Pathways of chaperone-mediated protein folding in the cytosol JC Young, VR Agashe, K Siegers, FU Hartl Nature reviews Molecular cell biology 5 (10), 781-791, 2004 | 1458 | 2004 |
Hsp90: a specialized but essential protein-folding tool JC Young, I Moarefi, FU Hartl The Journal of cell biology 154 (2), 267, 2001 | 1135 | 2001 |
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70 JC Young, NJ Hoogenraad, FU Hartl Cell 112 (1), 41-50, 2003 | 1057 | 2003 |
More than folding: localized functions of cytosolic chaperones JC Young, JM Barral, FU Hartl Trends in biochemical sciences 28 (10), 541-547, 2003 | 509 | 2003 |
Peripheral protein quality control removes unfolded CFTR from the plasma membrane T Okiyoneda, H Barrière, M Bagdány, WM Rabeh, K Du, J Höhfeld, ... Science 329 (5993), 805-810, 2010 | 486 | 2010 |
Deoxynivalenol and Fusarium head blight resistance in spring cereals JD Miller, JC Young, DR Sampson Journal of Phytopathology 113 (4), 359-367, 1985 | 415 | 1985 |
Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90 JC Young, WMJ Obermann, FU Hartl Journal of Biological Chemistry 273 (29), 18007-18010, 1998 | 345 | 1998 |
Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co‐chaperone p23 JC Young, FU Hartl The EMBO journal, 2000 | 317 | 2000 |
Mechanisms of the Hsp70 chaperone system JC Young Biochemistry and Cell Biology 88 (2), 291-300, 2010 | 290 | 2010 |
Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange Y Shomura, Z Dragovic, HC Chang, N Tzvetkov, JC Young, JL Brodsky, ... Molecular cell 17 (3), 367-379, 2005 | 273 | 2005 |
In vitro evidence that hsp90 contains two independent chaperone sites JC Young, C Schneider, FU Hartl FEBS letters 418 (1-2), 139-143, 1997 | 194 | 1997 |
Function, evolution, and structure of J-domain proteins HH Kampinga, C Andreasson, A Barducci, ME Cheetham, D Cyr, ... Cell Stress and Chaperones 24, 7-15, 2019 | 166 | 2019 |
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system A Brychzy, T Rein, KF Winklhofer, FU Hartl, JC Young, WMJ Obermann The EMBO journal, 2003 | 153 | 2003 |
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones BM Abell, C Rabu, P Leznicki, JC Young, S High Journal of cell science 120 (10), 1743-1751, 2007 | 132 | 2007 |
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90 A Orthwein, AM Patenaude, EB Affar, A Lamarre, JC Young, JM Di Noia Journal of Experimental Medicine 207 (12), 2751-2765, 2010 | 130 | 2010 |
Hsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import ACY Fan, MK Bhangoo, JC Young Journal of biological chemistry 281 (44), 33313-33324, 2006 | 123 | 2006 |
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import MK Bhangoo, S Tzankov, ACY Fan, K Dejgaard, DY Thomas, JC Young Molecular biology of the cell 18 (9), 3414-3428, 2007 | 116 | 2007 |
Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein A Rodina, PD Patel, Y Kang, Y Patel, I Baaklini, MJH Wong, T Taldone, ... Chemistry & biology 20 (12), 1469-1480, 2013 | 114 | 2013 |
Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae H Sondermann, AK Ho, LL Listenberger, K Siegers, I Moarefi, SR Wente, ... Journal of biological chemistry 277 (36), 33220-33227, 2002 | 113 | 2002 |
Dynamic comparisons of piezoelectric ejecta diagnostics WT Buttler, MB Zellner, RT Olson, PA Rigg, RS Hixson, JE Hammerberg, ... Journal of applied physics 101 (6), 2007 | 100 | 2007 |