Следене
David Gallo
David Gallo
Repare Therapeutics
Потвърден имейл адрес: reparerx.com
Заглавие
Позовавания
Позовавания
Година
HELB is a feedback inhibitor of DNA end resection
J Tkáč, G Xu, H Adhikary, JTF Young, D Gallo, C Escribano-Díaz, ...
Molecular cell 61 (3), 405-418, 2016
1722016
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
D Gallo, JTF Young, J Fourtounis, G Martino, A Álvarez-Quilón, C Bernier, ...
Nature 604 (7907), 749-756, 2022
1412022
Haploinsufficiency of an RB–E2F1–Condensin II complex leads to aberrant replication and aneuploidy
CH Coschi, CA Ishak, D Gallo, A Marshall, S Talluri, J Wang, MJ Cecchini, ...
Cancer discovery 4 (7), 840-853, 2014
882014
A role for USP7 in DNA replication
M Jagannathan, T Nguyen, D Gallo, N Luthra, GW Brown, V Saridakis, ...
Molecular and cellular biology 34 (1), 132-145, 2014
872014
Rad5 recruits error-prone DNA polymerases for mutagenic repair of ssDNA gaps on undamaged templates
D Gallo, TH Kim, B Szakal, X Saayman, A Narula, Y Park, D Branzei, ...
Molecular cell 73 (5), 900-914. e9, 2019
652019
Assembly of Slx4 signaling complexes behind DNA replication forks
A Balint, TH Kim, D Gallo, JR Cussiol, FM Bastos de Oliveira, A Yimit, J Ou, ...
The EMBO journal 34 (16), 2182-2197, 2015
542015
Comparative chemogenomics to examine the mechanism of action of DNA-targeted platinum-acridine anticancer agents
K Cheung-Ong, KT Song, Z Ma, D Shabtai, AY Lee, D Gallo, LE Heisler, ...
ACS chemical biology 7 (11), 1892-1901, 2012
502012
Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner
JR Becker, D Gallo, W Leung, T Croissant, YM Thu, HD Nguyen, TK Starr, ...
Nucleic acids research 46 (11), 5634-5650, 2018
482018
Analysis of replicating yeast chromosomes by DNA combing
D Gallo, G Wang, CM Yip, GW Brown
Cold Spring Harbor Protocols 2016 (2), pdb. prot085118, 2016
372016
Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer
D Gallo, GW Brown
Critical reviews in biochemistry and molecular biology 54 (3), 301-332, 2019
242019
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma
L Tamayo-Orrego, D Gallo, F Racicot, A Bemmo, S Mohan, B Ho, ...
Nature cancer 1 (8), 840-854, 2020
232020
Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle
L Sansregret, D Gallo, M Santaguida, L Leduy, R Harada, A Nepveu
Journal of Biological Chemistry 285 (43), 32834-32843, 2010
192010
Haploinsufficiency of an RB-E2F1-Condensin II complex leads to aberrant replication and aneuploidy. Cancer Discov. 2014; 4: 840–853. doi: 10.1158/2159-8290
CH Coschi, CA Ishak, D Gallo, A Marshall, S Talluri, J Wang, MJ Cecchini, ...
CD-14-0215.[Abstract][CrossRef][Academic Search], 0
6
Single-molecule analysis of replicating yeast chromosomes
D Gallo, G Wang, CM Yip, GW Brown
Cold Spring Harbor Protocols 2016 (2), pdb. top077784, 2016
42016
Fanconi anemia signaling and Mus81 cooperate to safeguard development and crosslink repair
M Larin, D Gallo, L Tamblyn, J Yang, H Liao, N Sabat, GW Brown, ...
Nucleic acids research 42 (15), 9807-9820, 2014
42014
CDK12 loss leads to replication stress and sensitivity to combinations of the ATR inhibitor camonsertib (RP-3500) with PARP inhibitors
J Setton, D Gallo, D Glodzik, B Kaiser, S Braverman, T Ubhi, S Fournier, ...
European Journal of Cancer 174, S99-S100, 2022
32022
Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR
H Xu, E George, D Gallo, S Medvedev, X Wang, R Kryczka, ML Hyer, ...
Research Square, rs. 3. rs-3854682, 2024
22024
Preclinical development of PKMYT1 and WEE1 inhibitor combinations
D Gallo, F Shah, R Stocco, C Bernier, J Fourtounis, A Shiwram, R Kryczka, ...
Molecular Cancer Therapeutics 22 (12), 2023
22023
Synthetic lethal strategies for the development of cancer therapeutics
NYL Ngoi, D Gallo, C Torrado, M Nardo, D Durocher, TA Yap
Nature Reviews Clinical Oncology, 1-19, 2024
12024
Abstract C163: KRAS alterations combined with TP53 mutations as novel synthetic lethal genomic lesions for PKMYT1 inhibition
ML Hyer, J Fourtounis, D Gallo, V Bhaskaran, R Stocco, R Kryczka, ...
Molecular Cancer Therapeutics 22 (12_Supplement), C163-C163, 2023
12023
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Статии 1–20