متابعة
Lekha Mikkilineni
Lekha Mikkilineni
Assistant Professor, BMT & Cell Therapy, Stanford University
بريد إلكتروني تم التحقق منه على stanford.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
T cells genetically modified to express an anti–B-cell maturation antigen chimeric antigen receptor cause remissions of poor-prognosis relapsed multiple myeloma
JN Brudno, I Maric, SD Hartman, JJ Rose, M Wang, N Lam, ...
Journal of Clinical Oncology 36 (22), 2267, 2018
8192018
Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma
JN Brudno, N Lam, D Vanasse, Y Shen, JJ Rose, J Rossi, A Xue, A Bot, ...
Nature medicine 26 (2), 270-280, 2020
2802020
CAR T cell therapies for patients with multiple myeloma
L Mikkilineni, JN Kochenderfer
Nature reviews Clinical oncology 18 (2), 71-84, 2021
2542021
Chimeric antigen receptor T-cell therapies for multiple myeloma
L Mikkilineni, JN Kochenderfer
Blood, The Journal of the American Society of Hematology 130 (24), 2594-2602, 2017
2452017
The Bethesda handbook of clinical oncology
J Abraham, JL Gulley
Lippincott Williams & Wilkins, 2022
1652022
A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1–3 inhibitor, cediranib, in recurrent women’s cancers with …
AS Zimmer, E Nichols, A Cimino-Mathews, C Peer, L Cao, MJ Lee, ...
Journal for immunotherapy of cancer 7, 1-8, 2019
1062019
MCT1 in invasive ductal carcinoma: monocarboxylate metabolism and aggressive breast cancer
JM Johnson, P Cotzia, R Fratamico, L Mikkilineni, J Chen, D Colombo, ...
Frontiers in cell and developmental biology 5, 27, 2017
712017
Hodgkin lymphoma: A complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment
L Mikkilineni, D Whitaker-Menezes, M Domingo-Vidal, J Sprandio, ...
Seminars in oncology 44 (3), 218-225, 2017
592017
Infectious complications of CAR T-cell therapy across novel antigen targets in the first 30 days
L Mikkilineni, B Yates, SM Steinberg, SA Shahani, JC Molina, T Palmore, ...
Blood Advances 5 (23), 5312-5322, 2021
472021
T cells expressing an anti-B-cell maturation antigen (BCMA) chimeric antigen receptor with a fully-human heavy-chain-only antigen recognition domain induce remissions in …
L Mikkilineni, EE Manasanch, N Lam, D Vanasse, JN Brudno, I Maric, ...
Blood 134, 3230, 2019
362019
The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes
AJ Faruqi, JA Ligon, P Borgman, SM Steinberg, T Foley, L Little, ...
Blood Advances 6 (23), 6040-6050, 2022
332022
Deep and durable remissions of relapsed multiple myeloma on a first-in-humans clinical trial of T cells expressing an anti-B-cell maturation antigen (BCMA) chimeric antigen …
L Mikkilineni, EE Manasanch, D Vanasse, JN Brudno, J Mann, R Sherry, ...
Blood 136, 50-51, 2020
182020
Treatment of patients with T cells expressing a fully-human anti-BCMA CAR with a heavy-chain antigen-recognition domain Caused high rates of sustained complete responses and …
L Mikkilineni, EE Manasanch, D Natrakul, JN Brudno, J Mann, SL Goff, ...
Blood 138, 3837, 2021
112021
Low levels of neurologic toxicity with retained anti-lymphoma activity in a phase I clinical trial of T cells expressing a novel anti-CD19 CAR
J Brudno, S Hartman, N Lam, DF Stroncek, JM Rossi, Y Shen, A Xue, ...
Blood 132, 697, 2018
112018
Infectious complications associated with CAR T-cell therapy
L Mikkilineni, S Shahani, B Yates, SM Steinberg, T Palmore, ...
Blood 134, 4449, 2019
102019
Transient responses and significant toxicities of anti-CD30 CAR T cells for CD30+ lymphomas: results of a phase 1 trial
JN Brudno, DA Natrakul, J Karrs, N Patel, R Maass-Moreno, MA Ahlman, ...
Blood Advances 8 (3), 802-814, 2024
92024
Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain
L Mikkilineni, DA Natrakul, N Lam, EE Manasanch, J Mann, KA Weissler, ...
Molecular Therapy 32 (2), 503-526, 2024
92024
Clinical anti-lymphoma activity and toxicity of T cells expressing a novel anti-CD19 chimeric antigen receptor with fully-human variable regions.
JN Brudno, SD Hartman, S Pittaluga, D Stroncek, N Lam, JA Kanakry, ...
Journal of Clinical Oncology 36 (15_suppl), 3052-3052, 2018
82018
T Cells Expressing a Fully-Human Anti-BCMA Chimeric Antigen Receptor with a Heavy-Chain-Only Antigen-Recognition Domain Exhibit Rapid and Durable Activity Against Multiple Myeloma
L Mikkilineni, EE Manasanch, D Natrakul, K Weissler, JN Brudno, J Mann, ...
Blood 140 (Supplement 1), 7433-7434, 2022
72022
Integrating Immune Therapies for the Treatment of Multiple Myeloma
L Mikkilineni, S Sidana
Journal of the National Comprehensive Cancer Network 21 (12), 1303-1311, 2023
52023
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مقالات 1–20