| The canonical Notch signaling pathway: unfolding the activation mechanism R Kopan, MXG Ilagan Cell 137 (2), 216-233, 2009 | 4207 | 2009 |
| γ-Secretase: proteasome of the membrane? R Kopan, MXG Ilagan Nature reviews Molecular cell biology 5 (6), 499-504, 2004 | 721 | 2004 |
| Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2 JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ... Cell host & microbe 28 (3), 475-485. e5, 2020 | 415 | 2020 |
| A presenilin dimer at the core of the γ-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis EH Schroeter, MXG Ilagan, AL Brunkan, S Hecimovic, Y Li, M Xu, ... Proceedings of the National Academy of Sciences 100 (22), 13075-13080, 2003 | 261 | 2003 |
| SnapShot: notch signaling pathway MXG Ilagan, R Kopan Cell 128 (6), 1246. e1-1246. e2, 2007 | 183 | 2007 |
| Analysis of Notch function in presomitic mesoderm suggests a γ-secretase-independent role for presenilins in somite differentiation SS Huppert, MXG Ilagan, B De Strooper, R Kopan Developmental cell 8 (5), 677-688, 2005 | 173 | 2005 |
| Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes KL Arnett, M Hass, DG McArthur, MXG Ilagan, JC Aster, R Kopan, ... Nature structural & molecular biology 17 (11), 1312-1317, 2010 | 144 | 2010 |
| γ-Secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin G Zhao, Z Liu, MXG Ilagan, R Kopan Journal of Neuroscience 30 (5), 1648-1656, 2010 | 131 | 2010 |
| Quantitative dissection of the Notch: CSL interaction: insights into the Notch-mediated transcriptional switch OY Lubman, MXG Ilagan, R Kopan, D Barrick Journal of molecular biology 365 (3), 577-589, 2007 | 125 | 2007 |
| The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development Z Liu, S Chen, S Boyle, Y Zhu, A Zhang, DR Piwnica-Worms, MXG Ilagan, ... Developmental cell 25 (6), 585-598, 2013 | 111 | 2013 |
| Real-time imaging of notch activation with a luciferase complementation-based reporter MXG Ilagan, S Lim, M Fulbright, D Piwnica-Worms, R Kopan Science signaling 4 (181), rs7-rs7, 2011 | 103 | 2011 |
| An overview of notch signaling in adult tissue renewal and maintenance C Sato, G Zhao, M Xenia G. Ilagan Current Alzheimer Research 9 (2), 227-240, 2012 | 77 | 2012 |
| Structural analysis uncovers lipid-binding properties of Notch ligands CR Chillakuri, D Sheppard, MXG Ilagan, LR Holt, F Abbott, S Liang, ... Cell reports 5 (4), 861-867, 2013 | 74 | 2013 |
| RNF4-dependent oncogene activation by protein stabilization JJ Thomas, M Abed, J Heuberger, R Novak, Y Zohar, APB Lopez, ... Cell reports 16 (12), 3388-3400, 2016 | 68 | 2016 |
| Thermodynamic analysis of the CSL· notch interaction: Distribution of binding energy of the notch RAM region to the CSL β-trefoil domain and the mode of competition with the … SE Johnson, MXG Ilagan, R Kopan, D Barrick Journal of Biological Chemistry 285 (9), 6681-6692, 2010 | 51 | 2010 |
| Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor KS Yang, MXG Ilagan, D Piwnica-Worms, LJ Pike Journal of Biological Chemistry 284 (12), 7474-7482, 2009 | 50 | 2009 |
| Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV-light MXU Garcia, C Foote, S Van Es, PN Devreotes, S Alexander, H Alexander Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1492 (2-3 …, 2000 | 46 | 2000 |
| Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice WT Hodges, C Jarasvaraparn, D Ferguson, K Griffett, LE Gill, Y Chen, ... Journal of Biological Chemistry 298 (2), 2022 | 33 | 2022 |
| Differential developmental expression of the repB and repD Xeroderma pigmentosum related DNA helicase genes from Dictyostelium discoideum SK Lee, SL Yu, MX Garcia, H Alexander, S Alexander Nucleic acids research 25 (12), 2365-2374, 1997 | 30 | 1997 |
| A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants N Pishesha, TJ Harmand, PW Rothlauf, P Praest, RK Alexander, ... Proceedings of the National Academy of Sciences 118 (44), e2116147118, 2021 | 28 | 2021 |
