medicine 377 (26), 2545-2554, 2017
19012017
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
P Tebas, D Stein, WW Tang, I Frank, SQ Wang, G Lee, SK Spratt, ...
New England Journal of Medicine 370 (10), 901-910, 2014
17922014
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...
Science translational medicine 9 (399), eaaa0984, 2017
17202017
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...
Nature medicine 24 (5), 563-571, 2018
15852018
CRISPR-engineered T cells in patients with refractory cancer
EA Stadtmauer, JA Fraietta, MM Davis, AD Cohen, KL Weber, E Lancaster, ...
Science 367 (6481), eaba7365, 2020
13442020
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
GP Linette, EA Stadtmauer, MV Maus, AP Rapoport, BL Levine, L Emery, ...
Blood, The Journal of the American Society of Hematology 122 (6), 863-871, 2013
13162013
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
CG Brunstein, JS Miller, Q Cao, DH McKenna, KL Hippen, J Curtsinger, ...
Blood, The Journal of the American Society of Hematology 117 (3), 1061-1070, 2011
12832011
Engineered T cells: the promise and challenges of cancer immunotherapy
AD Fesnak, CH June, BL Levine
Nature reviews cancer 16 (9), 566-581, 2016
12212016
Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
DT Teachey, SF Lacey, PA Shaw, JJ Melenhorst, SL Maude, N Frey, ...
Cancer discovery 6 (6), 664-679, 2016
10872016
NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
AP Rapoport, EA Stadtmauer, GK Binder-Scholl, O Goloubeva, DT Vogl, ...
Nature medicine 21 (8), 914-921, 2015
10442015
Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce antitumor activity in solid malignancies
GL Beatty, AR Haas, MV Maus, DA Torigian, MC Soulen, G Plesa, ...
Cancer immunology research 2 (2), 112-120, 2014
9742014
Global manufacturing of CAR T cell therapy
BL Levine, J Miskin, K Wonnacott, C Keir
Molecular therapy Methods & clinical development 4, 92-101, 2017
8362017
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
JA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ...
Nature 558 (7709), 307-312, 2018
8092018
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells
J Scholler, TL Brady, G Binder-Scholl, WT Hwang, G Plesa, KM Hege, ...
Science translational medicine 4 (132), 132ra53-132ra53, 2012
8082012
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مقالات 1–20