| Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: a review J Bicker, G Alves, A Fortuna, A Falcão European Journal of Pharmaceutics and Biopharmaceutics 87 (3), 409-432, 2014 | 324 | 2014 |
| Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples—A review J Bicker, A Fortuna, G Alves, A Falcao Analytica chimica acta 768, 12-34, 2013 | 216 | 2013 |
| ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches K Leandro, J Bicker, G Alves, A Falcão, A Fortuna Pharmacological research 144, 357-376, 2019 | 73 | 2019 |
| Development, validation and application of a new HPLC-DAD method for simultaneous quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma F Gouveia, J Bicker, J Santos, M Rocha, G Alves, A Falcão, A Fortuna Journal of Pharmaceutical and Biomedical Analysis 181, 113109, 2020 | 66 | 2020 |
| Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics J Bicker, G Alves, A Falcão, A Fortuna British Journal of Pharmacology 177 (10), 2215-2239, 2020 | 64 | 2020 |
| A new PAMPA model using an in-house brain lipid extract for screening the blood–brain barrier permeability of drug candidates J Bicker, G Alves, A Fortuna, P Soares-da-Silva, A Falcão International journal of pharmaceutics 501 (1-2), 102-111, 2016 | 61 | 2016 |
| Nose-to-brain delivery of levetiracetam after intranasal administration to mice J Gonçalves, J Bicker, F Gouveia, J Liberal, RC Oliveira, G Alves, ... International journal of pharmaceutics 564, 329-339, 2019 | 58 | 2019 |
| Antidepressants and nose-to-brain delivery: drivers, restraints, opportunities and challenges C Vitorino, S Silva, J Bicker, A Falcão, A Fortuna Drug Discovery Today 24 (9), 1911-1923, 2019 | 38 | 2019 |
| Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review F Gouveia, J Bicker, J Gonçalves, G Alves, A Falcão, A Fortuna Analytica chimica acta, 2019 | 37 | 2019 |
| Elucidation of the impact of p-glycoprotein and breast cancer resistance protein on the brain distribution of catechol-o-methyltransferase inhibitors J Bicker, A Fortuna, G Alves, P Soares-da-Silva, A Falcão Drug Metabolism and Disposition 45 (12), 1282-1291, 2017 | 29 | 2017 |
| Nose-to-brain delivery of natural compounds for the treatment of central nervous system disorders J Bicker, A Fortuna, G Alves, A Falcão Current Pharmaceutical Design 26 (5), 594-619, 2020 | 26 | 2020 |
| Anti-PD-1 immunotherapy in advanced metastatic melanoma: State of the art and future challenges RS Moreira, J Bicker, F Musicco, A Persichetti, AMPT Pereira Life sciences 240, 117093, 2020 | 26 | 2020 |
| A chiral HPLC‐UV method for the quantification of dibenz [b, f] azepine‐5‐carboxamide derivatives in mouse plasma and brain tissue: Eslicarbazepine acetate, carbamazepine and … A Fortuna, J Bicker, G Alves, A Falcão, P Soares‐da‐Silva Journal of separation science 34 (12), 1391-1401, 2011 | 25 | 2011 |
| Development and full validation of an innovative HPLC-diode array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma J Gonçalves, G Alves, J Bicker, A Falcão, A Fortuna Bioanalysis 10 (8), 541-557, 2018 | 23 | 2018 |
| Relevance of breast cancer resistance protein to brain distribution and central acting drugs: a pharmacokinetic perspective J Goncalves, J Bicker, G Alves, A Fortuna, A Falcao Current drug metabolism 19 (12), 1021-1041, 2018 | 14 | 2018 |
| In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein J Bicker, G Alves, A Fortuna, P Soares-da-Silva, A Falcão European Journal of Pharmaceutical Sciences 117, 35-40, 2018 | 11 | 2018 |
| Screening of pharmacokinetic properties of fifty dihydropyrimidin (thi) one derivatives using a combo of in vitro and in silico assays M Matias, A Fortuna, J Bicker, S Silvestre, A Falcão, G Alves European Journal of Pharmaceutical Sciences 109, 334-346, 2017 | 10 | 2017 |
| Therapeutic drug monitoring of levetiracetam: pharmacokinetic characterization and compliance assessment of epileptic patients J Goncalves, R Silva, A Almeida, J Bicker, A Silva, F Sales, A Falcao, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 220-220, 2019 | | 2019 |
