An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 729 | 2019 |
Genetic drivers of epigenetic and transcriptional variation in human immune cells L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ... Cell 167 (5), 1398-1414. e24, 2016 | 717 | 2016 |
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis JP Kemp, JA Morris, C Medina-Gomez, V Forgetta, NM Warrington, ... Nature genetics 49 (10), 1468-1475, 2017 | 468 | 2017 |
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study K Trajanoska, JA Morris, L Oei, HF Zheng, DM Evans, DP Kiel, C Ohlsson, ... bmj 362, 2018 | 272* | 2018 |
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness SM Willems, DJ Wright, FR Day, K Trajanoska, PK Joshi, JA Morris, ... Nature communications 8 (1), 16015, 2017 | 203 | 2017 |
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease OS Ahmad, JA Morris, M Mujammami, V Forgetta, A Leong, R Li, ... Nature communications 6 (1), 7060, 2015 | 144 | 2015 |
Genetically decreased vitamin D and risk of Alzheimer disease LE Mokry, S Ross, JA Morris, D Manousaki, V Forgetta, JB Richards Neurology 87 (24), 2567-2574, 2016 | 136 | 2016 |
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens JA Morris, C Caragine, Z Daniloski, J Domingo, T Barry, L Lu, K Davis, ... Science 380 (6646), eadh7699, 2023 | 122* | 2023 |
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ... Nature communications 12 (1), 2444, 2021 | 98 | 2021 |
Development of a polygenic risk score to improve screening for fracture risk: a genetic risk prediction study V Forgetta, J Keller-Baruch, M Forest, A Durand, S Bhatnagar, JP Kemp, ... PLoS medicine 17 (7), e1003152, 2020 | 86* | 2020 |
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps V Iotchkova, J Huang, JA Morris, D Jain, C Barbieri, K Walter, JL Min, ... Nature genetics 48 (11), 1303-1312, 2016 | 79 | 2016 |
A Mendelian randomization study of the effect of type‐2 diabetes and glycemic traits on bone mineral density OS Ahmad, A Leong, JA Miller, JA Morris, V Forgetta, M Mujammami, ... Journal of Bone and Mineral Research 32 (5), 1072-1081, 2017 | 66 | 2017 |
Metabolomic pathways to osteoporosis in middle‐aged women: a genome‐metabolome‐wide Mendelian randomization study A Moayyeri, CL Cheung, KCB Tan, JA Morris, A Cerani, RP Mohney, ... Journal of Bone and Mineral Research 33 (4), 643-650, 2018 | 64 | 2018 |
Epigenome‐wide association of DNA methylation in whole blood with bone mineral density JA Morris, PC Tsai, R Joehanes, J Zheng, K Trajanoska, M Soerensen, ... Journal of Bone and Mineral Research 32 (8), 1644-1650, 2017 | 64 | 2017 |
Childhood obesity and multiple sclerosis: A Mendelian randomization study A Harroud, RE Mitchell, TG Richardson, JA Morris, V Forgetta, ... Multiple Sclerosis Journal 27 (14), 2150-2158, 2021 | 59 | 2021 |
Genome-wide association study of extreme high bone mass: contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes CL Gregson, F Newell, PJ Leo, GR Clark, L Paternoster, M Marshall, ... Bone 114, 62-71, 2018 | 59 | 2018 |
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq HH Wessels, A Méndez-Mancilla, Y Hao, E Papalexi, WM Mauck III, L Lu, ... Nature methods 20 (1), 86-94, 2023 | 53 | 2023 |
An effector index to predict target genes at GWAS loci V Forgetta, L Jiang, NA Vulpescu, MS Hogan, S Chen, JA Morris, S Grinek, ... Human Genetics 141 (8), 1431-1447, 2022 | 52* | 2022 |
FAM210A is a novel determinant of bone and muscle structure and strength K Tanaka, Y Xue, L Nguyen-Yamamoto, JA Morris, I Kanazawa, ... Proceedings of the National Academy of Sciences 115 (16), E3759-E3768, 2018 | 51 | 2018 |
SCEPTRE improves calibration and sensitivity in single-cell CRISPR screen analysis T Barry, X Wang, JA Morris, K Roeder, E Katsevich Genome biology 22, 1-19, 2021 | 46 | 2021 |