Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain A Chakraborty, MA Koldobskiy, NT Bello, M Maxwell, JJ Potter, KR Juluri, ... Cell 143 (6), 897-910, 2010 | 406 | 2010 |
Inositol pyrophosphates as mammalian cell signals A Chakraborty, S Kim, SH Snyder Science signaling 4 (188), re1-re1, 2011 | 179 | 2011 |
Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase S Kim, SF Kim, D Maag, MJ Maxwell, AC Resnick, KR Juluri, ... Cell metabolism 13 (2), 215-221, 2011 | 166 | 2011 |
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2 A Chakraborty, MA Koldobskiy, KM Sixt, KR Juluri, AK Mustafa, ... Proceedings of the National Academy of Sciences 105 (4), 1134-1139, 2008 | 130 | 2008 |
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2 MA Koldobskiy, A Chakraborty, JK Werner Jr, AM Snowman, KR Juluri, ... Proceedings of the National Academy of Sciences 107 (49), 20947-20951, 2010 | 119 | 2010 |
The inositol pyrophosphate pathway in health and diseases A Chakraborty Biological Reviews 93 (2), 1203-1227, 2018 | 104 | 2018 |
Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3, 4, 5)-trisphosphate signaling A Prasad, Y Jia, A Chakraborty, Y Li, SK Jain, J Zhong, SG Roy, F Loison, ... Nature immunology 12 (8), 752-760, 2011 | 88 | 2011 |
Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis Q Zhu, S Ghoshal, A Rodrigues, S Gao, A Asterian, TM Kamenecka, ... The Journal of clinical investigation 126 (11), 4273-4288, 2016 | 86 | 2016 |
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition AK Mustafa, DB Rossum, RL Patterson, D Maag, JT Ehmsen, SK Gazi, ... Proceedings of the National Academy of Sciences 106 (8), 2921-2926, 2009 | 80 | 2009 |
Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2 A Chakraborty, JK Werner Jr, MA Koldobskiy, AK Mustafa, KR Juluri, ... Proceedings of the National Academy of Sciences 108 (6), 2205-2209, 2011 | 61 | 2011 |
TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl) purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway S Ghoshal, Q Zhu, A Asteian, H Lin, H Xu, G Ernst, JC Barrow, B Xu, ... Molecular metabolism 5 (10), 903-917, 2016 | 59 | 2016 |
Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4–signalosome complex to regulate DNA repair and cell death F Rao, J Xu, AB Khan, MM Gadalla, JY Cha, R Xu, R Tyagi, Y Dang, ... Proceedings of the National Academy of Sciences 111 (45), 16005-16010, 2014 | 59 | 2014 |
Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways A Chakraborty, C Latapy, J Xu, SH Snyder, JM Beaulieu Molecular psychiatry 19 (3), 284-293, 2014 | 56 | 2014 |
Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia Q Hou, F Liu, A Chakraborty, Y Jia, A Prasad, H Yu, L Zhao, K Ye, ... Science translational medicine 10 (435), eaal4045, 2018 | 49 | 2018 |
A Single-domain Cyclophilin from Leishmania donovaniReactivates Soluble Aggregates of Adenosine Kinase by Isomerase-independent Chaperone Function A Chakraborty, I Das, R Datta, B Sen, D Bhattacharyya, C Mandal, ... Journal of Biological Chemistry 277 (49), 47451-47460, 2002 | 47 | 2002 |
Inhibition of inositol polyphosphate kinases by quercetin and related flavonoids: a structure–activity analysis C Gu, MA Stashko, AC Puhl-Rubio, M Chakraborty, A Chakraborty, ... Journal of medicinal chemistry 62 (3), 1443-1454, 2019 | 46 | 2019 |
Targeting the inositol pyrophosphate biosynthetic enzymes in metabolic diseases S Mukherjee, J Haubner, A Chakraborty Molecules 25 (6), 1403, 2020 | 42 | 2020 |
Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain Q Zhu, S Ghoshal, R Tyagi, A Chakraborty Molecular metabolism 6 (1), 73-85, 2017 | 42 | 2017 |
Inositol hexakisphosphate kinase-1 interacts with perilipin1 to modulate lipolysis S Ghoshal, R Tyagi, Q Zhu, A Chakraborty The international journal of biochemistry & cell biology 78, 149-155, 2016 | 32 | 2016 |
Isomerase-independent chaperone function of cyclophilin ensures aggregation prevention of adenosine kinase both in vitro and under in vivo conditions A Chakraborty, B Sen, R Datta, AK Datta Biochemistry 43 (37), 11862-11872, 2004 | 29 | 2004 |