Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation PA Jänne, GJ Riely, SM Gadgeel, RS Heist, SHI Ou, JM Pacheco, ... New England Journal of Medicine 387 (2), 120-131, 2022 | 677 | 2022 |
Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC X Le, S Puri, MV Negrao, MB Nilsson, J Robichaux, T Boyle, JK Hicks, ... Clinical Cancer Research 24 (24), 6195-6203, 2018 | 368 | 2018 |
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer MV Negrao, F Skoulidis, M Montesion, K Schulze, I Bara, V Shen, H Xu, ... Journal for immunotherapy of cancer 9 (8), 2021 | 199 | 2021 |
Pan-cancer landscape and analysis of ERBB2 mutations identifies poziotinib as a clinically active inhibitor and enhancer of T-DM1 activity JP Robichaux, YY Elamin, RSK Vijayan, MB Nilsson, L Hu, J He, F Zhang, ... Cancer Cell 36 (4), 444-457. e7, 2019 | 180 | 2019 |
Programmed death-ligand 1 heterogeneity and its impact on benefit from immune checkpoint inhibitors in NSCLC L Hong, MV Negrao, SS Dibaj, R Chen, A Reuben, JM Bohac, X Liu, ... Journal of Thoracic Oncology 15 (9), 1449-1459, 2020 | 159 | 2020 |
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components MB Nilsson, H Sun, J Robichaux, M Pfeifer, U McDermott, J Travers, ... Science translational medicine 12 (559), eaaz4589, 2020 | 140 | 2020 |
Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial T Cascone, CH Leung, A Weissferdt, A Pataer, BW Carter, MCB Godoy, ... Nature medicine 29 (3), 593-604, 2023 | 133 | 2023 |
STING pathway expression identifies NSCLC with an immune-responsive phenotype CM Della Corte, T Sen, CM Gay, K Ramkumar, L Diao, RJ Cardnell, ... Journal of Thoracic Oncology 15 (5), 777-791, 2020 | 125 | 2020 |
OA02. 06 a phase II trial of poziotinib in EGFR and HER2 exon 20 mutant non-small cell lung cancer (NSCLC) J Heymach, M Negrao, J Robichaux, B Carter, A Patel, M Altan, ... Journal of Thoracic Oncology 13 (10), S323-S324, 2018 | 122 | 2018 |
Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC MV Negrao, HA Araujo, G Lamberti, AJ Cooper, NS Akhave, T Zhou, ... Cancer discovery 13 (7), 1556-1571, 2023 | 101 | 2023 |
PD-L1 expression, tumor mutational burden, and cancer gene mutations are stronger predictors of benefit from immune checkpoint blockade than HLA class I genotype in non–small … MV Negrao, VK Lam, A Reuben, ML Rubin, LL Landry, EB Roarty, ... Journal of Thoracic Oncology 14 (6), 1021-1031, 2019 | 101 | 2019 |
Characterization of the immune landscape of EGFR-mutant NSCLC identifies CD73/adenosine pathway as a potential therapeutic target X Le, MV Negrao, A Reuben, L Federico, L Diao, D McGrail, M Nilsson, ... Journal of thoracic oncology 16 (4), 583-600, 2021 | 93 | 2021 |
Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer L Federico, DJ McGrail, SE Bentebibel, C Haymaker, A Ravelli, MA Forget, ... Annals of Oncology 33 (1), 42-56, 2022 | 88 | 2022 |
Poziotinib for Patients With HER2 Exon 20 Mutant Non–Small-Cell Lung Cancer: Results From a Phase II Trial YY Elamin, JP Robichaux, BW Carter, M Altan, DL Gibbons, FV Fossella, ... Journal of Clinical Oncology 40 (7), 702-709, 2022 | 86 | 2022 |
Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity YY Elamin, JP Robichaux, BW Carter, M Altan, H Tran, DL Gibbons, ... Cancer Cell 40 (7), 754-767. e6, 2022 | 83 | 2022 |
Neoadjuvant chemotherapy increases cytotoxic T cell, tissue resident memory T cell, and B cell infiltration in resectable NSCLC PO Gaudreau, MV Negrao, KG Mitchell, A Reuben, EM Corsini, J Li, ... Journal of Thoracic Oncology 16 (1), 127-139, 2021 | 76 | 2021 |
STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition P Sitthideatphaiboon, A Galan-Cobo, MV Negrao, X Qu, A Poteete, ... Clinical Cancer Research 27 (6), 1720-1733, 2021 | 73 | 2021 |
Sequential liquid biopsies reveal dynamic alterations of EGFR driver mutations and indicate EGFR amplification as a new mechanism of resistance to osimertinib in NSCLC FH Knebel, F Bettoni, AK Shimada, M Cruz, JV Alessi, MV Negrão, ... Lung Cancer 108, 238-241, 2017 | 73 | 2017 |
Molecular landscape of BRAF-mutant NSCLC reveals an association between clonality and driver mutations and identifies targetable non-V600 driver mutations MV Negrao, VM Raymond, RB Lanman, JP Robichaux, J He, MB Nilsson, ... Journal of Thoracic Oncology 15 (10), 1611-1623, 2020 | 68 | 2020 |
Surgical outcomes after neoadjuvant nivolumab or nivolumab with ipilimumab in patients with non–small cell lung cancer B Sepesi, N Zhou, WN William Jr, HY Lin, CH Leung, A Weissferdt, ... The Journal of thoracic and cardiovascular surgery 164 (5), 1327-1337, 2022 | 60 | 2022 |