| The tumor microenvironment represses T cell mitochondrial biogenesis to drive intratumoral T cell metabolic insufficiency and dysfunction NE Scharping, AV Menk, RS Moreci, RD Whetstone, RE Dadey, ... Immunity 45 (2), 374-388, 2016 | 919 | 2016 |
| Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion NE Scharping, DB Rivadeneira, AV Menk, PDA Vignali, BR Ford, ... Nature immunology 22 (2), 205-215, 2021 | 577 | 2021 |
| Efficacy of PD-1 blockade is potentiated by metformin-induced reduction of tumor hypoxia NE Scharping, AV Menk, RD Whetstone, X Zeng, GM Delgoffe Cancer immunology research 5 (1), 9-16, 2017 | 486 | 2017 |
| Early TCR signaling induces rapid aerobic glycolysis enabling distinct acute T cell effector functions AV Menk, NE Scharping, RS Moreci, X Zeng, C Guy, S Salvatore, H Bae, ... Cell reports 22 (6), 1509-1521, 2018 | 465 | 2018 |
| CD8+ T cell metabolism in infection and cancer M Reina-Campos, NE Scharping, AW Goldrath Nature Reviews Immunology 21 (11), 718-738, 2021 | 403 | 2021 |
| 4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses AV Menk, NE Scharping, DB Rivadeneira, MJ Calderon, MLJ Watson, ... Journal of experimental medicine 215 (4), 1091-1100, 2018 | 258 | 2018 |
| B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6 SW Jackson, HM Jacobs, T Arkatkar, EM Dam, NE Scharping, ... Journal of Experimental Medicine 213 (5), 733-750, 2016 | 216 | 2016 |
| Opposing impact of B cell–intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation SW Jackson, NE Scharping, NS Kolhatkar, S Khim, MA Schwartz, QZ Li, ... The Journal of Immunology 192 (10), 4525-4532, 2014 | 166 | 2014 |
| Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity PDA Vignali, K DePeaux, MLJ Watson, C Ye, BR Ford, K Lontos, ... Nature immunology 24 (2), 267-279, 2023 | 154 | 2023 |
| Roles of inflammatory caspases during processing of zebrafish interleukin-1β in Francisella noatunensis infection LN Vojtech, N Scharping, JC Woodson, JD Hansen Infection and immunity 80 (8), 2878-2885, 2012 | 134 | 2012 |
| Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells I Liikanen, C Lauhan, S Quon, K Omilusik, AT Phan, LB Bartrolí, A Ferry, ... The Journal of clinical investigation 131 (7), 2021 | 121 | 2021 |
| Tumor microenvironment metabolism: a new checkpoint for anti-tumor immunity NE Scharping, GM Delgoffe Vaccines 4 (4), 46, 2016 | 104 | 2016 |
| IRF1 inhibits antitumor immunity through the upregulation of PD-L1 in the tumor cell L Shao, W Hou, NE Scharping, FP Vendetti, R Srivastava, CN Roy, ... Cancer immunology research 7 (8), 1258-1266, 2019 | 78 | 2019 |
| Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells BR Ford, PDA Vignali, NL Rittenhouse, NE Scharping, R Peralta, ... Science immunology 7 (74), eabj9123, 2022 | 67 | 2022 |
| Efficacy of PD-1 blockade is potentiated by metformin-induced reduction of tumor hypoxia. Cancer Immunol Res.(2017) 5: 9–16. doi: 10.1158/2326-6066 NE Scharping, AV Menk, RD Whetstone, X Zeng, GM Delgoffe CIR-16-0103, 0 | 57 | |
| Cutting edge: BAFF promotes autoantibody production via TACI-dependent activation of transitional B cells HM Jacobs, CD Thouvenel, S Leach, T Arkatkar, G Metzler, NE Scharping, ... The Journal of Immunology 196 (9), 3525-3531, 2016 | 56 | 2016 |
| Cutting edge: BAFF overexpression reduces atherosclerosis via TACI-dependent B cell activation SW Jackson, NE Scharping, HM Jacobs, S Wang, A Chait, DJ Rawlings The Journal of Immunology 197 (12), 4529-4534, 2016 | 43 | 2016 |
| Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection JJ Milner, C Toma, S Quon, K Omilusik, NE Scharping, A Dey, ... Journal of Experimental Medicine 218 (8), 2021 | 29 | 2021 |
| B‐cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott–Aldrich syndrome NS Kolhatkar, NE Scharping, JM Sullivan, HM Jacobs, MA Schwartz, ... European journal of immunology 45 (10), 2773-2779, 2015 | 24 | 2015 |
| 31st annual meeting and associated programs of the society for immunotherapy of cancer (Sitc 2016): Part two: National harbor, md, USA. 9-13 November 2016 C Ager, M Reilley, C Nicholas, T Bartkowiak, A Jaiswal, M Curran, ... Journal for ImmunoTherapy of Cancer 4, 107-221, 2016 | 13 | 2016 |
