| Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models A Palomer, F Cabré, J Pascual, J Campos, MA Trujillo, A Entrena, ... Journal of medicinal chemistry 45 (7), 1402-1411, 2002 | 291 | 2002 |
| Choline kinase inhibitors as a novel approach for antiproliferative drug design R Hernández-Alcoceba, L Saniger, J Campos, MC Núñez, F Khaless, ... Oncogene 15 (19), 2289-2301, 1997 | 217 | 1997 |
| Homochiral drugs: a demanding tendency of the pharmaceutical industry MC Nunez, ME Garcia-Rubino, A Conejo-Garcia, O Cruz-Lopez, ... Current medicinal chemistry 16 (16), 2064-2074, 2009 | 131 | 2009 |
| Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells A Rodríguez-González, AR De Molina, F Fernandez, MA Ramos, ... Oncogene 22 (55), 8803-8812, 2003 | 110 | 2003 |
| The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells MA García, E Carrasco, M Aguilera, P Alvarez, C Rivas, JM Campos, ... PLoS One 6 (8), e23887, 2011 | 78 | 2011 |
| Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line R Sánchez-Martín, JM Campos, A Conejo-García, O Cruz-López, ... Journal of medicinal chemistry 48 (9), 3354-3363, 2005 | 75 | 2005 |
| An in silico study of the antioxidant ability for two caffeine analogs using molecular docking and quantum chemical methods JS Costa, RS Ramos, KSL Costa, DSB Brasil, CHTP Silva, EFB Ferreira, ... Molecules 23 (11), 2801, 2018 | 72 | 2018 |
| Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors O Cruz-Lopez, A Conejo-Garcia, M C Nunez, M Kimatrai, ... Current medicinal chemistry 18 (7), 943-963, 2011 | 72 | 2011 |
| Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells JC Lacal, JM Campos Molecular cancer therapeutics 14 (1), 31-39, 2015 | 71 | 2015 |
| Synthesis of tetrahydrobenzoxazepine acetals with electron-withdrawing groups on the nitrogen atom. Novel scaffolds endowed with anticancer activity against breast cancer cells M Díaz-Gavilán, F Rodríguez-Serrano, JA Gómez-Vidal, JA Marchal, ... Tetrahedron 60 (50), 11547-11557, 2004 | 65 | 2004 |
| Identification of potential COX-2 inhibitors for the treatment of inflammatory diseases using molecular modeling approaches PHF Araújo, RS Ramos, JN da Cruz, SG Silva, EFB Ferreira, LR de Lima, ... Molecules 25 (18), 4183, 2020 | 64 | 2020 |
| Growth inhibition, G1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives JA Marchal, H Boulaiz, I Suárez, E Saniger, J Campos, E Carrillo, ... Investigational new drugs 22, 379-389, 2004 | 62 | 2004 |
| Synthesis, biological activity, and quantitative structure− activity relationship study of azanaphthalimide and arylnaphthalimide derivatives MF Brana, A Gradillas, A Gómez, N Acero, F Llinares, D Munoz-Mingarro, ... Journal of medicinal chemistry 47 (9), 2236-2242, 2004 | 62 | 2004 |
| In silico study to identify new antituberculosis molecules from natural sources by hierarchical virtual screening and molecular dynamics simulations VS Pinto, JSC Araújo, RC Silva, GV da Costa, JN Cruz, MF De A. Neto, ... Pharmaceuticals 12 (1), 36, 2019 | 60 | 2019 |
| Identification of potential inhibitors from pyriproxyfen with insecticidal activity by virtual screening R da Silva Ramos, J da Silva Costa, R Campos Silva, G Vilhena da Costa, ... Pharmaceuticals 12 (1), 20, 2019 | 59 | 2019 |
| Imidazoles and benzimidazoles as tubulin-modulators for anti-cancer therapy FC Torres, M Eugenia Garcia-Rubino, C Lozano-Lopez, DF Kawano, ... Current Medicinal Chemistry 22 (11), 1312-1323, 2015 | 55 | 2015 |
| Identification of novel chemical entities for adenosine receptor type 2a using molecular modeling approaches KLB Santos, JN Cruz, LB Silva, RS Ramos, MFA Neto, CC Lobato, ... Molecules 25 (5), 1245, 2020 | 54 | 2020 |
| New (RS)-benzoxazepin-purines with antitumour activity: the chiral switch from (RS)-2, 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1, 2, 3, 5-tetrahydro-4, 1-benzoxazepin-3-yl]-9H … LC López-Cara, A Conejo-García, JA Marchal, G Macchione, ... European Journal of Medicinal Chemistry 46 (1), 249-258, 2011 | 54 | 2011 |
| Anticancer activity of (1, 2, 3, 5-tetrahydro-4, 1-benzoxazepine-3-yl)-pyrimidines and-purines against the MCF-7 cell line: preliminary cDNA microarray studies M Díaz-Gavilán, JA Gómez-Vidal, F Rodríguez-Serrano, JA Marchal, ... Bioorganic & Medicinal Chemistry Letters 18 (4), 1457-1460, 2008 | 52 | 2008 |
| A New Systematization of the Conformational Behavior of Seven-Membered Rings. Isoclinal Anomeric and Related Orientations1 A Entrena, J Campos, JA Gómez, MA Gallo, A Espinosa The Journal of Organic Chemistry 62 (2), 337-349, 1997 | 52 | 1997 |
