A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 596 | 2021 |
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations S Affo, A Nair, F Brundu, A Ravichandra, S Bhattacharjee, M Matsuda, ... Cancer cell 39 (6), 866-882. e11, 2021 | 313 | 2021 |
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts S Bhattacharjee, F Hamberger, A Ravichandra, M Miller, A Nair, S Affo, ... The Journal of clinical investigation 131 (11), 2024 | 259 | 2024 |
Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandra, ... Nature 610 (7931), 356-365, 2022 | 188 | 2022 |
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome H Su, F Yang, R Fu, B Trinh, N Sun, J Liu, A Kumar, J Baglieri, J Siruno, ... Nature 610 (7931), 366-372, 2022 | 113 | 2022 |
Brain invasion by mouse hepatitis virus depends on impairment of tight junctions and beta interferon production in brain microvascular endothelial cells C Bleau, A Filliol, M Samson, L Lamontagne Journal of virology 89 (19), 9896-9908, 2015 | 96 | 2015 |
RIPK1 protects from TNF-α-mediated liver damage during hepatitis A Filliol, C Piquet-Pellorce, J Le Seyec, M Farooq, V Genet, C Lucas-Clerc, ... Cell death & disease 7 (11), e2462-e2462, 2016 | 80 | 2016 |
Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis MF Fondevila, U Fernandez, V Heras, T Parracho, MJ Gonzalez-Rellan, ... Journal of hepatology 77 (1), 15-28, 2022 | 62 | 2022 |
RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis A Filliol, C Piquet-Pellorce, C Raguénès-Nicol, S Dion, M Farooq, ... Journal of hepatology 66 (6), 1205-1213, 2017 | 62 | 2017 |
A therapeutic silencing RNA targeting hepatocyte TAZ prevents and reverses fibrosis in nonalcoholic steatohepatitis in mice X Wang, MR Sommerfeld, K Jahn‐Hofmann, B Cai, A Filliol, HE Remotti, ... Hepatology Communications 3 (9), 1221-1234, 2019 | 51 | 2019 |
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver I Mederacke, A Filliol, S Affo, A Nair, C Hernandez, Q Sun, F Hamberger, ... Science translational medicine 14 (639), eabe5795, 2022 | 50 | 2022 |
Contributions of fibroblasts, extracellular matrix, stiffness, and mechanosensing to hepatocarcinogenesis A Filliol, RF Schwabe Seminars in Liver Disease 39 (03), 315-333, 2019 | 43 | 2019 |
A therapeutically targetable TAZ-TEAD2 pathway drives the growth of hepatocellular carcinoma via ANLN and KIF23 Y Saito, D Yin, N Kubota, X Wang, A Filliol, H Remotti, A Nair, L Fazlollahi, ... Gastroenterology 164 (7), 1279-1292, 2023 | 40 | 2023 |
The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulate IL-33 expression in liver MI Arshad, C Piquet-Pellorce, A Filliol, A L’Helgoualc’h, C Lucas-Clerc, ... Journal of molecular medicine 93, 867-878, 2015 | 38 | 2015 |
Sibiriline, a new small chemical inhibitor of receptor‐interacting protein kinase 1, prevents immune‐dependent hepatitis F Le Cann, C Delehouzé, S Leverrier‐Penna, A Filliol, A Comte, ... The FEBS journal 284 (18), 3050-3068, 2017 | 32 | 2017 |
Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration G Noel, MI Arshad, A Filliol, V Genet, M Rauch, C Lucas-Clerc, A Lehuen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (2 …, 2016 | 26 | 2016 |
Endogenous IL-33 has no effect on the progression of fibrosis during experimental steatohepatitis P Vasseur, S Dion, A Filliol, V Genet, C Lucas-Clerc, G Jean-Philippe, ... Oncotarget 8 (30), 48563, 2017 | 23 | 2017 |
Mouse hepatitis virus infection induces a toll-like receptor 2-dependent activation of inflammatory functions in liver sinusoidal endothelial cells during acute hepatitis C Bleau, A Filliol, M Samson, L Lamontagne Journal of virology 90 (20), 9096-9113, 2016 | 23 | 2016 |
Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis M Farooq, A Filliol, M Simoes Eugénio, C Piquet-Pellorce, S Dion, ... Cell death & disease 10 (1), 12, 2019 | 22 | 2019 |
FoxM1 induces CCl2 secretion from hepatocytes triggering hepatic inflammation, injury, fibrosis, and liver cancer A Filliol, RF Schwabe Cellular and molecular gastroenterology and hepatology 9 (3), 555-556, 2020 | 20 | 2020 |