مقالات بحثية تمّ التفويض بإتاحتها للجميع - Jonathan M. Ghergurovich, MD, PhDمزيد من المعلومات
عدد المقالات البحثية المتاحة للجميع في موقع ما: 15
مراجعة
Glucose feeds the TCA cycle via circulating lactate‏
S Hui, JM Ghergurovich, RJ Morscher, C Jang, X Teng, W Lu, LA Esparza, ...‏
Nature 551 (7678), 115-118, 2017‏
التفويضات: US National Institutes of Health, Cancer Research UK‏
مراجعة
Reversal of cytosolic one-carbon flux compensates for loss of the mitochondrial folate pathway‏
GS Ducker, L Chen, RJ Morscher, JM Ghergurovich, M Esposito, X Teng, ...‏
Cell metabolism 23 (6), 1140-1153, 2016‏
التفويضات: US National Institutes of Health‏
مراجعة
Mitochondrial biogenesis and proteome remodeling promote one-carbon metabolism for T cell activation‏
N Ron-Harel, D Santos, JM Ghergurovich, PT Sage, A Reddy, SB Lovitch, ...‏
Cell metabolism 24 (1), 104-117, 2016‏
التفويضات: US National Institutes of Health, European Molecular Biology Laboratory …‏
مراجعة
As extracellular glutamine levels decline, asparagine becomes an essential amino acid‏
NN Pavlova, S Hui, JM Ghergurovich, J Fan, AM Intlekofer, RM White, ...‏
Cell metabolism 27 (2), 428-438. e5, 2018‏
التفويضات: US National Institutes of Health‏
مراجعة
Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma‏
GS Ducker, JM Ghergurovich, N Mainolfi, V Suri, SK Jeong, ...‏
Proceedings of the National Academy of Sciences 114 (43), 11404-11409, 2017‏
التفويضات: US Department of Energy, US National Institutes of Health‏
مراجعة
Serine catabolism feeds NADH when respiration is impaired‏
L Yang, JCG Canaveras, Z Chen, L Wang, L Liang, C Jang, JA Mayr, ...‏
Cell metabolism 31 (4), 809-821. e6, 2020‏
التفويضات: US National Institutes of Health, Howard Hughes Medical Institute, European …‏
مراجعة
T cell activation depends on extracellular alanine‏
N Ron-Harel, JM Ghergurovich, G Notarangelo, MW LaFleur, ...‏
Cell reports 28 (12), 3011-3021. e4, 2019‏
التفويضات: US National Science Foundation, US National Institutes of Health, European …‏
مراجعة
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway‏
JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ...‏
Nature chemical biology 16 (7), 731-739, 2020‏
التفويضات: US National Institutes of Health, European Commission‏
مراجعة
Defective respiration and one-carbon metabolism contribute to impaired naive T cell activation in aged mice‏
N Ron-Harel, G Notarangelo, JM Ghergurovich, JA Paulo, PT Sage, ...‏
Proceedings of the National Academy of Sciences 115 (52), 13347-13352, 2018‏
التفويضات: US National Institutes of Health, European Molecular Biology Laboratory‏
مراجعة
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia‏
JC García-Cañaveras, O Lancho, GS Ducker, JM Ghergurovich, X Xu, ...‏
Leukemia 35 (2), 377-388, 2021‏
التفويضات: US National Institutes of Health, European Commission, Alex's Lemonade Stand‏
مراجعة
Upregulation of antioxidant capacity and nucleotide precursor availability suffices for oncogenic transformation‏
Y Zhang, Y Xu, W Lu, JM Ghergurovich, L Guo, IA Blair, JD Rabinowitz, ...‏
Cell metabolism 33 (1), 94-109. e8, 2021‏
التفويضات: US Department of Defense, US National Institutes of Health‏
مراجعة
Methionine synthase supports tumour tetrahydrofolate pools‏
JM Ghergurovich, X Xu, JZ Wang, L Yang, RP Ryseck, L Wang, ...‏
Nature metabolism 3 (11), 1512-1520, 2021‏
التفويضات: US National Institutes of Health‏
مراجعة
Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer‏
JM Ghergurovich, JD Lang, MK Levin, N Briones, SJ Facista, C Mueller, ...‏
Med 2 (6), 736-754. e6, 2021‏
التفويضات: US National Institutes of Health‏
مراجعة
Glucose-6-phosphate dehydrogenase is not essential for K-ras–driven tumor growth or metastasis‏
JM Ghergurovich, M Esposito, Z Chen, JZ Wang, V Bhatt, T Lan, E White, ...‏
Cancer research 80 (18), 3820-3829, 2020‏
التفويضات: US National Institutes of Health, Lung Cancer Research Foundation, USA …‏
مراجعة
G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer‏
T Lan, S Arastu, S Wang, J Lam, W Wang, V Bhatt, EC Lopes, Z Hu, ...‏
bioRxiv, 2023‏
التفويضات: US National Institutes of Health‏
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