The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance KC Schreck, P Taylor, L Marchionni, V Gopalakrishnan, EE Bar, N Gaiano, ... Clinical cancer research 16 (24), 6060-6070, 2010 | 202 | 2010 |
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation X Su, V Gopalakrishnan, D Stearns, K Aldape, FF Lang, G Fuller, ... Molecular and cellular biology 26 (5), 1666-1678, 2006 | 188 | 2006 |
MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ... Molecular cell 70 (5), 825-841. e6, 2018 | 141 | 2018 |
Valproic acid induces p21 and topoisomerase-II (α/β) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines CM Das, D Aguilera, H Vasquez, P Prasad, M Zhang, JE Wolff, ... Journal of neuro-oncology 85 (2), 159-170, 2007 | 134 | 2007 |
Conversion of myoblasts to physiologically active neuronal phenotype Y Watanabe, S Kameoka, V Gopalakrishnan, KD Aldape, ZZ Pan, ... Genes & development 18 (8), 889-900, 2004 | 112 | 2004 |
E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication V Gopalakrishnan, SA Khan Proceedings of the National Academy of Sciences 91 (20), 9597, 1994 | 89 | 1994 |
Redundant control of rereplication in fission yeast V Gopalakrishnan, P Simancek, C Houchens, HA Snaith, MG Frattini, ... Proceedings of the National Academy of Sciences 98 (23), 13114, 2001 | 83 | 2001 |
Phase I study of intraventricular infusions of autologous ex vivo expanded NK cells in children with recurrent medulloblastoma and ependymoma S Khatua, LJN Cooper, DI Sandberg, L Ketonen, JM Johnson, ME Rytting, ... Neuro-oncology 22 (8), 1214-1225, 2020 | 77 | 2020 |
Measuring cytotoxicity: a new perspective on LC50 M ZHANG, D AGUILERA, C DAS, H VASQUEZ, P ZAGE, ... Anticancer research 27 (1A), 35-38, 2007 | 76 | 2007 |
REST and the RESTless: in stem cells and beyond V Gopalakrishnan Future neurology 4 (3), 317-329, 2009 | 71 | 2009 |
Influence of valproic acid on outcome of high-grade gliomas in children A MASOUDI, M ELOPRE, E AMINI, ME NAGEL, JL ATER, ... Anticancer research 28 (4C), 2437-2442, 2008 | 70 | 2008 |
REST is a novel prognostic factor and therapeutic target for medulloblastoma P Taylor, J Fangusaro, V Rajaram, S Goldman, IB Helenowski, ... Molecular cancer therapeutics 11 (8), 1713-1723, 2012 | 67 | 2012 |
Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCFβ‐TRCP in neuroblastoma cells A Singh, C Rokes, M Gireud, S Fletcher, J Baumgartner, G Fuller, ... Cancer, 2011 | 67 | 2011 |
Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma CP Bailey, M Figueroa, A Gangadharan, Y Yang, MM Romero, BA Kennis, ... Neuro-oncology 22 (9), 1302-1314, 2020 | 61 | 2020 |
Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL DG Aguilera, CM Das, ND Sinnappah-Kang, C Joyce, PH Taylor, S Wen, ... Journal of neuro-oncology 93 (3), 303-318, 2009 | 53 | 2009 |
The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation CM Das, P Taylor, M Gireud, A Singh, D Lee, G Fuller, L Ji, J Fangusaro, ... Oncogene, 2012 | 52 | 2012 |
p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma AW Currier, EA Kolb, RG Gorlick, ME Roth, V Gopalakrishnan, ... Scientific reports 9 (1), 6161, 2019 | 38 | 2019 |
Monitoring of intracerebellarly-administered natural killer cells with fluorine-19 MRI BA Kennis, KA Michel, WB Brugmann, A Laureano, RH Tao, ... Journal of neuro-oncology 142, 395-407, 2019 | 37 | 2019 |
Regulation of USP37 Expression by REST-Associated G9a-Dependent Histone Methylation THW Dobson, RJ Hatcher, J Swaminathan, CM Das, S Shaik, RH Tao, ... Molecular Cancer Research 15 (8), 1073-1084, 2017 | 37 | 2017 |
Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration K Callegari, S Maegawa, J Bravo-Alegria, V Gopalakrishnan Cell Communication and Signaling 16, 1-13, 2018 | 34 | 2018 |