Grayanotoxin poisoning:‘mad honey disease’and beyond SA Jansen, I Kleerekooper, ZLM Hofman, IFPM Kappen, ... Cardiovascular toxicology 12, 208-215, 2012 | 222 | 2012 |
New potential binding determinant for hERG channel inhibitors P Saxena, EM Zangerl-Plessl, T Linder, A Windisch, A Hohaus, E Timin, ... Scientific Reports 6 (1), 24182, 2016 | 99 | 2016 |
Toward a consensus model of the HERG potassium channel A Stary, SJ Wacker, L Boukharta, U Zachariae, Y Karimi‐Nejad, J Åqvist, ... ChemMedChem 5 (3), 455-467, 2010 | 74 | 2010 |
Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids SJ Lee, F Ren, EM Zangerl-Plessl, S Heyman, A Stary-Weinzinger, ... Journal of General Physiology 148 (3), 227-237, 2016 | 69 | 2016 |
Computer simulations of structure–activity relationships for hERG channel blockers L Boukharta, H Keränen, A Stary-Weinzinger, G Wallin, BL de Groot, ... Biochemistry 50 (27), 6146-6156, 2011 | 51 | 2011 |
The anti‐protozoal drug pentamidine blocks KIR2.x‐mediated inward rectifier current by entering the cytoplasmic pore region of the channel TP De Boer, L Nalos, A Stary, B Kok, MJC Houtman, G Antoons, ... British journal of pharmacology 159 (7), 1532-1541, 2010 | 51 | 2010 |
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo I Baburin, R Varkevisser, A Schramm, P Saxena, S Beyl, P Szkokan, ... Pharmacological Research 131, 150-163, 2018 | 45 | 2018 |
Efficient and specific cardiac IK1 inhibition by a new pentamidine analogue H Takanari, L Nalos, A Stary-Weinzinger, KCG de Git, R Varkevisser, ... Cardiovascular research 99 (1), 203-214, 2013 | 43 | 2013 |
Probing the energy landscape of activation gating of the bacterial potassium channel KcsA T Linder, BL de Groot, A Stary-Weinzinger PLOS Computational Biology 9 (5), e1003058, 2013 | 43 | 2013 |
Timothy mutation disrupts the link between activation and inactivation in Cav1. 2 protein K Depil, S Beyl, A Stary-Weinzinger, A Hohaus, E Timin, S Hering Journal of Biological Chemistry 286 (36), 31557-31564, 2011 | 43 | 2011 |
Conduction through a narrow inward-rectifier K+ channel pore H Bernsteiner, EM Zangerl-Plessl, X Chen, A Stary-Weinzinger Journal of General Physiology 151 (10), 1231-1246, 2019 | 42 | 2019 |
Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide V Garg, A Stary-Weinzinger, F Sachse, MC Sanguinetti Molecular Pharmacology 80 (4), 630-637, 2011 | 42 | 2011 |
Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2. 2) channels EM Zangerl-Plessl, SJ Lee, G Maksaev, H Bernsteiner, F Ren, P Yuan, ... Journal of General Physiology 152 (1), e201912422, 2019 | 38 | 2019 |
Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine P Thurner, A Stary-Weinzinger, H Gafar, VS Gawali, O Kudlacek, J Zezula, ... The Journal of pharmacology and experimental therapeutics 348 (2), 346-358, 2014 | 38 | 2014 |
Distinct interactions of Na+ and Ca2+ ions with the selectivity filter of the bacterial sodium channel NaVAb S Ke, EM Zangerl, A Stary-Weinzinger Biochemical and Biophysical Research Communications 430 (4), 1272-1276, 2013 | 38 | 2013 |
Conserved functional consequences of disease-associated mutations in the slide helix of Kir6. 1 and Kir6. 2 subunits of the ATP-sensitive potassium channel PE Cooper, C McClenaghan, X Chen, A Stary-Weinzinger, CG Nichols Journal of Biological Chemistry 292 (42), 17387-17398, 2017 | 37 | 2017 |
Different Inward and Outward Conduction Mechanisms in NaVMs Suggested by Molecular Dynamics Simulations S Ke, EN Timin, A Stary-Weinzinger PLoS computational biology 10 (7), e1003746, 2014 | 34 | 2014 |
Disease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking EM Zangerl-Plessl, M Qile, M Bloothooft, A Stary-Weinzinger, ... Biomolecules 9 (11), 650, 2019 | 31 | 2019 |
ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels V Garg, A Stary-Weinzinger, MC Sanguinetti Molecular Pharmacology 83 (4), 805-813, 2013 | 29 | 2013 |
In silico analysis of conformational changes induced by mutation of aromatic binding residues: consequences for drug binding in the hERG K+ channel K Knape, T Linder, P Wolschann, A Beyer, A Stary-Weinzinger PloS one 6 (12), e28778, 2011 | 29 | 2011 |