| Establishing a Role for Bacterial Cellulose in Environmental Interactions: Lessons Learned from Diverse Biofilm-Producing Proteobacteria RV Augimeri, AJ Varley, JL Strap Frontiers in microbiology 6, 1282, 2015 | 144 | 2015 |
| Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing B Li, RS Manan, SQ Liang, A Gordon, A Jiang, A Varley, G Gao, R Langer, ... Nature biotechnology 41 (10), 1410-1415, 2023 | 140 | 2023 |
| Clinical delivery of circular RNA: lessons learned from RNA drug development TL Young, KC Wang, AJ Varley, B Li Advanced Drug Delivery Reviews 197, 114826, 2023 | 65 | 2023 |
| Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry B Li, IO Raji, AGR Gordon, L Sun, TM Raimondo, FA Oladimeji, AY Jiang, ... Nature Materials 23 (7), 1002-1008, 2024 | 38 | 2024 |
| AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery Y Xu, S Ma, H Cui, J Chen, S Xu, F Gong, A Golubovic, M Zhou, KC Wang, ... Nature communications 15 (1), 6305, 2024 | 32 | 2024 |
| Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects J Chen, Y Xu, M Zhou, S Xu, AJ Varley, A Golubovic, RXZ Lu, KC Wang, ... Proceedings of the National Academy of Sciences 120 (50), e2309472120, 2023 | 32 | 2023 |
| Tumor‐tailored ionizable lipid nanoparticles facilitate IL‐12 circular RNA delivery for enhanced lung cancer immunotherapy S Xu, Y Xu, NC Solek, J Chen, F Gong, AJ Varley, A Golubovic, A Pan, ... Advanced Materials 36 (29), 2400307, 2024 | 25 | 2024 |
| Chemical strategies for strand selection in short-interfering RNAs AJ Varley, JP Desaulniers RSC advances 11 (4), 2415-2426, 2021 | 18 | 2021 |
| Effects of chemical modifications on siRNA strand selection in mammalian cells AJ Varley, ML Hammill, L Salim, JP Desaulniers nucleic acid therapeutics 30 (4), 229-236, 2020 | 12 | 2020 |
| Synthesis and evaluation of neutral phosphate triester backbone-modified siRNAs K Tsubaki, ML Hammill, AJ Varley, M Kitamura, T Okauchi, ... ACS Medicinal Chemistry Letters 11 (7), 1457-1462, 2020 | 12 | 2020 |
| SiRNAs with neutral phosphate triester hydrocarbon tails exhibit carrier-free gene-silencing activity ML Hammill, K Tsubaki, L Salim, AJ Varley, I Giorgees, M Kitamura, ... ACS Medicinal Chemistry Letters 13 (4), 695-700, 2022 | 9 | 2022 |
| Building siRNAs with cubes: synthesis and evaluation of cubane‐modified siRNAs ML Hammill, L Salim, K Tsubaki, AJ Varley, M Kitamura, T Okauchi, ... ChemBioChem 22 (20), 2981-2985, 2021 | 5 | 2021 |
| The transcription factor, FixK, plays a central role in carbon source metabolism and cellulose synthesis in Komagataeibacter species AJ Varley University of Ontario Institute of Technology (Canada), 2017 | 1 | 2017 |
| Utilizing the Ethylene-releasing Compound, 2-Chloroethylphosphonic Acid, as a Tool to Study Ethylene Response in Bacteria RV Augimeri, AJ Varley, JL Strap Journal of Visualized Experiments: JoVE, 54682, 2016 | 1 | 2016 |
| A Reverse Transcription Nucleic-Acid-Based Barcoding System for In Vivo Measurement of Lipid Nanoparticle mRNA Delivery KC Wang, TL Young, J Chen, SN Tsai, Y Xu, AJ Varley, NC Solek, F Gong, ... ACS Bio & Med Chem Au, 2025 | | 2025 |
| Zwitterionic Hydrogels: From Synthetic Design to Biomedical Applications L Gao, A Varley, H Gao, B Li, X Li Langmuir, 2025 | | 2025 |
| Suggested searches M Watson, D Sabirova, MC Hardy, Y Pan, DCJ Carpentier, H Yates, ... Perspective, 2024 | | 2024 |
| Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy (Adv. Mater. 29/2024) S Xu, Y Xu, NC Solek, J Chen, F Gong, AJ Varley, A Golubovic, A Pan, ... Advanced Materials 36 (29), 2470228, 2024 | | 2024 |
| Synthesis of 5’-fluorophosphate-modified short-interfering RNAs A Varley, JP Desaulniers Nucleosides, Nucleotides & Nucleic Acids 42 (5), 358-370, 2023 | | 2023 |
| Development and characterization of chemical modifications for siRNA strand selection AJ Varley | | 2021 |
Jean-Paul DesaulniersOntario Tech Universityبريد إلكتروني تم التحقق منه على ontariotechu.net