The Nalp3 inflammasome is essential for the development of silicosis SL Cassel, SC Eisenbarth, SS Iyer, JJ Sadler, OR Colegio, LA Tephly, ... Proceedings of the National Academy of Sciences 105 (26), 9035-9040, 2008 | 1066 | 2008 |
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation BH Ye, G Cattoretti, Q Shen, J Zhang, N Hawe, R Waard, C Leung, ... Nature genetics 16 (2), 161-170, 1997 | 1051 | 1997 |
Mechanism and regulation of immunoglobulin isotype switching RL Coffman, DA Lebman, P Rothman Advances in immunology 54, 229-270, 1993 | 698 | 1993 |
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells DK Sojka, B Plougastel-Douglas, L Yang, MA Pak-Wittel, MN Artyomov, ... elife 3, e01659, 2014 | 616 | 2014 |
IL-4/IL-13 signaling beyond Jak/Stat H Jiang, MB Harris, P Rothman Journal of Allergy and Clinical Immunology 105 (6), 1063-1070, 2000 | 473 | 2000 |
TH17 cell differentiation is regulated by the circadian clock X Yu, D Rollins, KA Ruhn, JJ Stubblefield, CB Green, M Kashiwada, ... Science 342 (6159), 727-730, 2013 | 471 | 2013 |
Jak-STAT signaling induced by the v-abl oncogene NN Danial, A Pernis, PB Rothman Science 269 (5232), 1875-1877, 1995 | 446 | 1995 |
Biologic functions of the IFN‐γ receptors G Tau, P Rothman Allergy 54 (12), 1233, 2001 | 400 | 2001 |
Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients. SK Chai, GL Nichols, P Rothman Journal of immunology (Baltimore, Md.: 1950) 159 (10), 4720-4728, 1997 | 373 | 1997 |
Lack of Interferon γ Receptor β Chain and the Prevention of Interferon γ Signaling in TH1 Cells A Pernis, S Gupta, KJ Gollob, E Garfein, RL Coffman, C Schindler, ... Science 269 (5221), 245-247, 1995 | 357 | 1995 |
Mitogen-and IL-4-regulated expression of germ-line Ig γ2b transcripts: evidence for directed heavy chain class switching S Lutzker, P Rothman, R Pollock, R Coffman, FW Alt Cell 53 (2), 177-184, 1988 | 349 | 1988 |
JAK-STAT signaling in asthma AB Pernis, PB Rothman The Journal of clinical investigation 109 (10), 1279-1283, 2002 | 308 | 2002 |
Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome V Staedtke, RY Bai, K Kim, M Darvas, ML Davila, GJ Riggins, ... Nature 564 (7735), 273-277, 2018 | 288 | 2018 |
Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells. P Rothman, S Lutzker, W Cook, R Coffman, FW Alt The Journal of experimental medicine 168 (6), 2385-2389, 1988 | 271 | 1988 |
Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of Iɛ transcription and immunoglobulin E switching MB Harris, CC Chang, MT Berton, NN Danial, J Zhang, D Kuehner, BH Ye, ... Molecular and cellular biology 19 (10), 7264-7275, 1999 | 249 | 1999 |
S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. A Bottaro, R Lansford, L Xu, J Zhang, P Rothman, FW Alt The EMBO journal 13 (3), 665-674, 1994 | 247 | 1994 |
Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction JA Losman, XP Chen, D Hilton, P Rothman The Journal of Immunology 162 (7), 3770-3774, 1999 | 242 | 1999 |
STF‐IL‐4: a novel IL‐4‐induced signal transducing factor. C Schindler, H Kashleva, A Pernis, R Pine, P Rothman The EMBO Journal 13 (6), 1350-1356, 1994 | 241 | 1994 |
Pim serine/threonine kinases regulate the stability of Socs-1 protein XP Chen, JA Losman, S Cowan, E Donahue, S Fay, BQ Vuong, ... Proceedings of the National Academy of Sciences 99 (4), 2175-2180, 2002 | 238 | 2002 |
Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor JJ Ryan, LJ McReynolds, A Keegan, LH Wang, E Garfein, P Rothman, ... Immunity 4 (2), 123-132, 1996 | 226 | 1996 |