| Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP J Xu, P Kurup, Y Zhang, SM Goebel-Goody, PH Wu, AH Hawasli, ... Journal of Neuroscience 29 (29), 9330-9343, 2009 | 346 | 2009 |
| The role of STEP in Alzheimer's disease PJL Pradeep Kurup, Yongfang Zhang, Deepa V Channels (Austin) 4 (5), 347-350, 2010 | 283* | 2010 |
| Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61 LPJ Kurup P, Zhang Y, Xu J, Venkitaramani DV, Haroutunian V, Greengard P ... J Neurosci. 28 (30(17):), 5948-57, 2010 | 260* | 2010 |
| The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation Y Zhang, DV Venkitaramani, CM Gladding, Y Zhang, P Kurup, E Molnar, ... Journal of Neuroscience 28 (42), 10561-10566, 2008 | 217 | 2008 |
| Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model Y Zhang, P Kurup, J Xu, N Carty, SM Fernandez, HB Nygaard, C Pittenger, ... Proceedings of the National Academy of Sciences 107 (44), 19014-19019, 2010 | 209 | 2010 |
| Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders SM Goebel-Goody, M Baum, CD Paspalas, SM Fernandez, NC Carty, ... Pharmacological reviews 64 (1), 65-87, 2012 | 179 | 2012 |
| Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease J Xu, M Chatterjee, TD Baguley, J Brouillette, P Kurup, D Ghosh, J Kanyo, ... PLoS biology 12 (8), e1001923, 2014 | 150 | 2014 |
| Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation DV Venkitaramani, S Paul, Y Zhang, P Kurup, LI Ding, L Tressler, M Allen, ... Synapse 63 (1), 69-81, 2009 | 97 | 2009 |
| Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity J Xu, P Kurup, JA Bartos, T Patriarchi, JW Hell, PJ Lombroso Journal of Biological Chemistry 287 (25), 20942-20956, 2012 | 92 | 2012 |
| The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications NC Carty, J Xu, P Kurup, J Brouillette, SM Goebel-Goody, DR Austin, ... Translational psychiatry 2 (7), e137-e137, 2012 | 91 | 2012 |
| Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase YS Choi, SL Lin, B Lee, P Kurup, HY Cho, JR Naegele, PJ Lombroso, ... Journal of Neuroscience 27 (11), 2999-3009, 2007 | 89 | 2007 |
| Reduced levels of the tyrosine phosphatase STEP block beta amyloid‐mediated GluA1/GluA2 receptor internalization Y Zhang, P Kurup, J Xu, GM Anderson, P Greengard, AC Nairn, ... Journal of neurochemistry 119 (3), 664-672, 2011 | 69 | 2011 |
| STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease. NAC Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ Proc Natl Acad Sci U S A., 2015 | 64* | 2015 |
| Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II R Raveendran, S Devi Suma Priya, M Mayadevi, M Steephan, ... Journal of neurochemistry 110 (1), 92-105, 2009 | 64 | 2009 |
| STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway LPJ Xu J, Kurup P, Foscue E J. Neurochem, 2015 | 46 | 2015 |
| Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models J Xu, BJ Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, ... Molecular psychiatry 23 (2), 271-281, 2018 | 45 | 2018 |
| STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice M Chatterjee, PK Kurup, CJ Lundbye, AKH Toft, J Kwon, J Benedict, ... Neuropharmacology 128, 43-53, 2018 | 38 | 2018 |
| Major vault protein is expressed along the nucleus–neurite axis and associates with mRNAs in cortical neurons CD Paspalas, CC Perley, DV Venkitaramani, SM Goebel-Goody, ... Cerebral Cortex 19 (7), 1666-1677, 2009 | 36 | 2009 |
| Striatal-enriched protein tyrosine phosphatase in Alzheimer’s disease J Xu, P Kurup, AC Nairn, PJ Lombroso Advances in Pharmacology 64, 303-325, 2012 | 34 | 2012 |
| BDNF induces striatal-enriched protein tyrosine phosphatase 61 degradation through the proteasome A Saavedra, M Puigdellívol, S Tyebji, P Kurup, J Xu, S Ginés, J Alberch, ... Molecular neurobiology 53, 4261-4273, 2016 | 33 | 2016 |