Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7 R Lu, T Yuan, Y Wang, T Zhang, Y Yuan, D Wu, M Zhou, Z He, Y Lu, ... EBioMedicine 36, 29-38, 2018 | 55 | 2018 |
Activation of PPAR-β/δ attenuates brain injury by suppressing inflammation and apoptosis in a collagenase-induced intracerebral hemorrhage mouse model X Tang, K Yan, Y Wang, Y Wang, H Chen, J Xu, Y Lu, X Wang, J Liang, ... Neurochemical Research 45, 837-850, 2020 | 33 | 2020 |
Generation of hyperlipidemic rabbit models using multiple sgRNAs targeted CRISPR/Cas9 gene editing system T Yuan, Y Zhong, Y Wang, T Zhang, R Lu, M Zhou, Y Lu, K Yan, Y Chen, ... Lipids in Health and Disease 18, 1-9, 2019 | 33 | 2019 |
Several circulating miRNAs related to hyperlipidemia and atherosclerotic cardiovascular diseases J Xu, Z Chen, Y Wang, X Wang, L Chen, T Yuan, X Tang, Y Lu, H Chen, ... Lipids in Health and Disease 18, 1-11, 2019 | 29 | 2019 |
CRISPR/Cas9-mediated knockout of APOC3 stabilizes plasma lipids and inhibits atherosclerosis in rabbits Y Zha, Y Lu, T Zhang, K Yan, W Zhuang, J Liang, Y Cheng, Y Wang Lipids in health and disease 20 (1), 180, 2021 | 28 | 2021 |
Prime editing optimized RTT permits the correction of the c. 8713C> T mutation in DMD gene CH Mbakam, J Rousseau, Y Lu, A Bigot, K Mamchaoui, V Mouly, ... Molecular Therapy Nucleic Acids 30, 272-285, 2022 | 22 | 2022 |
‘Double-muscling’and pelvic tilt phenomena in rabbits with the cystine-knot motif deficiency of myostatin on exon 3 T Zhang, Y Lu, S Song, R Lu, M Zhou, Z He, T Yuan, K Yan, Y Cheng Bioscience Reports 39 (5), BSR20190207, 2019 | 19 | 2019 |
CRISPR-Cas9 delivery strategies with engineered extracellular vesicles Y Lu, K Godbout, G Lamothe, JP Tremblay Molecular Therapy-Nucleic Acids 34, 2023 | 17 | 2023 |
Accurately cleavable goat β-lactoglobulin signal peptide efficiently guided translation of a recombinant human plasminogen activator in transgenic rabbit mammary gland R Lu, T Zhang, S Song, M Zhou, L Jiang, Z He, Y Yuan, T Yuan, Y Lu, ... Bioscience reports 39 (6), BSR20190596, 2019 | 15 | 2019 |
Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases Y Lu, C Happi Mbakam, B Song, E Bendavid, JP Tremblay Frontiers in Genome Editing 4, 892769, 2022 | 12 | 2022 |
The goat β-casein/CMV chimeric promoter drives the expression of hLF in transgenic goats produced by cell transgene microinjection T Zhang, Y Yuan, R Lu, S Xu, M Zhou, T Yuan, Y Lu, K Yan, Y Cheng International Journal of Molecular Medicine 44 (6), 2057-2064, 2019 | 8 | 2019 |
Prime editing strategies to mediate exon skipping in DMD gene C Happi Mbakam, J Roustant, J Rousseau, P Yameogo, Y Lu, A Bigot, ... Frontiers in Medicine 10, 1128557, 2023 | 7 | 2023 |
重组人 SOD1/3 转基因山羊的制备及表达产物的检测 周敏雅, 陆睿, 张婷, 袁婷婷, 卢瑶瑶, 严坤宁, 袁玉国, 成勇 生物技术通报 35 (5), 85-92, 2019 | 3 | 2019 |
HMGB1 与动脉粥样硬化相关疾病的研究进展 钟港, 孙雨婷, 王梦恬, 袁婷婷, 卢瑶瑶, 冯瑞玲, 梁景岩 医学综述 25 (10), 1873-1878, 2019 | 1 | 2019 |
利用 CRISPR/Cas9 技术制备 ApoE-/-兔 袁婷婷, 周敏雅, 卢瑶瑶, 陆睿, 张婷, 孙雨婷, 钟港, 王梦恬, 黄俊杰, ... 中国动脉硬化杂志 26 (7), 658-665, 2018 | 1 | 2018 |
Emerging Perspectives on Prime Editor Delivery to the Brain E BenDavid, S Ramezanian, Y Lu, J Rousseau, A Schroeder, M Lavertu, ... Pharmaceuticals 17 (6), 763, 2024 | | 2024 |
The Advancement and Applications of Prime Editing Y Lu, C Bouchard, N Soucy, A Siddika, G Lamothe, K Godbout, ... | | 2024 |
运用 CRISPR/Cas9 基因编辑技术制备载脂蛋白 C3 基因敲除兔模型的相关研究 卢瑶瑶 扬州大学, 2020 | | 2020 |
Preparation of Recombinant Human SOD1/3 Transgenic Goat and Detection of Expressed Products M ZHOU, R LU, T ZHANG, T YUAN, Y LU, K YAN, Y YUAN, Y CHENG Biotechnology Bulletin 35 (5), 85, 2019 | | 2019 |
动脉粥样硬化相关 miRNAs 的概述 田嘉珉, 徐将, 卢瑶瑶, 梁景岩 中国社区医师 29, 2019 | | 2019 |