Следене
Robbie Majzner
Robbie Majzner
Dana-Farber Cancer Institute, Boston Children's Hospital, and Harvard Medical School
Потвърден имейл адрес: dfci.harvard.edu
Заглавие
Позовавания
Позовавания
Година
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ...
Nature medicine 24 (1), 20-28, 2018
14062018
Tumor antigen escape from CAR T-cell therapy
RG Majzner, CL Mackall
Cancer discovery 8 (10), 1219-1226, 2018
974*2018
c-Jun overexpression in CAR T cells induces exhaustion resistance
RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ...
Nature 576 (7786), 293-300, 2019
7222019
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
RG Majzner, S Ramakrishna, KW Yeom, S Patel, H Chinnasamy, ...
Nature 603 (7903), 934-941, 2022
6022022
CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors
RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ...
Clinical Cancer Research 25 (8), 2560-2574, 2019
5612019
Clinical lessons learned from the first leg of the CAR T cell journey
RG Majzner, CL Mackall
Nature medicine 25 (9), 1341-1355, 2019
5522019
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling
EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ...
Science 372 (6537), eaba1786, 2021
4852021
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
CW Mount, RG Majzner, S Sundaresh, EP Arnold, M Kadapakkam, ...
Nature medicine 24 (5), 572-579, 2018
4802018
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial
JY Spiegel, S Patel, L Muffly, NM Hossain, J Oak, JH Baird, MJ Frank, ...
Nature medicine 27 (8), 1419-1431, 2021
4682021
Tuning the Antigen Density Requirement for CAR T Cell Activity
RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ...
Cancer Discovery, 2020
4522020
Programming CAR-T cells to kill cancer
L Labanieh, RG Majzner, CL Mackall
Nature biomedical engineering 2 (6), 377-391, 2018
4092018
Tumor antigen and receptor densities regulate efficacy of a chimeric antigen receptor targeting anaplastic lymphoma kinase
AJ Walker, RG Majzner, L Zhang, K Wanhainen, AH Long, SM Nguyen, ...
Molecular Therapy 25 (9), 2189-2201, 2017
3742017
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
CL Flugel, RG Majzner, G Krenciute, G Dotti, SR Riddell, DL Wagner, ...
Nature Reviews Clinical Oncology 20 (1), 49-62, 2023
2522023
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ...
Nature medicine 26 (5), 712-719, 2020
2452020
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
J Theruvath, M Menard, BAH Smith, MH Linde, GL Coles, GN Dalton, ...
Nature medicine 28 (2), 333-344, 2022
1722022
Assessment of programmed death‐ligand 1 expression and tumor‐associated immune cells in pediatric cancer tissues
RG Majzner, JS Simon, JF Grosso, D Martinez, BR Pawel, M Santi, ...
Cancer 123 (19), 3807-3815, 2017
1692017
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
Y Su, JR Walker, Y Park, TP Smith, LX Liu, MP Hall, L Labanieh, R Hurst, ...
Nature Methods 17 (8), 852-860, 2020
1682020
CAR T cell therapy for neuroblastoma
RM Richards, E Sotillo, RG Majzner
Frontiers in immunology 9, 2380, 2018
1642018
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ...
Cell 185 (10), 1745-1763. e22, 2022
1582022
Co-opting signalling molecules enables logic-gated control of CAR T cells
AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ...
Nature 615 (7952), 507-516, 2023
1552023
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Статии 1–20