| Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes D Perera, RC Poulos, A Shah, D Beck, JE Pimanda, JWH Wong Nature 532 (7598), 259-263, 2016 | 249 | 2016 |
| Machine learning for multi-omics data integration in cancer Z Cai, RC Poulos, J Liu, Q Zhong Iscience 25 (2), 2022 | 149 | 2022 |
| Pan-cancer proteomic map of 949 human cell lines E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ... Cancer cell 40 (8), 835-849. e8, 2022 | 135 | 2022 |
| WDR5 supports an N-Myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma Y Sun, JL Bell, D Carter, S Gherardi, RC Poulos, G Milazzo, JWH Wong, ... Cancer research 75 (23), 5143-5154, 2015 | 121 | 2015 |
| Strategies to enable large-scale proteomics for reproducible research RC Poulos, PG Hains, R Shah, N Lucas, D Xavier, SS Manda, A Anees, ... Nature communications 11 (1), 3793, 2020 | 117 | 2020 |
| The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes RC Poulos, J Olivier, JWH Wong Nucleic acids research 45 (13), 7786-7795, 2017 | 91 | 2017 |
| Functional mutations form at CTCF-cohesin binding sites in melanoma due to uneven nucleotide excision repair across the motif RC Poulos, JAI Thoms, YF Guan, A Unnikrishnan, JE Pimanda, ... Cell reports 17 (11), 2865-2872, 2016 | 90 | 2016 |
| The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription M Wong, AEL Tee, G Milazzo, JL Bell, RC Poulos, B Atmadibrata, Y Sun, ... Cancer Research 77 (9), 2522-2533, 2017 | 85 | 2017 |
| JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma M Wong, Y Sun, Z Xi, G Milazzo, RC Poulos, C Bartenhagen, JL Bell, ... Nature communications 10 (1), 3319, 2019 | 82 | 2019 |
| Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia D Jing, Y Huang, X Liu, KCS Sia, JC Zhang, X Tai, M Wang, CE Toscan, ... Cancer cell 34 (6), 906-921. e8, 2018 | 77 | 2018 |
| Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations RC Poulos, YT Wong, R Ryan, H Pang, JWH Wong PLoS genetics 14 (11), e1007779, 2018 | 58 | 2018 |
| Role of POT1 in human cancer Y Wu, RC Poulos, RR Reddel Cancers 12 (10), 2739, 2020 | 56 | 2020 |
| Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer H Fang, JA Barbour, RC Poulos, R Katainen, LA Aaltonen, JWH Wong PLoS genetics 16 (2), e1008572, 2020 | 30 | 2020 |
| Systematic Screening of Promoter Regions Pinpoints Functional Cis-Regulatory Mutations in a Cutaneous Melanoma Genome RC Poulos, JAI Thoms, A Shah, D Beck, JE Pimanda, JWH Wong Molecular Cancer Research 13 (8), 1218-1226, 2015 | 30 | 2015 |
| OncoCis: annotation of cis-regulatory mutations in cancer D Perera, D Chacon, JAI Thoms, RC Poulos, A Shlien, D Beck, ... Genome biology 15, 1-14, 2014 | 28 | 2014 |
| Finding cancer driver mutations in the era of big data research RC Poulos, JWH Wong Biophysical reviews 11 (1), 21-29, 2019 | 26 | 2019 |
| The search for cis-regulatory driver mutations in cancer genomes RC Poulos, MA Sloane, LB Hesson, JWH Wong Oncotarget 6 (32), 32509, 2015 | 22 | 2015 |
| Opportunities for pharmacoproteomics in biomarker discovery RC Poulos, Z Cai, PJ Robinson, RR Reddel, Q Zhong Proteomics 23 (7-8), 2200031, 2023 | 20 | 2023 |
| Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation MJ Morris, LB Hesson, RC Poulos, RL Ward, JWH Wong, NA Youngson Biomarker research 6, 1-8, 2018 | 18 | 2018 |
| Disruption of a −35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells Q Liu, JAI Thoms, AC Nunez, Y Huang, K Knezevic, D Packham, ... Clinical Cancer Research 24 (18), 4602-4611, 2018 | 15 | 2018 |