Decade-long leukaemia remissions with persistence of CD4+ CAR T cells JJ Melenhorst, GM Chen, M Wang, DL Porter, C Chen, MKA Collins, ... Nature 602 (7897), 503-509, 2022 | 683 | 2022 |
Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL Z Bai, S Woodhouse, Z Zhao, R Arya, K Govek, D Kim, S Lundh, A Baysoy, ... Science advances 8 (23), eabj2820, 2022 | 112 | 2022 |
PP2A holoenzymes, substrate specificity driving cellular functions and deregulation in cancer H Fowle, Z Zhao, X Graña Advances in Cancer Research 144, 55-93, 2019 | 78 | 2019 |
PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome … Z Zhao, A Kurimchak, AS Nikonova, F Feiser, JS Wasserman, H Fowle, ... Oncogenesis 8 (12), 72, 2019 | 29 | 2019 |
PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107 H Fowle, Z Zhao, Q Xu, JS Wasserman, X Wang, M Adeyemi, F Feiser, ... Elife 10, e63181, 2021 | 27 | 2021 |
Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase Z Zhao, H Fowle, H Valentine, Z Liu, Y Tan, J Pei, S Badal, JR Testa, ... Prostate cancer and prostatic diseases 24 (1), 233-243, 2021 | 20 | 2021 |
Single-cell CAR T atlas reveals type 2 function in 8-year leukaemia remission Z Bai, B Feng, SE McClory, BC de Oliveira, C Diorio, C Gregoire, B Tao, ... Nature 634 (8034), 702-711, 2024 | 10 | 2024 |
Enhanced costimulatory signaling improves CAR T-cell effector responses in CLL MKA Collins, IY Jung, Z Zhao, K Apodaca, W Kong, S Lundh, JA Fraietta, ... Cancer research communications 2 (9), 1089-1103, 2022 | 10 | 2022 |
Challenges and opportunities of CAR T-cell therapies for CLL Z Zhao, C Grégoire, B Oliveira, K Chung, JJ Melenhorst Seminars in Hematology 60 (1), 25-33, 2023 | 6 | 2023 |
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient H Valentine, W Aiken, B Morrison, Z Zhao, H Fowle, JS Wasserman, ... Cancer research communications 2 (11), 1355-1371, 2022 | 6 | 2022 |
Fam122a Ensures Cell Cycle Interphase Progression and Checkpoint Control as a SLiM-Dependent Substrate-Competitive Inhibitor to the B55α/PP2a Phosphatase J Wasserman Temple University, 2023 | 5 | 2023 |
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs JS Wasserman, B Faezov, KR Patel, AM Kurimchak, SM Palacio, ... Nature Communications 15 (1), 5776, 2024 | 1 | 2024 |
Adaptable leukemia cells resisting CAR T-cell attack via B-cell activation Z Zhao, JJ Melenhorst Cancer Immunology Research 10 (9), 1040-1040, 2022 | 1 | 2022 |
Analysis of the tumor suppressor function of B55alpha, the PP2A regulatory subunit encoded by PPP2R2A, in prostate cancer cells Z Zhao, A Kurimchak, M Adeyemi, P Woodruff, V Kolenko, X Graña Cancer Research 76 (14_Supplement), 3662-3662, 2016 | 1 | 2016 |
Single-Cell Multi-Omics Reveals Type-2 Functionality in Maintaining CAR T Cell Longevity Associated with 8-Year Leukemia Remission Z Bai, B Feng, SE Mcclory, C Diorio, Z Zhao, L Tang, JJ Melenhorst, ... Blood 142, 352, 2023 | | 2023 |
229 Large-scale omics profiling reveals type-2 functionality sustaining 8-year leukemia remission following CAR T cell therapy Z Bai, B Feng, S McClory, C Diorio, Z Zhao, L Tang, J Melenhorst, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Co-stimulatory signaling boosts CAR T cell efficacy against chronic lymphocytic leukemia Z Zhao, MK Collins, C Sun, A Wiestner, JJ Melenhorst Cancer Research 83 (7_Supplement), 4100-4100, 2023 | | 2023 |
Co-Stimulatory Signaling Boosts CAR T Cell Efficacy Against CLL Z Zhao, MK Collins, C Sun, A Wiestner, JJ Melenhorst Blood 140 (Supplement 1), 10255-10256, 2022 | | 2022 |
Abstract PO-138: The first Caribbean cell line, a prostate cancer cell line: ACRJ-PC28 H Valentine, W Aiken, B Morrison, Z Zhao, H Fowle, JS Wasserman, ... Cancer Epidemiology, Biomarkers & Prevention 31 (1_Supplement), PO-138-PO-138, 2022 | | 2022 |
Reconstituting B55/protein phosphatase 2A activity in B55/PP2A-defective prostate cancer cells suppresses proliferation and tumorigenicity through pleiotropic mechanisms Z Zhao, A Kurimchak, P Makhov, K Johnson, V Kolenko, J Duncan, ... CANCER RESEARCH 77, 2017 | | 2017 |