متابعة
William R. Sellers
William R. Sellers
Core Institute Member, The Broad Institute
بريد إلكتروني تم التحقق منه على broadinstitute.org
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ...
Science 304 (5676), 1497-1500, 2004
121452004
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
83072012
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
45062010
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
39162005
Gene expression correlates of clinical prostate cancer behavior
D Singh, PG Febbo, K Ross, DG Jackson, J Manola, C Ladd, P Tamayo, ...
Cancer cell 1 (2), 203-209, 2002
32022002
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
28672019
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
LA Garraway, HR Widlund, MA Rubin, G Getz, AJ Berger, S Ramaswamy, ...
Nature 436 (7047), 117-122, 2005
18342005
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17622010
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
17512005
Molecular characterization of the tumor microenvironment in breast cancer
M Allinen, R Beroukhim, L Cai, C Brennan, J Lahti-Domenici, H Huang, ...
Cancer cell 6 (1), 17-32, 2004
15952004
BRAF mutation predicts sensitivity to MEK inhibition
DB Solit, LA Garraway, CA Pratilas, A Sawai, G Getz, A Basso, Q Ye, ...
Nature 439 (7074), 358-362, 2006
15612006
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
H Gao, JM Korn, S Ferretti, JE Monahan, Y Wang, M Singh, C Zhang, ...
Nature medicine 21 (11), 1318-1325, 2015
14542015
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo …
SM Maira, F Stauffer, J Brueggen, P Furet, C Schnell, C Fritsch, ...
Molecular cancer therapeutics 7 (7), 1851-1863, 2008
13712008
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
I Sansal, WR Sellers
Journal of clinical oncology 22 (14), 2954-2963, 2004
12782004
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12602007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11752007
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
PK Majumder, PG Febbo, R Bikoff, R Berger, Q Xue, LM McMahon, ...
Nature medicine 10 (6), 594-601, 2004
11552004
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
WG Kaelin Jr, W Krek, WR Sellers, JA DeCaprio, F Ajchenbaum, ...
Cell 70 (2), 351-364, 1992
10681992
Phosphorylation of the PTEN tail regulates protein stability and function
F Vazquez, S Ramaswamy, N Nakamura, WR Sellers
Molecular and cellular biology 20 (14), 5010-5018, 2000
9602000
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
ME McMenamin, P Soung, S Perera, I Kaplan, M Loda, WR Sellers
Cancer research 59 (17), 4291-4296, 1999
9311999
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مقالات 1–20