3′ end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells L Davidson, L Muniz, S West Genes & development 28 (4), 342-356, 2014 | 187 | 2014 |
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity JD Eaton, L Davidson, DLV Bauer, T Natsume, MT Kanemaki, S West Genes & development 32 (2), 127-139, 2018 | 147 | 2018 |
A unified allosteric/torpedo mechanism for transcriptional termination on human protein-coding genes JD Eaton, L Francis, L Davidson, S West Genes & development 34 (1-2), 132-145, 2020 | 139 | 2020 |
Co‐transcriptional degradation of aberrant pre‐mRNA by Xrn2 L Davidson, A Kerr, S West The EMBO journal 31 (11), 2566-2578, 2012 | 112 | 2012 |
Rapid depletion of DIS3, EXOSC10, or XRN2 reveals the immediate impact of exoribonucleolysis on nuclear RNA metabolism and transcriptional control L Davidson, L Francis, RA Cordiner, JD Eaton, C Estell, S Macias, ... Cell reports 26 (10), 2779-2791. e5, 2019 | 84 | 2019 |
Poly (A) polymerase and the nuclear poly (A) binding protein, PABPN1, coordinate the splicing and degradation of a subset of human pre-mRNAs L Muniz, L Davidson, S West Molecular and cellular biology 35 (13), 2218-2230, 2015 | 57 | 2015 |
ZC3H4 restricts non-coding transcription in human cells C Estell, L Davidson, PC Steketee, A Monier, S West Elife 10, e67305, 2021 | 44 | 2021 |
Splicing-coupled 3′ end formation requires a terminal splice acceptor site, but not intron excision L Davidson, S West Nucleic acids research 41 (14), 7101-7114, 2013 | 34 | 2013 |
A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription C Estell, L Davidson, JD Eaton, H Kimura, VAM Gold, S West Molecular cell 83 (13), 2222-2239. e5, 2023 | 27 | 2023 |
Integrator-dependent and allosteric/intrinsic mechanisms ensure efficient termination of snRNA transcription L Davidson, L Francis, JD Eaton, S West Cell reports 33 (4), 2020 | 27 | 2020 |
DNA-directed termination of mammalian RNA polymerase II L Davidson, JO Rouvière, R Sousa-Luís, T Nojima, NJ Proudfoot, ... Genes & Development 38 (21-24), 998-1019, 2024 | 4 | 2024 |
Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9 JD Eaton, J Board, L Davidson, C Estell, S West Elife 13, RP92764, 2024 | 2 | 2024 |
Nuclear Surveillance Pathways Play a Key Role in Regulating the Transcription Landscape of Eukaryotic Genomes LG Davidson University of Sheffield, 2018 | | 2018 |