متابعة
R.L.H. Spätjens
R.L.H. Spätjens
Maastricht University, Cardiovascular Research Institute Maastricht, Dept. of Cardiology
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عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
Downregulation of delayed rectifier K+ currents in dogs with chronic complete atrioventricular block and acquired torsades de pointes‏
PGA Volders, KR Sipido, MA Vos, RL Spätjens, JDM Leunissen, ...‏
Circulation 100 (24), 2455-2461, 1999‏
3151999
Probing the contribution of IKs to canine ventricular repolarization: key role for β-adrenergic receptor stimulation‏
PGA Volders, M Stengl, JM van Opstal, U Gerlach, RL Spätjens, ...‏
Circulation 107 (21), 2753-2760, 2003‏
2962003
Repolarizing K+ currents ITO1 and IKs are larger in right than left canine ventricular midmyocardium‏
PGA Volders, KR Sipido, E Carmeliet, RL Spätjens, HJJ Wellens, MA Vos‏
Circulation 99 (2), 206-210, 1999‏
2941999
Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes‏
M Stengl, PGA Volders, MB Thomsen, RL Spätjens, KR Sipido, MA Vos‏
The Journal of Physiology 551 (3), 777-786, 2003‏
1252003
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1‏
J Heijman, RL Spätjens, SRM Seyen, V Lentink, HJH Kuijpers, IR Boulet, ...‏
Circulation Research 110 (2), 211-219, 2012‏
842012
Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1‏
J Heijman, RL Spätjens, SR Seyen, V Lentink, HJ Kuijpers, IR Boulet, ...‏
Circulation 124 (Suppl 21), A10189-A10189, 2011‏
842011
Electrophysiological safety of sertindole in dogs with normal and remodeled hearts‏
MB Thomsen, PGA Volders, M Stengl, RL Spätjens, JDM Beekman, ...‏
Journal of Pharmacology and Experimental Therapeutics 307 (2), 776-784, 2003‏
712003
Temporal patterns of electrical remodeling in canine ventricular hypertrophy: Focus on IKs downregulation and blunted β-adrenergic activation‏
M Stengl, C Ramakers, DW Donker, A Nabar, AV Rybin, RL Spätjens, ...‏
Cardiovascular research 72 (1), 90-100, 2006‏
632006
Interventricular Differences in β‐Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases‏
CE Molina, DM Johnson, H Mehel, RL Spätjens, D Mika, V Algalarrondo, ...‏
Journal of the American Heart Association 3 (3), e000858, 2014‏
402014
Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region‏
P Schwartz, C Moreno, MC Kotta, M Pedrazzini, L Crotti, F Dagradi, ...‏
European Heart Journal, 2021‏
362021
Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium‏
DW Donker, JG Maessen, F Verheyen, FC Ramaekers, RL Spätjens, ...‏
American Journal of Physiology-Heart and Circulatory Physiology 292 (5 …, 2007‏
362007
End–diastolic myofiber stress and ejection strain increase with ventricular volume overload: Serial in–vivo analyses in dogs with complete atrioventricular block‏
DW Donker, PGA Volders, T Arts, BCAM Bekkers, L Hofstra, R Spätjens, ...‏
Basic research in cardiology 100, 372-382, 2005‏
362005
Molecular and electrical characterization of the canine cardiac ventricular septum‏
C Ramakers, M Stengl, RL Spätjens, AFM Moorman, MA Vos‏
Journal of molecular and cellular cardiology 38 (1), 153-161, 2005‏
262005
Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers‏
C Altrocchi, T de Korte, J Bernardi, RL Spätjens, SR Braam, J Heijman, ...‏
EP Europace 22 (9), 1431-1441, 2020‏
122020
Long-QT mutation p. K557E-Kv7. 1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation‏
RL Spätjens, M Bébarová, SRM Seyen, V Lentink, RJ Jongbloed, ...‏
Cardiovascular research 104 (1), 216-225, 2014‏
112014
Measurement of Action Potential Generation in Isolated Canine Left Ventricular Midmyocardial Myocytes‏
DM Johnson, L Hussein, RL Spätjens, JP Valentin, PGA Volders, ...‏
Current Protocols in Pharmacology, 2011‏
52011
Electrophysiological and proarrhythmic parameters in transmural canine left-ventricular needle biopsies‏
SC Verduyn, JGM Jungschleger, M Stengl, RL Spätjens, JDM Beekman, ...‏
Pflügers Archiv 449, 115-122, 2004‏
52004
Serial left-ventricular biopsy sampling using a minimally invasive trans-thoracic approach in adult dogs‏
DW Donker, JG Maessen, RL Spätjens, T van der Nagel, M de Jong, ...‏
Pflügers Archiv-European Journal of Physiology 454 (6), 1043-1051, 2007‏
32007
Accumulation of slow delayed rectifier K+ current (I-Ks) in canine ventricular myocytes‏
M Stengl, MA Vos, R Spatjens, KR Sipido, PGA Volders‏
BIOPHYSICAL JOURNAL 82 (1), 606A-606A, 2002‏
22002
Cardiomyocyte cell cycle activity and function is under the control of miR-125a‏
R Verjans, L Braga, M Rech, S Beijnsberger, P Carai, R Spatjens, ...‏
Cardiovascular Research 114 (suppl_1), S18-S18, 2018‏
12018
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مقالات 1–20