| A single-cell transcriptomic map of the human and mouse pancreas reveals inter-and intra-cell population structure M Baron, A Veres, SL Wolock, AL Faust, R Gaujoux, A Vetere, JH Ryu, ... Cell systems 3 (4), 346-360. e4, 2016 | 1407 | 2016 |
| Target identification and mechanism of action in chemical biology and drug discovery M Schenone, V Dančík, BK Wagner, PA Clemons Nature chemical biology 9 (4), 232-240, 2013 | 1276 | 2013 |
| Correlating chemical sensitivity and basal gene expression reveals mechanism of action MG Rees, B Seashore-Ludlow, JH Cheah, DJ Adams, EV Price, S Gill, ... Nature chemical biology 12 (2), 109-116, 2016 | 807 | 2016 |
| A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ... Nature communications 10 (1), 1617, 2019 | 721 | 2019 |
| Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles PA Clemons, NE Bodycombe, HA Carrinski, JA Wilson, AF Shamji, ... Proceedings of the National Academy of Sciences 107 (44), 18787-18792, 2010 | 366 | 2010 |
| A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy SG Deeks, B Wagner, PA Anton, RT Mitsuyasu, DT Scadden, C Huang, ... Molecular Therapy 5 (6), 788-797, 2002 | 366 | 2002 |
| Targeting the pancreatic β-cell to treat diabetes A Vetere, A Choudhary, SM Burns, BK Wagner Nature reviews Drug discovery 13 (4), 278-289, 2014 | 343 | 2014 |
| Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs DJ Adams, M Dai, G Pellegrino, BK Wagner, AM Stern, AF Shamji, ... Proceedings of the National Academy of Sciences 109 (38), 15115-15120, 2012 | 252 | 2012 |
| Inhibition of DYRK1A stimulates human β-cell proliferation E Dirice, D Walpita, A Vetere, BC Meier, S Kahraman, J Hu, V Dančík, ... Diabetes 65 (6), 1660-1671, 2016 | 235 | 2016 |
| Large-scale chemical dissection of mitochondrial function BK Wagner, T Kitami, TJ Gilbert, D Peck, A Ramanathan, SL Schreiber, ... Nature biotechnology 26 (3), 343-351, 2008 | 231 | 2008 |
| A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9 B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ... Cell 177 (4), 1067-1079. e19, 2019 | 198 | 2019 |
| An expanded universe of cancer targets WC Hahn, JS Bader, TP Braun, A Califano, PA Clemons, BJ Druker, ... Cell 184 (5), 1142-1155, 2021 | 187 | 2021 |
| A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma Y Yuan, Q Wang, J Paulk, S Kubicek, MM Kemp, DJ Adams, AF Shamji, ... ACS chemical biology 7 (7), 1152-1157, 2012 | 182 | 2012 |
| Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ... Cell 170 (1), 199-212. e20, 2017 | 172 | 2017 |
| A one-bead, one-stock solution approach to chemical genetics: part 2 PA Clemons, AN Koehler, BK Wagner, TG Sprigings, DR Spring, RW King, ... Chemistry & Biology 8 (12), 1183-1195, 2001 | 135 | 2001 |
| The power of sophisticated phenotypic screening and modern mechanism-of-action methods BK Wagner, SL Schreiber Cell chemical biology 23 (1), 3-9, 2016 | 115 | 2016 |
| High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function SM Burns, A Vetere, D Walpita, V Dančík, C Khodier, J Perez, ... Cell metabolism 21 (1), 126-137, 2015 | 114 | 2015 |
| Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections PA Clemons, JA Wilson, V Dančík, S Muller, HA Carrinski, BK Wagner, ... Proceedings of the National Academy of Sciences 108 (17), 6817-6822, 2011 | 111 | 2011 |
| Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis DHC Chou, EB Holson, FF Wagner, AJ Tang, RL Maglathlin, TA Lewis, ... Chemistry & biology 19 (6), 669-673, 2012 | 110 | 2012 |
| Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation Z Arany, BK Wagner, Y Ma, J Chinsomboon, D Laznik, BM Spiegelman Proceedings of the National Academy of Sciences 105 (12), 4721-4726, 2008 | 109 | 2008 |