Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy FH Yu, M Mantegazza, RE Westenbroek, CA Robbins, F Kalume, ... Nature neuroscience 9 (9), 1142-1149, 2006 | 1278 | 2006 |
Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders M Mantegazza, G Curia, G Biagini, DS Ragsdale, M Avoli The Lancet Neurology 9 (4), 413-424, 2010 | 535 | 2010 |
Identification of an Nav1. 1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures M Mantegazza, A Gambardella, R Rusconi, E Schiavon, F Annesi, ... Proceedings of the National Academy of Sciences 102 (50), 18177-18182, 2005 | 265 | 2005 |
Inhibition of transient and persistent Na+ current fractions by the new anticonvulsant topiramate S Taverna, G Sancini, M Mantegazza, S Franceschetti, G Avanzini Journal of Pharmacology and Experimental Therapeutics 288 (3), 960-968, 1999 | 223 | 1999 |
Impaired action potential initiation in GABAergic interneurons causes hyperexcitable networks in an epileptic mouse model carrying a human NaV1. 1 mutation UBS Hedrich, C Liautard, D Kirschenbaum, M Pofahl, J Lavigne, Y Liu, ... Journal of Neuroscience 34 (45), 14874-14889, 2014 | 172 | 2014 |
Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice C Vicidomini, L Ponzoni, D Lim, MJ Schmeisser, D Reim, N Morello, ... Molecular psychiatry 22 (5), 689-702, 2017 | 168 | 2017 |
Role of the C-terminal domain in inactivation of brain and cardiac sodium channels M Mantegazza, FH Yu, WA Catterall, T Scheuer Proceedings of the National Academy of Sciences 98 (26), 15348-15353, 2001 | 162 | 2001 |
Action potentials recorded with patch-clamp amplifiers: are they genuine? J Magistretri, M Mantegazza, E Guatteo, E Wanke Trends in neurosciences 19 (12), 530-534, 1996 | 161 | 1996 |
Effects in neocortical neurons of mutations of the Nav1. 2 Na+ channel causing benign familial neonatal-infantile seizures P Scalmani, R Rusconi, E Armatura, F Zara, G Avanzini, S Franceschetti, ... Journal of neuroscience 26 (40), 10100-10109, 2006 | 152 | 2006 |
Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1. 1 (SCN1A) Na+ channel S Cestèle, P Scalmani, R Rusconi, B Terragni, S Franceschetti, ... Journal of Neuroscience 28 (29), 7273-7283, 2008 | 148 | 2008 |
Modulatory proteins can rescue a trafficking defective epileptogenic Nav1. 1 Na+ channel mutant R Rusconi, P Scalmani, RR Cassulini, G Giunti, A Gambardella, ... Journal of Neuroscience 27 (41), 11037-11046, 2007 | 137 | 2007 |
Molecular determinants for modulation of persistent sodium current by G-protein βγ subunits M Mantegazza, HY Frank, AJ Powell, JJ Clare, WA Catterall, T Scheuer Journal of Neuroscience 25 (13), 3341-3349, 2005 | 130 | 2005 |
Action potential initiation in neocortical inhibitory interneurons T Li, C Tian, P Scalmani, C Frassoni, M Mantegazza, Y Wang, M Yang, ... PLoS biology 12 (9), e1001944, 2014 | 129 | 2014 |
Nonfunctional NaV1. 1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects S Cestèle, E Schiavon, R Rusconi, S Franceschetti, M Mantegazza Proceedings of the National Academy of Sciences 110 (43), 17546-17551, 2013 | 117 | 2013 |
Anemone toxin (ATX II)‐induced increase in persistent sodium current: effects on the firing properties of rat neocortical pyramidal neurones M Mantegazza, S Franceschetti, G Avanzini The Journal of physiology 507 (1), 105-116, 1998 | 116 | 1998 |
A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation B Tang, K Dutt, L Papale, R Rusconi, A Shankar, J Hunter, S Tufik, ... Neurobiology of disease 35 (1), 91-102, 2009 | 114 | 2009 |
Valproate selectively reduces the persistent fraction of Na+ current in neocortical neurons S Taverna, M Mantegazza, S Franceschetti, G Avanzini Epilepsy research 32 (1-2), 304-308, 1998 | 114 | 1998 |
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ... The Lancet Neurology 17 (8), 699-708, 2018 | 95 | 2018 |
The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications A Brunklaus, T Brünger, T Feng, C Fons, A Lehikoinen, E Panagiotakaki, ... Brain 145 (11), 3816-3831, 2022 | 90 | 2022 |
Pathophysiological mechanisms of migraine and epilepsy: similarities and differences M Mantegazza, S Cestèle Neuroscience letters 667, 92-102, 2018 | 90 | 2018 |