Role of neuroinflammation in neurodegeneration development W Zhang, D Xiao, Q Mao, H Xia Signal transduction and targeted therapy 8 (1), 267, 2023 | 501 | 2023 |
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice G Casella, J Rasouli, A Boehm, W Zhang, D Xiao, LLW Ishikawa, ... Science translational medicine 12 (568), eaba0599, 2020 | 75 | 2020 |
A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation J Rasouli, G Casella, S Yoshimura, W Zhang, D Xiao, J Garifallou, ... Science Immunology 5 (52), eaba9953, 2020 | 52 | 2020 |
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity W Zhang, D Xiao, X Li, Y Zhang, J Rasouli, G Casella, A Boehm, ... The Journal of Clinical Investigation 132 (22), 2022 | 29 | 2022 |
A fiber chimeric CRAd vector Ad5/11-D24 double-armed with TRAIL and arresten for enhanced glioblastoma therapy X Li, Q Mao, D Wang, W Zhang, H Xia Human gene therapy 23 (6), 589-596, 2012 | 29 | 2012 |
CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation D Hwang, MS Seyedsadr, LLW Ishikawa, A Boehm, Z Sahin, G Casella, ... Proceedings of the National Academy of Sciences 119 (14), e2111804119, 2022 | 25 | 2022 |
Generation of apoptosis‐resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production W Zhang, D Xiao, L Shan, J Zhao, Q Mao, H Xia Biotechnology and Bioengineering 114 (11), 2539-2549, 2017 | 19 | 2017 |
Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing W Zhang, D Wang, S Liu, X Zheng, H Ji, H Xia, Q Mao Gene therapy 21 (3), 282-288, 2014 | 18 | 2014 |
A novel luciferase knock-in reporter system for studying transcriptional regulation of the human Sox2 gene D Xiao, W Zhang, Y Li, K Liu, J Zhao, X Sun, L Shan, Q Mao, H Xia Journal of Biotechnology 219, 110-116, 2016 | 16 | 2016 |
Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells S Liu, Q Mao, W Zhang, X Zheng, Y Bian, D Wang, H Li, L Chai, J Zhao, ... Bioscience reports 29 (2), 103-109, 2009 | 16 | 2009 |
IFN-β acts on monocytes to ameliorate CNS autoimmunity by inhibiting proinflammatory cross-talk between monocytes and Th cells J Rasouli, G Casella, LLW Ishikawa, R Thome, A Boehm, A Ertel, ... Frontiers in immunology 12, 679498, 2021 | 15 | 2021 |
CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology D Xiao, W Zhang, Q Wang, X Li, Y Zhang, J Rasouli, G Casella, B Ciric, ... Molecular Therapy-Methods & Clinical Development 20, 755-764, 2021 | 11 | 2021 |
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis XY Ji, YX Guo, LB Wang, WC Wu, JQ Wang, J He, R Gao, J Rasouli, ... Journal of Neuroinflammation 21 (1), 29, 2024 | 9 | 2024 |
Interferon-γ/Interleukin-27 axis induces programmed death ligand 1 expression in monocyte-derived dendritic cells and restores immune tolerance in central nervous system … G Casella, J Rasouli, R Thome, HC Descamps, A Vattikonda, L Ishikawa, ... Frontiers in immunology 11, 576752, 2020 | 9 | 2020 |
Targeted genome correction by a single adenoviral vector simultaneously carrying an inducible zinc finger nuclease and a donor template W Zhang, H Chen, X Zheng, D Wang, H Ji, H Xia, Q Mao Journal of Biotechnology 188, 1-6, 2014 | 9 | 2014 |
Transcription factor RUNX3 mediates plasticity of ThGM cells toward Th1 phenotype J Rasouli, G Casella, W Zhang, D Xiao, G Kumar, P Fortina, GX Zhang, ... Frontiers in Immunology 13, 912583, 2022 | 7 | 2022 |
Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter system W Zhang, Y Guo, C Zhang, H Ji, W Meng, D Wang, X Li, Q Mao, H Xia Public Library of Science 7 (9), e45169, 2012 | 7 | 2012 |
P7C3 attenuates CNS autoimmunity by inhibiting Th17 cell differentiation X Li, Y Zhang, WF Zhang, D Xiao, B Ciric, A Rostami, GX Zhang Cellular & Molecular Immunology 18 (6), 1565-1567, 2021 | 5 | 2021 |
Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system Y Li, W Zhang, J Zhao, S Li, L Shan, J Zhu, Y Li, H Zhu, Q Mao, H Xia Cytotechnology 70, 1595-1605, 2018 | 5 | 2018 |
Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs W Zhang, X Zheng, Y Wang, Q Mao, H Xia Journal of biotechnology 162 (2-3), 191-196, 2012 | 2 | 2012 |