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Exosomal S100A4 derived from highly metastatic hepatocellular carcinoma cells promotes metastasis by activating STAT3 H Sun, C Wang, B Hu, X Gao, T Zou, Q Luo, M Chen, Y Fu, Y Sheng, ... Signal transduction and targeted therapy 6 (1), 187, 2021 | 88 | 2021 |
Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin J Song, Z Ge, X Yang, Q Luo, C Wang, H You, T Ge, Y Deng, H Lin, Y Cui, ... Cancer letters 356 (2), 713-720, 2015 | 87 | 2015 |
GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling WL Chen, X Jin, M Wang, D Liu, Q Luo, H Tian, L Cai, L Meng, R Bi, ... Jci Insight 5 (3), e131596, 2020 | 82 | 2020 |
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells Q Luo, CQ Wang, LY Yang, XM Gao, HT Sun, Y Zhang, KL Zhang, Y Zhu, ... Cancer letters 417, 21-34, 2018 | 81 | 2018 |
LIFR functions as a metastasis suppressor in hepatocellular carcinoma by negatively regulating phosphoinositide 3-kinase/AKT pathway Q Luo, C Wang, G Jin, D Gu, N Wang, J Song, H Jin, F Hu, Y Zhang, T Ge, ... Carcinogenesis 36 (10), 1201-1212, 2015 | 69 | 2015 |
Aldehyde dehydrogenase 2 activation ameliorates CCl4‐induced chronic liver fibrosis in mice by up‐regulating Nrf2/HO‐1 antioxidant pathway X Ma, Q Luo, H Zhu, X Liu, Z Dong, K Zhang, Y Zou, J Wu, J Ge, A Sun Journal of cellular and molecular medicine 22 (8), 3965-3978, 2018 | 62 | 2018 |
Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of β-Catenin Y Zheng, C Zhou, XX Yu, C Wu, HL Jia, XM Gao, JM Yang, CQ Wang, ... Cell death & disease 9 (2), 179, 2018 | 62 | 2018 |
Clusterin facilitates metastasis by EIF3I/Akt/MMP13 signaling in hepatocellular carcinoma C Wang, G Jin, H Jin, N Wang, Q Luo, Y Zhang, D Gao, K Jiang, D Gu, ... Oncotarget 6 (5), 2903, 2014 | 61 | 2014 |
Interleukin-6 enhances cancer stemness and promotes metastasis of hepatocellular carcinoma via up-regulating osteopontin expression CQ Wang, HT Sun, XM Gao, N Ren, YY Sheng, Z Wang, Y Zheng, JW Wei, ... American journal of cancer research 6 (9), 1873, 2016 | 59 | 2016 |
Hypoxia upregulates Rab11-family interacting protein 4 through HIF-1α to promote the metastasis of hepatocellular carcinoma F Hu, X Deng, X Yang, H Jin, D Gu, X Lv, C Wang, Y Zhang, X Huo, ... Oncogene 34 (49), 6007-6017, 2015 | 59 | 2015 |
Osteopontin alters DNA methylation through up-regulating DNMT1 and sensitizes CD133+/CD44+ cancer stem cells to 5 azacytidine in hepatocellular carcinoma X Gao, Y Sheng, J Yang, C Wang, R Zhang, Y Zhu, Z Zhang, K Zhang, ... Journal of Experimental & Clinical Cancer Research 37, 1-14, 2018 | 54 | 2018 |
A targetable molecular chaperone Hsp27 confers aggressiveness in hepatocellular carcinoma Y Zhang, X Tao, G Jin, H Jin, N Wang, F Hu, Q Luo, H Shu, F Zhao, M Yao, ... Theranostics 6 (4), 558, 2016 | 54 | 2016 |
Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors X Lv, X Lu, J Cao, Q Luo, Y Ding, F Peng, A Pataer, D Lu, D Han, ... Science 381 (6662), eabn4180, 2023 | 44 | 2023 |
The asialoglycoprotein receptor suppresses the metastasis of hepatocellular carcinoma via LASS2-mediated inhibition of V-ATPase activity D Gu, H Jin, G Jin, C Wang, N Wang, F Hu, Q Luo, W Chu, M Yao, W Qin Cancer letters 379 (1), 107-116, 2016 | 40 | 2016 |
LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells Y Zhang, Q Luo, N Wang, F Hu, H Jin, T Ge, C Wang, W Qin Medical oncology 32, 1-10, 2015 | 39 | 2015 |
The dual blockade of MET and VEGFR2 signaling demonstrates pronounced inhibition on tumor growth and metastasis of hepatocellular carcinoma Y Zhang, X Gao, Y Zhu, D Kadel, H Sun, J Chen, Q Luo, H Sun, L Yang, ... Journal of Experimental & Clinical Cancer Research 37, 1-15, 2018 | 36 | 2018 |
Hepatitis B virus X protein co-activates pregnane X receptor to induce the cytochrome P450 3A4 enzyme, a potential implication in hepatocarcinogenesis Y Niu, Z Wu, Q Shen, J Song, Q Luo, H You, G Shi, W Qin Digestive and Liver Disease 45 (12), 1041-1048, 2013 | 33 | 2013 |