The Sac1 Domain of SYNJ1 Identified Mutated in a Family with Early‐Onset Progressive Parkinsonism with Generalized Seizures CE Krebs, S Karkheiran, JC Powell, M Cao, V Makarov, H Darvish, ... Human mutation 34 (9), 1200-1207, 2013 | 384 | 2013 |
[29] Human plasminogen FJ Castellino, JR Powell Methods in Enzymology 80, 365-378, 1981 | 291 | 1981 |
Targeted gene knockout mediated by triple helix forming oligonucleotides A Majumdar, A Khorlin, N Dyatkina, FLM Lin, J Powell, J Liu, Z Fei, ... Nature genetics 20 (2), 212-214, 1998 | 249 | 1998 |
Parkinson's disease-associated LRRK2 hyperactive kinase mutant disrupts synaptic vesicle trafficking in ventral midbrain neurons PY Pan, X Li, J Wang, J Powell, Q Wang, Y Zhang, Z Chen, B Wicinski, ... Journal of Neuroscience 37 (47), 11366-11376, 2017 | 146 | 2017 |
Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide PP Chan, M Lin, AF Faruqi, J Powell, MM Seidman, PM Glazer Journal of Biological Chemistry 274 (17), 11541-11548, 1999 | 139 | 1999 |
The existence of independent domain structures in human Lys77-plasminogen. FJ Castellino, VA Ploplis, JR Powell, DK Strickland Journal of Biological Chemistry 256 (10), 4778-4782, 1981 | 117 | 1981 |
Development and clinical application of an integrative genomic approach to personalized cancer therapy AV Uzilov, W Ding, MY Fink, Y Antipin, AS Brohl, C Davis, CY Lau, ... Genome Medicine 8 (62), 1-20, 2016 | 105 | 2016 |
A novel framework for characterizing genomic haplotype diversity in the human immunoglobulin heavy chain locus OL Rodriguez, WS Gibson, T Parks, M Emery, J Powell, M Strahl, ... Frontiers in immunology 11, 2136, 2020 | 86 | 2020 |
Interleukin-1 receptor type 1 is a substrate for γ-secretase-dependent regulated intramembrane proteolysis BM Elzinga, C Twomey, JC Powell, F Harte, JV McCarthy Journal of Biological Chemistry 284 (3), 1394-1409, 2009 | 72 | 2009 |
Activation of human neo-plasminogen-Val442 by urokinase and streptokinase and a kinetic characterization of neoplasmin-Val442. JR Powell, FJ Castellino Journal of Biological Chemistry 255 (11), 5329-5335, 1980 | 70 | 1980 |
Interactions among stomata in response to perturbations in humidity KA Mott, F Denne, J Powell Plant, Cell & Environment 20 (9), 1098-1107, 1997 | 69 | 1997 |
Amplification-free, CRISPR-Cas9 targeted enrichment and SMRT sequencing of repeat-expansion disease causative genomic regions YC Tsai, D Greenberg, J Powell, I Höijer, A Ameur, M Strahl, E Ellis, ... BioRxiv, 203919, 2017 | 68 | 2017 |
The insulin-like growth factor 1 (IGF-1) receptor is a substrate for γ-secretase-mediated intramembrane proteolysis B McElroy, JC Powell, JV McCarthy Biochemical and biophysical research communications 358 (4), 1136-1141, 2007 | 67 | 2007 |
The EphA3 receptor is expressed in a subset of rhabdomyosarcoma cell lines and suppresses cell adhesion and migration ROC Noretta Clifford, Loraine M. Smith, James Powell, Stefan Gattenlöhner ... Journal of Cellular Biochemistry 105 (Issue 5), Pages 1250–1259, 2008 | 48 | 2008 |
Role of the lysine binding regions in the kinetic properties of human plasmin JP Morris, S Blatt, JR Powell, DK Strickland, FJ Castellino Biochemistry 20 (17), 4811-4816, 1981 | 46 | 1981 |
Association between Presenilin‐1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor JC Powell, C Twomey, R Jain, JV McCarthy Journal of neurochemistry 108 (1), 216-230, 2009 | 45 | 2009 |
γ-Secretase activity is required for regulated intramembrane proteolysis of tumor necrosis factor (TNF) receptor 1 and TNF-mediated pro-apoptotic signaling J Chhibber-Goel, C Coleman-Vaughan, V Agrawal, N Sawhney, E Hickey, ... Journal of Biological Chemistry 291 (11), 5971-5985, 2016 | 43 | 2016 |
Amino acid sequence analysis of the asparagine-288 region of the carbohydrate variants of human plasminogen JR Powell, FJ Castellino Biochemistry 22 (4), 923-927, 1983 | 43 | 1983 |
Synthesis of a methylenebis (phosphonate) analogue of mycophenolic adenine dinucleotide: A glucuronidation-resistant MAD analogue of NAD K Lesiak, KA Watanabe, A Majumdar, J Powell, M Seidman, ... Journal of medicinal chemistry 41 (4), 618-622, 1998 | 37 | 1998 |
Human single nucleotide polymorphisms Z Tsuchihashi, L Hui, K Zerba, M Ma-Edmonds, M Perrone, B Swanson, ... US Patent App. 10/005,956, 2003 | 31 | 2003 |