| Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade N Nakamoto, H Cho, A Shaked, K Olthoff, ME Valiga, M Kaminski, ... PLoS pathogens 5 (2), e1000313, 2009 | 471 | 2009 |
| Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis N Nakamoto, N Sasaki, R Aoki, K Miyamoto, W Suda, T Teratani, T Suzuki, ... Nature microbiology 4 (3), 492-503, 2019 | 383 | 2019 |
| Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization N Nakamoto, DE Kaplan, J Coleclough, Y Li, ME Valiga, M Kaminski, ... Gastroenterology 134 (7), 1927-1937. e2, 2008 | 370 | 2008 |
| Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection H Ebinuma, N Nakamoto, Y Li, DA Price, E Gostick, BL Levine, J Tobias, ... Journal of virology 82 (10), 5043-5053, 2008 | 206 | 2008 |
| The liver–brain–gut neural arc maintains the Treg cell niche in the gut T Teratani, Y Mikami, N Nakamoto, T Suzuki, Y Harada, K Okabayashi, ... Nature 585 (7826), 591-596, 2020 | 190 | 2020 |
| Role of toll-like receptors in immune activation and tolerance in the liver N Nakamoto, T Kanai Frontiers in immunology 5, 221, 2014 | 182 | 2014 |
| Efficacy of non-invasive elastometry on staging of hepatic fibrosis H Saito, S Tada, N Nakamoto, K Kitamura, H Horikawa, S Kurita, Y Saito, ... Hepatology research 29 (2), 97-103, 2004 | 165 | 2004 |
| Evaluation of liver fibrosis by transient elastography using acoustic radiation force impulse: comparison with Fibroscan® H Ebinuma, H Saito, M Komuta, K Ojiro, K Wakabayashi, S Usui, P Chu, ... Journal of gastroenterology 46, 1238-1248, 2011 | 158 | 2011 |
| CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells Y Koda, T Teratani, PS Chu, Y Hagihara, Y Mikami, Y Harada, ... Nature communications 12 (1), 4474, 2021 | 149 | 2021 |
| Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice R Aoki, M Onuki, K Hattori, M Ito, T Yamada, K Kamikado, YG Kim, ... Microbiome 9, 1-16, 2021 | 109 | 2021 |
| C‐C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice P Chu, N Nakamoto, H Ebinuma, S Usui, K Saeki, A Matsumoto, Y Mikami, ... Hepatology 58 (1), 337-350, 2013 | 109 | 2013 |
| A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury N Nakamoto, S Tada, K Kameyama, K Kitamura, S Kurita, Y Saito, H Saito, ... Free Radical Research 37 (8), 849-859, 2003 | 102 | 2003 |
| Glycolytic pathway affects differentiation of human monocytes to regulatory macrophages H Suzuki, T Hisamatsu, S Chiba, K Mori, MT Kitazume, K Shimamura, ... Immunology letters 176, 18-27, 2016 | 92 | 2016 |
| Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis DE Kaplan, F Ikeda, Y Li, N Nakamoto, S Ganesan, ME Valiga, FA Nunes, ... Journal of hepatology 48 (6), 903-913, 2008 | 90 | 2008 |
| CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis N Nakamoto, H Ebinuma, T Kanai, PS Chu, Y Ono, Y Mikami, K Ojiro, ... Gastroenterology 142 (2), 366-376, 2012 | 87 | 2012 |
| Commensal Lactobacillus controls immune tolerance during acute liver injury in mice N Nakamoto, T Amiya, R Aoki, N Taniki, Y Koda, K Miyamoto, T Teratani, ... Cell reports 21 (5), 1215-1226, 2017 | 83 | 2017 |
| Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor M Nakamura, H Saito, H Ebinuma, K Wakabayashi, Y Saito, T Takagi, ... Journal of Cellular Physiology 187 (3), 392-401, 2001 | 76 | 2001 |
| On-treatment decrease of NKG2D correlates to early emergence of clinically evident hepatocellular carcinoma after interferon-free therapy for chronic hepatitis C P Chu, N Nakamoto, N Taniki, K Ojiro, T Amiya, Y Makita, H Murata, ... PloS one 12 (6), e0179096, 2017 | 70 | 2017 |
| Autoimmune hepatitis in Japan: trends in a nationwide survey A Takahashi, T Arinaga-Hino, H Ohira, T Torimura, M Zeniya, M Abe, ... Journal of gastroenterology 52, 631-640, 2017 | 69 | 2017 |
| Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis K Kitamura, S Tada, N Nakamoto, K Toda, H Horikawa, S Kurita, ... Journal of gastroenterology and hepatology 22 (11), 2022-2033, 2007 | 67 | 2007 |
