Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport—an update Q Mao, JD Unadkat The AAPS journal 17, 65-82, 2015 | 721 | 2015 |
Imaging P‐glycoprotein transport activity at the human blood‐brain barrier with positron emission tomography L Sasongko, JM Link, M Muzi, DA Mankoff, X Yang, AC Collier, ... Clinical Pharmacology & Therapeutics 77 (6), 503-514, 2005 | 354 | 2005 |
Evaluation of the selectivity of in vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities D Hickman, JP Wang, YI Wang, JD Unadkat Drug Metabolism and Disposition 26 (3), 207-215, 1998 | 294 | 1998 |
HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2) A Gupta, YI Zhang, JD Unadkat, Q Mao The Journal of pharmacology and experimental therapeutics 310 (1), 334-341, 2004 | 292 | 2004 |
Protein abundance of clinically relevant multidrug transporters along the entire length of the human intestine M Drozdzik, C Gröer, J Penski, J Lapczuk, M Ostrowski, Y Lai, B Prasad, ... Molecular pharmaceutics 11 (10), 3547-3555, 2014 | 291 | 2014 |
Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice MF Hebert, X Ma, SB Naraharisetti, KM Krudys, JG Umans, GDV Hankins, ... Clinical Pharmacology & Therapeutics 85 (6), 607-614, 2009 | 276 | 2009 |
Effects of pregnancy on CYP3A and P‐glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study MF Hebert, TR Easterling, B Kirby, DB Carr, ML Buchanan, T Rutherford, ... Clinical Pharmacology & Therapeutics 84 (2), 248-253, 2008 | 274 | 2008 |
The role of transporters in drug interactions CJ Endres, P Hsiao, FS Chung, JD Unadkat european journal of pharmaceutical sciences 27 (5), 501-517, 2006 | 248 | 2006 |
Drug interactions at the blood-brain barrier: fact or fantasy? S Eyal, P Hsiao, JD Unadkat Pharmacology & therapeutics 123 (1), 80-104, 2009 | 234 | 2009 |
Transporters in drug development: 2018 ITC recommendations for transporters of emerging clinical importance MJ Zamek‐Gliszczynski, ME Taub, PP Chothe, X Chu, KM Giacomini, ... Clinical Pharmacology & Therapeutics 104 (5), 890-899, 2018 | 230 | 2018 |
P-glycoprotein and breast cancer resistance protein expression in human placentae of various gestational ages AA Mathias, J Hitti, JD Unadkat American Journal of Physiology-Regulatory, Integrative and Comparative …, 2005 | 222 | 2005 |
Activity of P-glycoprotein, a β-amyloid transporter at the blood–brain barrier, is compromised in patients with mild Alzheimer disease AK Deo, S Borson, JM Link, K Domino, JF Eary, B Ke, TL Richards, ... Journal of Nuclear Medicine 55 (7), 1106-1111, 2014 | 215 | 2014 |
Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem … B Prasad, R Evers, A Gupta, EC Cornelis, L Salphati, S Shukla, ... Drug Metabolism and Disposition 42 (1), 78-88, 2014 | 211 | 2014 |
Regulation of BCRP/ABCG2 expression by progesterone and 17β-estradiol in human placental BeWo cells H Wang, L Zhou, A Gupta, RR Vethanayagam, Y Zhang, JD Unadkat, ... American Journal of Physiology-Endocrinology and Metabolism 290 (5), E798-E807, 2006 | 205 | 2006 |
Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics L Wang, B Prasad, L Salphati, X Chu, A Gupta, CECA Hop, R Evers, ... Drug Metabolism and Disposition 43 (3), 367-374, 2015 | 203 | 2015 |
Expression of arylamine N-acetyltransferase in human intestine D Hickman, J Pope, SD Patil, G Fakis, V Smelt, LA Stanley, M Payton, ... Gut 42 (3), 402-409, 1998 | 188 | 1998 |
Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs Y Lai, CM Tse, JD Unadkat Journal of Biological Chemistry 279 (6), 4490-4497, 2004 | 176 | 2004 |
In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta R Govindarajan, AH Bakken, KL Hudkins, Y Lai, FJ Casado, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 169 | 2007 |
Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug … V Dixit, N Hariparsad, F Li, P Desai, KE Thummel, JD Unadkat Drug metabolism and disposition 35 (10), 1853-1859, 2007 | 166 | 2007 |
Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3 R Govindarajan, GPH Leung, M Zhou, CM Tse, J Wang, JD Unadkat American Journal of Physiology-Gastrointestinal and Liver Physiology 296 (4 …, 2009 | 163 | 2009 |