| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13579* | 2021 |
| Extension of life-span with superoxide dismutase/catalase mimetics S Melov, J Ravenscroft, S Malik, MS Gill, DW Walker, PE Clayton, ... Science 289 (5484), 1567-1569, 2000 | 1212 | 2000 |
| Autophagy as a promoter of longevity: insights from model organisms M Hansen, DC Rubinsztein, DW Walker Nature reviews Molecular cell biology 19 (9), 579-593, 2018 | 786 | 2018 |
| Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila M Rera, RI Clark, DW Walker Proceedings of the National Academy of Sciences 109 (52), 21528-21533, 2012 | 618 | 2012 |
| Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog M Rera, S Bahadorani, J Cho, CL Koehler, M Ulgherait, JH Hur, ... Cell metabolism 14 (5), 623-634, 2011 | 490 | 2011 |
| Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality RI Clark, A Salazar, R Yamada, S Fitz-Gibbon, M Morselli, J Alcaraz, ... Cell reports 12 (10), 1656-1667, 2015 | 480 | 2015 |
| Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain JM Copeland, J Cho, T Lo, JH Hur, S Bahadorani, T Arabyan, J Rabie, ... Current Biology 19 (19), 1591-1598, 2009 | 468 | 2009 |
| Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan A Rana, M Rera, DW Walker Proceedings of the National Academy of Sciences 110 (21), 8638-8643, 2013 | 345 | 2013 |
| AMPK modulates tissue and organismal aging in a non-cell-autonomous manner M Ulgherait, A Rana, M Rera, J Graniel, DW Walker Cell reports 8 (6), 1767-1780, 2014 | 296 | 2014 |
| Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster A Rana, MP Oliveira, AV Khamoui, R Aparicio, M Rera, HB Rossiter, ... Nature communications 8 (1), 448, 2017 | 281 | 2017 |
| Evolution of lifespan in C. elegans DW Walker, G McColl, NL Jenkins, J Harris, GJ Lithgow Nature 405 (6784), 296-297, 2000 | 251 | 2000 |
| Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods D GuhaThakurta, L Palomar, GD Stormo, P Tedesco, TE Johnson, ... Genome research 12 (5), 701-712, 2002 | 211 | 2002 |
| MEF2 is an in vivo immune-metabolic switch RI Clark, SWS Tan, CB Péan, U Roostalu, V Vivancos, K Bronda, ... Cell 155 (2), 435-447, 2013 | 183 | 2013 |
| Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan DW Walker, J Muffat, C Rundel, S Benzer Current Biology 16 (7), 674-679, 2006 | 154 | 2006 |
| Mitochondrial “swirls” induced by oxygen stress and in the Drosophila mutant hyperswirl DW Walker, S Benzer Proceedings of the National Academy of Sciences 101 (28), 10290-10295, 2004 | 149 | 2004 |
| Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila J Muffat, DW Walker, S Benzer Proceedings of the National Academy of Sciences 105 (19), 7088-7093, 2008 | 138 | 2008 |
| Upregulation of the autophagy adaptor p62/SQSTM1 prolongs health and lifespan in middle-aged Drosophila R Aparicio, A Rana, DW Walker Cell reports 28 (4), 1029-1040. e5, 2019 | 119 | 2019 |
| Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant DW Walker, P Hájek, J Muffat, D Knoepfle, S Cornelison, G Attardi, ... Proceedings of the National Academy of Sciences 103 (44), 16382-16387, 2006 | 118 | 2006 |
| Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis M Resnik-Docampo, CL Koehler, RI Clark, JM Schinaman, V Sauer, ... Nature cell biology 19 (1), 52-59, 2017 | 116 | 2017 |
| Role of gut microbiota in aging-related health decline: insights from invertebrate models RI Clark, DW Walker Cellular and molecular life sciences 75 (1), 93-101, 2018 | 110 | 2018 |