Connecting copper and cancer: from transition metal signalling to metalloplasia EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross, GM DeNicola, QP Dou, ... Nature Reviews Cancer 22 (2), 102-113, 2022 | 913 | 2022 |
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 797 | 2013 |
Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA X Wang, RD Paucek, AR Gooding, ZZ Brown, EJ Ge, TW Muir, TR Cech Nature structural & molecular biology 24 (12), 1028-1038, 2017 | 237 | 2017 |
Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes N Mashtalir, HT Dao, A Sankar, H Liu, AJ Corin, JD Bagert, EJ Ge, ... Science 373 (6552), 306-315, 2021 | 98 | 2021 |
Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase KS Jani, SU Jain, EJ Ge, KL Diehl, SM Lundgren, MM Müller, PW Lewis, ... Proceedings of the National Academy of Sciences 116 (17), 8295-8300, 2019 | 96 | 2019 |
Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates JDW Toh, SWM Crossley, KJ Bruemmer, EJ Ge, D He, DA Iovan, ... Proceedings of the National Academy of Sciences 117 (41), 25284-25292, 2020 | 72 | 2020 |
Temporally controlled targeting of 4-hydroxynonenal to specific proteins in living cells X Fang, Y Fu, MJC Long, JA Haegele, EJ Ge, S Parvez, Y Aye Journal of the American Chemical Society 135 (39), 14496-14499, 2013 | 71 | 2013 |
PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor KL Diehl, EJ Ge, DN Weinberg, KS Jani, CD Allis, TW Muir Proceedings of the National Academy of Sciences 116 (44), 22152-22157, 2019 | 40 | 2019 |
Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin R Leicher, EJ Ge, X Lin, MJ Reynolds, W Xie, T Walz, B Zhang, TW Muir, ... Proceedings of the National Academy of Sciences 117 (48), 30465-30475, 2020 | 38 | 2020 |
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism VN Pham, KJ Bruemmer, JDW Toh, EJ Ge, L Tenney, CC Ward, ... Science 382 (6670), eabp9201, 2023 | 29 | 2023 |
Nucleation and propagation of heterochromatin by the histone methyltransferase PRC2: geometric constraints and impact of the regulatory subunit JARID2 EJ Ge, KS Jani, KL Diehl, MM Müller, TW Muir Journal of the American Chemical Society 141 (38), 15029-15039, 2019 | 22 | 2019 |
RNA nanoparticles for targeted therapies of triple-negative breast cancers L Danai, E Ge, KA Afonin Molecular Therapy-Nucleic Acids 33, 885-886, 2023 | 1 | 2023 |
Use of Designer Chromatin Substrates for Mechanistic Studies of the Histone Methyltransferase PRC2 JG Eva Princeton University, 2019 | | 2019 |