Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors C Granchi, G Bononi, R Ferrisi, E Gori, G Mantini, S Glasmacher, G Poli, ... European journal of medicinal chemistry 209, 112857, 2021 | 35 | 2021 |
Design, synthesis, and biological activity of new CB2 receptor ligands: From orthosteric and allosteric modulators to dualsteric/bitopic ligands F Gado, R Ferrisi, B Polini, KA Mohamed, C Ricardi, E Lucarini, S Carpi, ... Journal of Medicinal Chemistry 65 (14), 9918-9938, 2022 | 24 | 2022 |
Positive allosteric modulation of CB1 and CB2 cannabinoid receptors enhances the neuroprotective activity of a dual CB1R/CB2R orthosteric agonist B Polini, C Cervetto, S Carpi, S Pelassa, F Gado, R Ferrisi, S Bertini, ... Life 10 (12), 333, 2020 | 22 | 2020 |
Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB2R modulators in neurodegenerative diseases R Ferrisi, C Ceni, S Bertini, M Macchia, C Manera, F Gado Pharmacological Research 170, 105607, 2021 | 19 | 2021 |
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R) R Ferrisi, F Gado, B Polini, C Ricardi, KA Mohamed, LA Stevenson, ... Frontiers in Chemistry 10, 984069, 2022 | 13 | 2022 |
The role of cannabinoids in bone metabolism: a new perspective for bone disorders F Saponaro, R Ferrisi, F Gado, B Polini, A Saba, C Manera, G Chiellini International Journal of Molecular Sciences 22 (22), 12374, 2021 | 12 | 2021 |
Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor F Gado, KA Mohamed, S Meini, R Ferrisi, S Bertini, M Digiacomo, ... European Journal of Medicinal Chemistry 211, 113116, 2021 | 9 | 2021 |
Dual cannabinoid and orexin regulation of anhedonic behaviour caused by prolonged restraint stress HJJ Kim, A Zagzoog, C Ceni, R Ferrisi, N Janz, RB Laprairie Brain Sciences 13 (2), 314, 2023 | 8 | 2023 |
New insights into bitopic orthosteric/allosteric ligands of cannabinoid receptor type 2 R Ferrisi, B Polini, C Ricardi, F Gado, KA Mohamed, G Baron, S Faiella, ... International Journal of Molecular Sciences 24 (3), 2135, 2023 | 7 | 2023 |
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells F Gado, R Ferrisi, S Di Somma, F Napolitano, KA Mohamed, ... Molecules 27 (9), 3019, 2022 | 7 | 2022 |
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators F Gado, C Ceni, R Ferrisi, G Sbrana, LA Stevenson, M Macchia, ... European Journal of Pharmaceutical Sciences 169, 106088, 2022 | 6 | 2022 |
A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells B Polini, L Zallocco, F Gado, R Ferrisi, C Ricardi, M Zuccarini, V Carnicelli, ... Cells 13 (10), 875, 2024 | 4 | 2024 |
The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer’s Disease R Ferrisi, F Gado, C Ricardi, B Polini, C Manera, G Chiellini Journal of Clinical Medicine 12 (23), 7201, 2023 | 4 | 2023 |
Synthesis and optimization of benzoylpiperidine derivatives as Monoacylglycerol Lipase (MAGL) inhibitors. R FERRISI | 1 | 2019 |
Sulfonium Moieties as Ammonium Bioisosteres: Novel Ligands for the Alpha7 Nicotinic Acetylcholine Receptor C Papotto, C Stokes, C Matera, SM Herz, K Chiang, R Ferrisi, M De Amici, ... Journal of Medicinal Chemistry, 2025 | | 2025 |
Novel Orthosteric/Allosteric Ligands of Cannabinoid Receptors: An Unexpected Pharmacological Profile R Ferrisi, B Polini, AM Smolyakova, C Migone, G Giammattei, M Banti, ... Journal of Medicinal Chemistry, 2025 | | 2025 |
Design, synthesis, and biological evaluation of allosteric and bitopic ligands for novel strategies targeting G protein-coupled receptors: a special focus on cannabinoid receptors R FERRISI | | 2023 |