A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function M Lyon, P Li, JJ Ferreira, RM Lazarenko, SV Kharade, M Kramer, ... Proceedings of the National Academy of Sciences 120 (4), e2212338120, 2023 | 29 | 2023 |
The pharmacokinetics of racemic MDPV and its (R) and (S) enantiomers in female and male rats MD Hambuchen, HP Hendrickson, MG Gunnell, SJ McClenahan, ... Drug and alcohol dependence 179, 347-354, 2017 | 27 | 2017 |
Beta1-Adrenergic Receptor-Mediated Dilation of Rat Cerebral Artery Requires Shaker-Type KV1 Channels on PSD95 Scaffold CL Moore, SJ McClenahan, HM Hanvey, DS Jang, PL Nelson, BK Joseph, ... Journal of Cerebral Blood Flow & Metabolism 35 (9), 1537-1546, 2015 | 21 | 2015 |
Cardiovascular effects of 3, 4-methylenedioxypyrovalerone (MDPV) in male and female Sprague-Dawley rats SJ McClenahan, MD Hambuchen, CM Simecka, MG Gunnell, ... Drug and alcohol dependence 195, 140-147, 2019 | 18 | 2019 |
VU6036720: the first potent and selective in vitro inhibitor of heteromeric Kir4. 1/5.1 inward rectifier potassium channels SJ McClenahan, CN Kent, SV Kharade, E Isaeva, JC Williams, C Han, ... Molecular Pharmacology 101 (5), 357-370, 2022 | 11 | 2022 |
Metoprolol impairs β1-adrenergic receptor-mediated vasodilation in rat cerebral arteries: implications for β-blocker therapy CL Moore, DS Henry, SJ McClenahan, KK Ball, NJ Rusch, SW Rhee The Journal of Pharmacology and Experimental Therapeutics 376 (1), 127-135, 2021 | 8 | 2021 |
BK Channels in Rat and Human Pulmonary Smooth Muscle Cells are BKα-β1 Functional Complexes Lacking the Oxygen-Sensitive Stress Axis Regulated Exon … ND Detweiler, L Song, SJ McClenahan, RJ Versluis, SV Kharade, ... Pulmonary circulation 6 (4), 563-575, 2016 | 8 | 2016 |
Pharmacokinetics of α-Pyrrolidinovalerophenone in Male Rats with and without Vaccination with an α-Pyrrolidinovalerophenone Vaccine S McClenahan, M Gunnell, M Owens Journal of Pharmacy & Pharmaceutical Sciences 24, 267-276, 2021 | 6 | 2021 |
Design, synthesis and biological evaluation of a bi-specific vaccine against α-pyrrolidinovalerophenone (α-PVP) and 3, 4-methylenedioxypyrovalerone (MDPV) in rats SJ McClenahan, CM Kormos, M Gunnell, MD Hambuchen, P Lamb, ... Vaccine 38 (2), 336-344, 2020 | 5 | 2020 |
Core elements of national policy for digital health technology evidence and access M Coder, L McBride, S McClenahan NPJ Digital Medicine 7 (1), 212, 2024 | 4 | 2024 |
Active vaccination reduces reinforcing effects of MDPV in male Sprague-Dawley rats trained to self-administer cocaine SJ McClenahan, MG Gunnell, SM Owens, WE Fantegrossi Psychopharmacology 237, 2613-2620, 2020 | 4 | 2020 |
Discovery and characterization of VU0542270, the first selective inhibitor of vascular Kir6. 1/SUR2B KATP channels K Li, SJ McClenahan, C Han, JD Bungard, U Rathnayake, O Boutaud, ... Molecular Pharmacology 105 (3), 202-212, 2024 | 3 | 2024 |
Development of novel therapeutics for treating edema and SeSAME/EAST syndrome targeting heteromeric Kir4. 1/5.1 potassium channels SJ McClenahan, SV Kharade, JS Denton The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
Pharmacological Rescue of Human Disease Mutations in KCNJ10 and KCNJ16 by Novel Kir4. 1/5.1 Potentiator, VU0493206 S McClenahan, D Lee, J Denton The Journal of Pharmacology and Experimental Therapeutics 385, 365, 2023 | | 2023 |
Development of the first vascular-specific KATP channel inhibitor for the treatment of patent ductus arteriosus in newborns K Li, SJ McClenahan, EL Shelton, CW Lindsley, J Denton The Journal of Pharmacology and Experimental Therapeutics 385, 158, 2023 | | 2023 |
Discovery and Characterization of VU0493206, the First Small-Molecule Activator of Kir4. 1/Kir5. 1 Channels: TH-PO325 SJ Mcclenahan, E Isaeva, CA Klemens, A Staruschenko, JS Denton Journal of the American Society of Nephrology 33 (11S), 138, 2022 | | 2022 |
Discovery and Characterization of Small-Molecule Potentiators of Kir4. 1/5.1: PO2156 SJ Mcclenahan, JS Denton Journal of the American Society of Nephrology 31 (10S), 660, 2020 | | 2020 |
Pharmacokinetic, Cardiovascular and Locomotor Effects of alpha‐Pyrrolidinopentiophenone (alpha‐PVP) in Male Sprague Dawley Rats after Active Vaccination SJ McClenahan, CM Kormos, S Mu, MD Hambuchen, IF Carroll, ... The FASEB Journal 33 (S1), 664.15-664.15, 2019 | | 2019 |
Development and Preclinical Testing of a 3, 4-Methylenedioxypyrovalerone-like Vaccine in Rats S McClenahan University of Arkansas for Medical Sciences, 2019 | | 2019 |
Organ Distribution and Clearance of (3, 4)‐Methylenedioxypyrovalerone (MDPV) Enantiomers in Female and Male Rats after Intravenous Administration of Racemic MDPV MD Hambuchen, HP Hendrickson, MG Gunnell, SJ McClenahan, ... The FASEB Journal 32, 681.4-681.4, 2018 | | 2018 |