| The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice OF Bueno, LJ De Windt, KM Tymitz, SA Witt, TR Kimball, R Klevitsky, ... The EMBO journal, 2000 | 1011 | 2000 |
| MiR423-5p as a circulating biomarker for heart failure AJ Tijsen, EE Creemers, PD Moerland, LJ de Windt, AC van der Wal, ... Circulation research 106 (6), 1035-1039, 2010 | 877 | 2010 |
| The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo Q Liang, LJ De Windt, SA Witt, TR Kimball, BE Markham, JD Molkentin Journal of Biological Chemistry 276 (32), 30245-30253, 2001 | 470 | 2001 |
| Myocyte apoptosis in heart failure VPM van Empel, ATA Bertrand, L Hofstra, HJ Crijns, PA Doevendans, ... Cardiovascular research 67 (1), 21-29, 2005 | 451 | 2005 |
| Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy T Taigen, LJ De Windt, HW Lim, JD Molkentin Proceedings of the National Academy of Sciences 97 (3), 1196-1201, 2000 | 450 | 2000 |
| Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process WA Den Hengst, JF Gielis, JY Lin, PE Van Schil, LJ De Windt, AL Moens American Journal of Physiology-Heart and Circulatory Physiology 299 (5 …, 2010 | 447 | 2010 |
| MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling PA da Costa Martins, K Salic, MM Gladka, AS Armand, S Leptidis, ... Nature cell biology 12 (12), 1220-1227, 2010 | 410 | 2010 |
| Long noncoding RNA Chast promotes cardiac remodeling J Viereck, R Kumarswamy, A Foinquinos, K Xiao, P Avramopoulos, ... Science translational medicine 8 (326), 326ra22-326ra22, 2016 | 400 | 2016 |
| Conditional Dicer Gene Deletion in the Postnatal Myocardium Provokes Spontaneous Cardiac Remodeling PA da Costa Martins, M Bourajjaj, M Gladka, M Kortland, RJ van Oort, ... Circulation 118 (15), 1567-1576, 2008 | 385 | 2008 |
| A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression U Delling, J Tureckova, HW Lim, LJ De Windt, P Rotwein, JD Molkentin Molecular and cellular biology, 2000 | 380 | 2000 |
| Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy R Roncarati, C Viviani Anselmi, MA Losi, L Papa, E Cavarretta, ... Journal of the American College of Cardiology 63 (9), 920-927, 2014 | 373 | 2014 |
| MicroRNAs in heart failure: from biomarker to target for therapy EL Vegter, P van der Meer, LJ de Windt, YM Pinto, AA Voors European journal of heart failure 18 (5), 457-468, 2016 | 344 | 2016 |
| Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth BJ Wilkins, LJ De Windt, OF Bueno, JC Braz, BJ Glascock, TF Kimball, ... Molecular and cellular biology, 2002 | 344 | 2002 |
| Regulation of fetal gene expression in heart failure E Dirkx, PA da Costa Martins, LJ De Windt Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 339 | 2013 |
| Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo LJ De Windt, HW Lim, OF Bueno, Q Liang, U Delling, JC Braz, ... Proceedings of the National Academy of Sciences 98 (6), 3322-3327, 2001 | 306 | 2001 |
| MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo DJ Lips, OF Bueno, BJ Wilkins, NH Purcell, RA Kaiser, JN Lorenz, ... Circulation 109 (16), 1938-1941, 2004 | 303 | 2004 |
| Calcineurin promotes protein kinase C and c-Jun NH2-terminal kinase activation in the heart: cross-talk between cardiac hypertrophic signaling pathways LJ De Windt, HW Lim, S Haq, T Force, JD Molkentin Journal of Biological Chemistry 275 (18), 13571-13579, 2000 | 302 | 2000 |
| Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: an apoptosis-independent model of dilated heart failure LJ De Windt, HW Lim, T Taigen, D Wencker, G Condorelli, GW Dorn, ... Circulation research 86 (3), 255-263, 2000 | 298 | 2000 |
| Macrophage microRNA-155 promotes cardiac hypertrophy and failure S Heymans, MF Corsten, W Verhesen, P Carai, REW Van Leeuwen, ... Circulation 128 (13), 1420-1432, 2013 | 292 | 2013 |
| The continuous heart failure spectrum: moving beyond an ejection fraction classification F Triposkiadis, J Butler, FM Abboud, PW Armstrong, S Adamopoulos, ... European heart journal 40 (26), 2155-2163, 2019 | 279 | 2019 |
