An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 715 | 2019 |
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis JP Kemp, JA Morris, C Medina-Gomez, V Forgetta, NM Warrington, ... Nature genetics 49 (10), 1468-1475, 2017 | 468 | 2017 |
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 360 | 2021 |
Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma MM McDonald, MR Reagan, SE Youlten, ST Mohanty, A Seckinger, ... Blood, The Journal of the American Society of Hematology 129 (26), 3452-3464, 2017 | 183 | 2017 |
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease SE Youlten, JP Kemp, JG Logan, EJ Ghirardello, CM Sergio, MRG Dack, ... Nature communications 12 (1), 2444, 2021 | 98 | 2021 |
Accelerating functional gene discovery in osteoarthritis NC Butterfield, KF Curry, J Steinberg, H Dewhurst, D Komla-Ebri, ... Nature communications 12 (1), 467, 2021 | 60 | 2021 |
Genome-wide association study of extreme high bone mass: contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes CL Gregson, F Newell, PJ Leo, GR Clark, L Paternoster, M Marshall, ... Bone 114, 62-71, 2018 | 59 | 2018 |
A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for … CL Gregson, DJM Bergen, P Leo, RB Sessions, L Wheeler, A Hartley, ... Journal of Bone and Mineral Research 35 (1), 92-105, 2020 | 44 | 2020 |
Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease DJM Bergen, Q Tong, A Shukla, E Newham, J Zethof, M Lundberg, ... Bmc Biology 20 (1), 21, 2022 | 36 | 2022 |
Neutrophil conversion to a tumor-killing phenotype underpins effective microbial therapy AO Yam, J Bailey, F Lin, A Jakovija, SE Youlten, C Counoupas, M Gunzer, ... Cancer Research 83 (8), 1315-1328, 2023 | 18 | 2023 |
Single-cell multi-modal GAN reveals spatial patterns in single-cell data from triple-negative breast cancer M Amodio, SE Youlten, A Venkat, BP San Juan, CL Chaffer, ... Patterns 3 (9), 2022 | 17 | 2022 |
An atlas of human and murine genetic influences on osteoporosis JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, R Chai, ... bioRxiv, 338863, 2018 | 15 | 2018 |
Library adaptors with integrated reference controls improve the accuracy and reliability of nanopore sequencing HM Gunter, SE Youlten, BS Madala, ALM Reis, I Stevanovski, T Wong, ... Nature Communications 13 (1), 6437, 2022 | 9 | 2022 |
Me Research T JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani …, 2019 | 9 | 2019 |
Osteocytes express a unique transcriptome that underpins skeletal homeostasis. S Youlten, P Baldock, V Leitch, J Quinn, N Bartonicek, R Chai, J Eisman, ... JOURNAL OF BONE AND MINERAL RESEARCH 32, S55-S56, 2017 | 9 | 2017 |
Using mouse genetics to understand human skeletal disease SE Youlten, PA Baldock Bone 126, 27-36, 2019 | 7 | 2019 |
spARC recovers human glioma spatial signaling networks with graph filtering M Kuchroo, DF Miyagishima, HR Steach, A Godavarthi, Y Takeo, PQ Duy, ... bioRxiv, 2022.08. 24.505139, 2022 | 4 | 2022 |
AAnet resolves a continuum of spatially-localized cell states to unveil tumor complexity A Venkat, SE Youlten, BPS Juan, C Purcell, M Amodio, DB Burkhardt, ... bioRxiv, 2024.05. 11.593705, 2024 | 2 | 2024 |
Mapping the gene space at single-cell resolution with gene signal pattern analysis A Venkat, S Leone, SE Youlten, E Fagerberg, J Attanasio, NS Joshi, ... Nature Computational Science 4 (12), 955-977, 2024 | 1 | 2024 |
A universal molecular control for DNA, mRNA and protein expression HM Gunter, SE Youlten, ALM Reis, T McCubbin, BS Madala, T Wong, ... Nature Communications 15 (1), 2480, 2024 | 1 | 2024 |