Nucleosidic DNA demethylating epigenetic drugs–a comprehensive review from discovery to clinic K Agrawal, V Das, P Vyas, M Hajdúch Pharmacology & therapeutics 188, 45-79, 2018 | 151 | 2018 |
Pathophysiologically relevant in vitro tumor models for drug screening V Das, F Bruzzese, P Konečný, F Iannelli, A Budillon, M Hajduch Drug discovery today 20 (7), 848-855, 2015 | 67 | 2015 |
Metallacarborane sulfamides: Unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX B Grüner, J Brynda, V Das, V Šícha, J Štěpánková, J Nekvinda, ... Journal of Medicinal Chemistry 62 (21), 9560-9575, 2019 | 65 | 2019 |
Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid‐induced Tau phosphorylation V Das, JH Miller European Journal of Neuroscience 35 (11), 1705-1717, 2012 | 55 | 2012 |
Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer’s disease N Annadurai, K Agrawal, P Džubák, M Hajdúch, V Das Cellular and molecular life sciences 74, 4159-4169, 2017 | 45 | 2017 |
Reproducibility of uniform spheroid formation in 384-well plates: The effect of medium evaporation V Das, T Fürst, S Gurská, P Džubák, M Hajdúch Journal of biomolecular screening 21 (9), 923-930, 2016 | 39 | 2016 |
Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies N Annadurai, JB De Sanctis, M Hajdúch, V Das Experimental neurology 343, 113756, 2021 | 33 | 2021 |
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX J Dvořanová, M Kugler, J Holub, V Šícha, V Das, J Nekvinda, S El Anwar, ... European Journal of Medicinal Chemistry 200, 112460, 2020 | 33 | 2020 |
Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs V Das, J Štěpánková, M Hajdúch, JH Miller Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 172-182, 2015 | 33 | 2015 |
Inhibitors of CA IX enzyme based on polyhedral boron compounds M Kugler, J Nekvinda, J Holub, S El Anwar, V Das, V Šícha, K Pospíšilová, ... ChemBioChem 22 (18), 2741-2761, 2021 | 31 | 2021 |
Effect of taxoid and nontaxoid site microtubule‐stabilizing agents on axonal transport of mitochondria in untransfected and ECFP‐htau40‐transfected rat cortical neurons in culture V Das, DA Sim, JH Miller Journal of Neuroscience Research 92 (9), 1155-1166, 2014 | 27 | 2014 |
Potential role of tubulin tyrosine ligase-like enzymes in tumorigenesis and cancer cell resistance V Das, A Kanakkanthara, A Chan, JH Miller Cancer letters 350 (1-2), 1-4, 2014 | 21 | 2014 |
Non-taxoid site microtubule-stabilizing drugs work independently of tau overexpression in mouse N2a neuroblastoma cells V Das, JH Miller Brain research 1489, 121-132, 2012 | 18 | 2012 |
Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation N Annadurai, L Malina, J Malohlava, M Hajdúch, V Das Biochimie 200, 79-86, 2022 | 17 | 2022 |
Antitumour drugs targeting tau R3 VQIVYK and Cys322 prevent seeding of endogenous tau aggregates by exogenous seeds N Annadurai, L Malina, M Salmona, L Diomede, A Bastone, A Cagnotto, ... The FEBS journal 289 (7), 1929-1949, 2022 | 17 | 2022 |
Potential for treatment of neurodegenerative diseases with natural products or synthetic compounds that stabilize microtubules JH Miller, V Das Current Pharmaceutical Design 26 (35), 4362-4372, 2020 | 17 | 2020 |
Triterpenoid pyrazines and pyridines–synthesis, cytotoxicity, mechanism of action, preparation of prodrugs J Hodoň, I Frydrych, Z Trhlíková, J Pokorný, L Borková, S Benická, M Vlk, ... European Journal of Medicinal Chemistry 243, 114777, 2022 | 16 | 2022 |
Nucleoside-based anticancer drugs: Mechanism of action and drug resistance L Hruba, V Das, M Hajduch, P Dzubak Biochemical Pharmacology 215, 115741, 2023 | 10 | 2023 |
Evaporation-reducing culture condition increases the reproducibility of multicellular spheroid formation in microtiter plates V Das, T Fürst, S Gurská, P Džubák, M Hajdúch Journal of Visualized Experiments: JoVE, 55403, 2017 | 10 | 2017 |
Cell‐based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models K Agrawal, V Das, M Otmar, M Krečmerová, P Džubák, M Hajdúch Cytometry Part A 91 (2), 133-143, 2017 | 10 | 2017 |