متابعة
Benjamin Nacev
Benjamin Nacev
University of Pittsburgh School of Medicine
بريد إلكتروني تم التحقق منه على upmc.edu - الصفحة الرئيسية
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
The expanding landscape of ‘oncohistone’mutations in human cancers‏
BA Nacev, L Feng, JD Bagert, AE Lemiesz, JJ Gao, AA Soshnev, ...‏
Nature 567 (7749), 473-478, 2019‏
3612019
Protein N-Terminal Processing: Substrate Specificity of Escherichia coli and Human Methionine Aminopeptidases‏
Q Xiao, F Zhang, BA Nacev, JO Liu, D Pei‏
Biochemistry 49 (26), 5588-5599, 2010‏
2162010
The epigenomics of sarcoma‏
BA Nacev, KB Jones, AM Intlekofer, JSE Yu, CD Allis, WD Tap, M Ladanyi, ...‏
Nature Reviews Cancer 20 (10), 608-623, 2020‏
1892020
The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells‏
BA Nacev, P Grassi, A Dell, SM Haslam, JO Liu‏
Journal of Biological Chemistry 286 (51), 44045-44056, 2011‏
1482011
Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets‏
BA Nacev, F Sanchez-Vega, SA Smith, CR Antonescu, E Rosenbaum, ...‏
Nature communications 13 (1), 3405, 2022‏
1342022
Effect of nitroxoline on angiogenesis and growth of human bladder cancer‏
JS Shim, Y Matsui, S Bhat, BA Nacev, J Xu, HC Bhang, S Dhara, KC Han, ...‏
Journal of the National Cancer Institute 102 (24), 1855-1873, 2010‏
1302010
Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of mTOR signaling and angiogenesis‏
SA Head, WQ Shi, EJ Yang, BA Nacev, SY Hong, KK Pasunooti, RJ Li, ...‏
ACS chemical biology 12 (1), 174-182, 2017‏
772017
Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1‏
B Ouyang, JA Knauf, K Ain, B Nacev, JA Fagin‏
Clinical endocrinology 56 (3), 341-350, 2002‏
772002
Oncohistone mutations enhance chromatin remodeling and alter cell fates‏
JD Bagert, MM Mitchener, AL Patriotis, BE Dul, F Wojcik, BA Nacev, ...‏
Nature chemical biology 17 (4), 403-411, 2021‏
762021
Itraconazole side chain analogues: structure–activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 …‏
W Shi, BA Nacev, BT Aftab, S Head, CM Rudin, JO Liu‏
Journal of medicinal chemistry 54 (20), 7363-7374, 2011‏
752011
High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S)‏
BAP Wilson, H Wang, BA Nacev, RC Mease, JO Liu, MG Pomper, ...‏
Molecular cancer therapeutics 10 (5), 825-838, 2011‏
642011
Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole‏
W Shi, BA Nacev, S Bhat, JO Liu‏
ACS medicinal chemistry letters 1 (4), 155-159, 2010‏
522010
Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole‏
BA Nacev, JO Liu‏
PloS one 6 (9), e24793, 2011‏
422011
Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma‏
SP D’Angelo, AL Richards, AP Conley, HJ Woo, MA Dickson, M Gounder, ...‏
Nature communications 13 (1), 3477, 2022‏
372022
Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center‏
E Rosenbaum, CR Antonescu, S Smith, M Bradic, D Kashani, ...‏
Journal for immunotherapy of cancer 10 (4), e004149, 2022‏
362022
A phase II study of epacadostat and pembrolizumab in patients with advanced sarcoma‏
CM Kelly, LX Qin, KA Whiting, AL Richards, V Avutu, JE Chan, P Chi, ...‏
Clinical Cancer Research 29 (11), 2043-2051, 2023‏
35*2023
Clinical Outcome of Leiomyosarcomas With Somatic Alteration in Homologous Recombination Pathway Genes‏
E Rosenbaum, P Jonsson, K Seier, LX Qin, P Chi, M Dickson, M Gounder, ...‏
JCO precision oncology 4, 1350-1360, 2020‏
322020
A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog‏
BA Nacev, WK Low, Z Huang, TT Su, Z Su, H Alkuraya, D Kasuga, W Sun, ...‏
The Journal of Pharmacology and Experimental Therapeutics 338 (2), 466-475, 2011‏
262011
Phase II trial of imatinib plus binimetinib in patients with treatment-naive advanced gastrointestinal stromal tumor‏
P Chi, LX Qin, B Nguyen, CM Kelly, SP D'Angelo, MA Dickson, ...‏
Journal of Clinical Oncology 40 (9), 997-1008, 2022‏
212022
Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells‏
F Zhang, S Bhat, SB Gabelli, X Chen, MS Miller, BA Nacev, YL Cheng, ...‏
Journal of medicinal chemistry 56 (10), 3996-4016, 2013‏
202013
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مقالات 1–20