Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner VK Gupta, L Scheunemann, T Eisenberg, S Mertel, A Bhukel, ... Nature neuroscience 16 (10), 1453-1460, 2013 | 377 | 2013 |
Systematic phenomics analysis deconvolutes genes mutated in intellectual disability into biologically coherent modules K Kochinke, C Zweier, B Nijhof, M Fenckova, P Cizek, F Honti, ... The American Journal of Human Genetics 98 (1), 149-164, 2016 | 351 | 2016 |
Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability T Kleefstra, JM Kramer, K Neveling, MH Willemsen, TS Koemans, ... The American Journal of Human Genetics 91 (1), 73-82, 2012 | 306 | 2012 |
Expressionof Drosophila FOXO regulates growth and can phenocopy starvation JM Kramer, JT Davidge, JM Lockyer, BE Staveley BMC developmental biology 3, 1-14, 2003 | 270 | 2003 |
Mutations in the chromatin modifier gene KANSL1 cause the 17q21.31 microdeletion syndrome DA Koolen, JM Kramer, K Neveling, WM Nillesen, HL Moore-Barton, ... Nature genetics 44 (6), 639-641, 2012 | 257 | 2012 |
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a JM Kramer, K Kochinke, MAW Oortveld, H Marks, D Kramer, EK de Jong, ... PLoS biology 9 (1), e1000569, 2011 | 243 | 2011 |
Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders Z Iqbal, G Vandeweyer, M van der Voet, AM Waryah, MY Zahoor, ... Human molecular genetics 22 (10), 1960-1970, 2013 | 184 | 2013 |
Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder TS Koemans, T Kleefstra, MC Chubak, MH Stone, MRF Reijnders, ... PLoS genetics 13 (10), e1006864, 2017 | 162 | 2017 |
GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster JM Kramer, BE Staveley Genet Mol Res 2 (1), 43-47, 2003 | 162 | 2003 |
The genetics of cognitive epigenetics T Kleefstra, A Schenck, JM Kramer, H Van Bokhoven Neuropharmacology 80, 83-94, 2014 | 125 | 2014 |
SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway ST Cliffe, JM Kramer, K Hussain, JH Robben, EK de Jong, AP de Brouwer, ... Human molecular genetics 18 (12), 2257-2265, 2009 | 125 | 2009 |
The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila SH Merkling, AW Bronkhorst, JM Kramer, GJ Overheul, A Schenck, ... PLoS pathogens 11 (4), e1004692, 2015 | 106 | 2015 |
Genetic and epigenetic defects in mental retardation JM Kramer, H van Bokhoven The international journal of biochemistry & cell biology 41 (1), 96-107, 2009 | 105 | 2009 |
Epigenetic mechanisms modulate differences in Drosophila foraging behavior I Anreiter, JM Kramer, MB Sokolowski Proceedings of the National Academy of Sciences 114 (47), 12518-12523, 2017 | 87 | 2017 |
CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation A Mukhopadhyay, JM Kramer, G Merkx, D Lugtenberg, DF Smeets, ... Human genetics 128, 281-291, 2010 | 81 | 2010 |
Drosophila courtship conditioning as a measure of learning and memory TS Koemans, C Oppitz, RAT Donders, H van Bokhoven, A Schenck, ... Journal of visualized experiments: JoVE, 55808, 2017 | 71 | 2017 |
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration A Dubos, A Castells-Nobau, H Meziane, MAW Oortveld, X Houbaert, ... Human molecular genetics 24 (23), 6736-6755, 2015 | 70 | 2015 |
Disruption of the epigenetic code: an emerging mechanism in mental retardation H van Bokhoven, JM Kramer Neurobiology of disease 39 (1), 3-12, 2010 | 68 | 2010 |
foxo is required for resistance to amino acid starvation in Drosophila JM Kramer, JD Slade, BE Staveley Genome 51 (8), 668-672, 2008 | 62 | 2008 |
Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome J Kummeling, DE Stremmelaar, N Raun, MRF Reijnders, MH Willemsen, ... Molecular psychiatry 26 (6), 2013-2024, 2021 | 61 | 2021 |