| U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation D Kaida, MG Berg, I Younis, M Kasim, LN Singh, L Wan, G Dreyfuss nature 468 (7324), 664-668, 2010 | 709 | 2010 |
| U1 snRNP determines mRNA length and regulates isoform expression MG Berg, LN Singh, I Younis, Q Liu, AM Pinto, D Kaida, Z Zhang, S Cho, ... Cell 150 (1), 53-64, 2012 | 529 | 2012 |
| Comprehensive multi-omics analysis reveals mitochondrial stress as a central biological hub for spaceflight impact WA da Silveira, H Fazelinia, SB Rosenthal, EC Laiakis, MS Kim, ... Cell 183 (5), 1185-1201. e20, 2020 | 286 | 2020 |
| Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes JJ Johnston, WS Rubinstein, FM Facio, D Ng, LN Singh, JK Teer, ... The American Journal of Human Genetics 91 (1), 97-108, 2012 | 222 | 2012 |
| Mitochondrial DNA variation and cancer PK Kopinski, LN Singh, S Zhang, MT Lott, DC Wallace Nature Reviews Cancer 21 (7), 431-445, 2021 | 200 | 2021 |
| Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy Z Zhang, AM Pinto, L Wan, W Wang, MG Berg, I Oliva, LN Singh, ... Proceedings of the National Academy of Sciences 110 (48), 19348-19353, 2013 | 198 | 2013 |
| Host mitochondria influence gut microbiome diversity: A role for ROS T Yardeni, CE Tanes, K Bittinger, LM Mattei, PM Schaefer, LN Singh, ... Science signaling 12 (588), eaaw3159, 2019 | 155 | 2019 |
| The landscape of transcription errors in eukaryotic cells JF Gout, W Li, C Fritsch, A Li, S Haroon, L Singh, D Hua, H Fazelinia, ... Science advances 3 (10), e1701484, 2017 | 154 | 2017 |
| Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy PK Kopinski, KA Janssen, PM Schaefer, S Trefely, CE Perry, P Potluri, ... Proceedings of the National Academy of Sciences 116 (32), 16028-16035, 2019 | 151 | 2019 |
| Specifications of the ACMG/AMP standards and guidelines for mitochondrial DNA variant interpretation EM McCormick, MT Lott, MC Dulik, L Shen, M Attimonelli, O Vitale, ... Human mutation 41 (12), 2028-2057, 2020 | 129 | 2020 |
| Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts JW Guarnieri, JM Dybas, H Fazelinia, MS Kim, J Frere, Y Zhang, ... Science translational medicine 15 (708), eabq1533, 2023 | 112 | 2023 |
| Interpreting secondary cardiac disease variants in an exome cohort D Ng, JJ Johnston, JK Teer, LN Singh, LC Peller, JS Wynter, KL Lewis, ... Circulation: Cardiovascular Genetics 6 (4), 337-346, 2013 | 100 | 2013 |
| CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features K Essien, S Vigneau, S Apreleva, LN Singh, MS Bartolomei, ... Genome biology 10, 1-15, 2009 | 99 | 2009 |
| Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations JJ Johnston, KL Lewis, D Ng, LN Singh, J Wynter, C Brewer, BP Brooks, ... The American Journal of Human Genetics 96 (6), 913-925, 2015 | 83 | 2015 |
| Role of miR-2392 in driving SARS-CoV-2 infection JT McDonald, FJ Enguita, D Taylor, RJ Griffin, W Priebe, MR Emmett, ... Cell reports 37 (3), 2021 | 81 | 2021 |
| Association between mitochondrial DNA haplogroup variation and autism spectrum disorders D Chalkia, LN Singh, J Leipzig, M Lvova, O Derbeneva, A Lakatos, ... JAMA psychiatry 74 (11), 1161-1168, 2017 | 71 | 2017 |
| The pediatric cell atlas: defining the growth phase of human development at single-cell resolution DM Taylor, BJ Aronow, K Tan, K Bernt, N Salomonis, CS Greene, ... Developmental cell 49 (1), 10-29, 2019 | 69 | 2019 |
| Assessing the reproducibility of exome copy number variations predictions CS Hong, LN Singh, JC Mullikin, LG Biesecker Genome medicine 8, 1-11, 2016 | 67 | 2016 |
| Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression LN Singh, S Hannenhalli PLoS One 3 (6), e2345, 2008 | 43 | 2008 |
| Altering the mitochondrial fatty acid synthesis (mtFASII) pathway modulates cellular metabolic states and bioactive lipid profiles as revealed by metabolomic profiling HB Clay, AK Parl, SL Mitchell, L Singh, LN Bell, DG Murdock PloS one 11 (3), e0151171, 2016 | 42 | 2016 |
