| Top-down proteomics: ready for prime time? B Chen, KA Brown, Z Lin, Y Ge Analytical chemistry 90 (1), 110-127, 2017 | 221 | 2017 |
| Novel strategies to address the challenges in top-down proteomics JA Melby, DS Roberts, EJ Larson, KA Brown, EF Bayne, S Jin, Y Ge Journal of the American Society for Mass Spectrometry 32 (6), 1278-1294, 2021 | 165 | 2021 |
| Top-down proteomics: challenges, innovations, and applications in basic and clinical research KA Brown, JA Melby, DS Roberts, Y Ge Expert review of proteomics 17 (10), 719-733, 2020 | 134 | 2020 |
| Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry M Zhou, C Lantz, KA Brown, Y Ge, L Paša-Tolić, JA Loo, F Lermyte Chemical science 11 (48), 12918-12936, 2020 | 124 | 2020 |
| A photocleavable surfactant for top-down proteomics KA Brown, B Chen, TM Guardado-Alvarez, Z Lin, L Hwang, S Ayaz-Guner, ... Nature methods 16 (5), 417-420, 2019 | 100 | 2019 |
| Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1, 3, 8-Triazaspiro [4.5] decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in … MC O’Reilly, SA Scott, KA Brown, TH Oguin III, PG Thomas, JS Daniels, ... Journal of medicinal chemistry 56 (6), 2695-2699, 2013 | 72 | 2013 |
| Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum TN Tiambeng, DS Roberts, KA Brown, Y Zhu, B Chen, Z Wu, SD Mitchell, ... Nature Communications 11 (1), 3903, 2020 | 63 | 2020 |
| Ultrafast and reproducible proteomics from small amounts of heart tissue enabled by Azo and timsTOF pro TJ Aballo, DS Roberts, JA Melby, KM Buck, KA Brown, Y Ge Journal of Proteome Research 20 (8), 4203-4211, 2021 | 57 | 2021 |
| Exploring a 2-Naphthoic Acid Template for the Structure-Based Design of P2Y14 Receptor Antagonist Molecular Probes E Kiselev, MO Barrett, V Katritch, S Paoletta, CD Weitzer, KA Brown, ... ACS chemical biology 9 (12), 2833-2842, 2014 | 50 | 2014 |
| High‐throughput proteomics enabled by a photocleavable surfactant KA Brown, T Tucholski, C Eken, S Knott, Y Zhu, S Jin, Y Ge Angewandte Chemie 132 (22), 8484-8488, 2020 | 46 | 2020 |
| Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists A Junker, R Balasubramanian, A Ciancetta, E Uliassi, E Kiselev, ... Journal of Medicinal Chemistry 59 (13), 6149-6168, 2016 | 46 | 2016 |
| Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes SA Scott, CT Spencer, MC O’Reilly, KA Brown, RR Lavieri, CH Cho, ... ACS chemical biology 10 (2), 421-432, 2015 | 45 | 2015 |
| High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms JA Melby, KA Brown, ZR Gregorich, DS Roberts, EA Chapman, LE Ehlers, ... Proceedings of the National Academy of Sciences 120 (19), e2222081120, 2023 | 37 | 2023 |
| Bridged hybrid monolithic column coupled to high-resolution mass spectrometry for top-down proteomics Y Liang, Y Jin, Z Wu, T Tucholski, KA Brown, L Zhang, Y Zhang, Y Ge Analytical chemistry 91 (3), 1743-1747, 2019 | 35 | 2019 |
| Top-down proteomics of endogenous membrane proteins enabled by cloud point enrichment and multidimensional liquid chromatography–mass spectrometry KA Brown, T Tucholski, AJ Alpert, C Eken, L Wesemann, A Kyrvasilis, ... Analytical chemistry 92 (24), 15726-15735, 2020 | 32 | 2020 |
| Photocleavable surfactant-enabled extracellular matrix proteomics SJ Knott, KA Brown, H Josyer, A Carr, D Inman, S Jin, A Friedl, SM Ponik, ... Analytical chemistry 92 (24), 15693-15698, 2020 | 27 | 2020 |
| Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor E Kiselev, R Balasubramanian, E Uliassi, KA Brown, K Trujillo, V Katritch, ... Bioorganic & medicinal chemistry letters 25 (21), 4733-4739, 2015 | 25 | 2015 |
| Comparing top-down proteoform identification: deconvolution, PrSM overlap, and PTM detection DL Tabb, K Jeong, K Druart, MS Gant, KA Brown, C Nicora, M Zhou, ... Journal of Proteome Research 22 (7), 2199-2217, 2023 | 24 | 2023 |
| 4-Alkyloxyimino derivatives of uridine-5′-triphosphate: distal modification of potent agonists as a strategy for molecular probes of P2Y2, P2Y4, and P2Y6 receptors PS Jayasekara, MO Barrett, CB Ball, KA Brown, E Hammes, ... Journal of Medicinal Chemistry 57 (9), 3874-3883, 2014 | 24 | 2014 |
| MASH Native: a unified solution for native top-down proteomics data processing EJ Larson, MR Pergande, ME Moss, KJ Rossler, RK Wenger, B Krichel, ... Bioinformatics 39 (6), btad359, 2023 | 18 | 2023 |