| Deficiency of terminal ADP‐ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease R Sharifi, R Morra, C Denise Appel, M Tallis, B Chioza, G Jankevicius, ... The EMBO journal 32 (9), 1225-1237, 2013 | 339 | 2013 |
| DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1 X Guo, JG Williams, TT Schug, X Li Journal of Biological Chemistry 285 (17), 13223-13232, 2010 | 281 | 2010 |
| Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2 J Pi, Y Bai, JM Reece, J Williams, D Liu, ML Freeman, WE Fahl, D Shugar, ... Free Radical Biology and Medicine 42 (12), 1797-1806, 2007 | 253 | 2007 |
| Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis JT Smyth, JG Petranka, RR Boyles, WI DeHaven, M Fukushima, ... Nature cell biology 11 (12), 1465-1472, 2009 | 199 | 2009 |
| Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway I Shats, JG Williams, J Liu, MV Makarov, X Wu, FB Lih, LJ Deterding, ... Cell metabolism 31 (3), 564-579. e7, 2020 | 185 | 2020 |
| Ligand-independent phosphorylation of the glucocorticoid receptor integrates cellular stress pathways with nuclear receptor signaling AJ Galliher-Beckley, JG Williams, JA Cidlowski Molecular and cellular biology, 2011 | 177 | 2011 |
| ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links MJ Schellenberg, JA Lieberman, A Herrero-Ruiz, LR Butler, JG Williams, ... Science 357 (6358), 1412-1416, 2017 | 173 | 2017 |
| Glycogen synthase kinase 3β-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles AJ Galliher-Beckley, JG Williams, JB Collins, JA Cidlowski Molecular and cellular biology, 2008 | 157 | 2008 |
| Lactate dehydrogenase C and energy metabolism in mouse sperm F Odet, SA Gabel, J Williams, RE London, E Goldberg, EM Eddy Biology of reproduction 85 (3), 556-564, 2011 | 140 | 2011 |
| The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10 GA Lemieux, F Blumenkron, N Yeung, P Zhou, J Williams, AC Grammer, ... Journal of Biological Chemistry 282 (20), 14836-14844, 2007 | 139 | 2007 |
| NMR characterization of full-length farnesylated and non-farnesylated H-Ras and its implications for Raf activation R Thapar, JG Williams, SL Campbell Journal of molecular biology 343 (5), 1391-1408, 2004 | 139 | 2004 |
| Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress JH Choi, J Williams, J Cho, JR Falck, SB Shears Journal of Biological Chemistry 282 (42), 30763-30775, 2007 | 131 | 2007 |
| Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange JG Williams, K Pappu, SL Campbell Proceedings of the National Academy of Sciences 100 (11), 6376-6381, 2003 | 126 | 2003 |
| Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics MC Pillon, MN Frazier, LB Dillard, JG Williams, S Kocaman, JM Krahn, ... Nature communications 12 (1), 636, 2021 | 125 | 2021 |
| Elucidation of binding determinants and functional consequences of Ras/Raf-cysteine-rich domain interactions JG Williams, JK Drugan, GS Yi, GJ Clark, CJ Der, SL Campbell Journal of Biological Chemistry 275 (29), 22172-22179, 2000 | 125 | 2000 |
| Diversity in penaeidin antimicrobial peptide form and function BJ Cuthbertson, LJ Deterding, JG Williams, KB Tomer, K Etienne, ... Developmental & Comparative Immunology 32 (3), 167-181, 2008 | 109 | 2008 |
| Disruption of a Spermatogenic Cell-Specific Mouse Enolase 4 (Eno4) Gene Causes Sperm Structural Defects and Male Infertility N Nakamura, Q Dai, J Williams, EH Goulding, WD Willis, PR Brown, ... Biology of reproduction 88 (4), 90, 1-12, 2013 | 107 | 2013 |
| A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal … NP Martin, E Marron Fernandez de Velasco, F Mizuno, EL Scappini, ... Endocrinology 155 (9), 3713-3724, 2014 | 90 | 2014 |
| HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer Q Xu, Y Li, X Gao, K Kang, JG Williams, L Tong, J Liu, M Ji, LJ Deterding, ... Nature communications 11 (1), 3978, 2020 | 84 | 2020 |
| Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3 BA Merrick, S Dhungana, JG Williams, JJ Aloor, S Peddada, KB Tomer, ... Molecular & Cellular Proteomics 10 (10), 2011 | 84 | 2011 |
