Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, ... Nature medicine 26 (5), 769-780, 2020 | 804 | 2020 |
Insights into the mechanism and catalysis of the native chemical ligation reaction ECB Johnson, SBH Kent Journal of the American Chemical Society 128 (20), 6640-6646, 2006 | 747 | 2006 |
PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors I Mertens, A Vandingenen, EC Johnson, OT Shafer, W Li, JS Trigg, ... Neuron 48 (2), 213-219, 2005 | 390 | 2005 |
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature neuroscience 25 (2), 213-225, 2022 | 366 | 2022 |
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, ... Science advances 6 (43), eaaz9360, 2020 | 272 | 2020 |
Identification of a circadian output circuit for rest: activity rhythms in Drosophila DJ Cavanaugh, JD Geratowski, JRA Wooltorton, JM Spaethling, ... Cell 157 (3), 689-701, 2014 | 271 | 2014 |
Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice DB Dubal, L Zhu, PE Sanchez, K Worden, L Broestl, E Johnson, K Ho, ... Journal of Neuroscience 35 (6), 2358-2371, 2015 | 228 | 2015 |
Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, ... Molecular neurodegeneration 13, 1-22, 2018 | 197 | 2018 |
A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling EC Johnson, OT Shafer, JS Trigg, J Park, DA Schooley, JA Dow, ... Journal of Experimental Biology 208 (7), 1239-1246, 2005 | 190 | 2005 |
Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-β-arrestin2 interactions EC Johnson, LM Bohn, LS Barak, RT Birse, DR Nässel, MG Caron, ... Journal of Biological Chemistry 278 (52), 52172-52178, 2003 | 137 | 2003 |
Modulation of Drosophila heartbeat by neurotransmitters E Johnson, J Ringo, H Dowse Journal of Comparative Physiology B 167, 89-97, 1997 | 131 | 1997 |
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ... The Lancet Neurology 21 (4), 329-341, 2022 | 127 | 2022 |
Multi-platform proteomic analysis of Alzheimer’s disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome EB Dammer, L Ping, DM Duong, ES Modeste, NT Seyfried, JJ Lah, ... Alzheimer's research & therapy 14 (1), 174, 2022 | 111 | 2022 |
Corazonin Neurons Function in Sexually Dimorphic Circuitry That Shape Behavioral Responses to Stress in Drosophila Y Zhao, CA Bretz, SA Hawksworth, J Hirsh, EC Johnson PLoS One 5 (2), e9141, 2010 | 111 | 2010 |
Drosophila CG8422 encodes a functional diuretic hormone receptor EC Johnson, LM Bohn, PH Taghert Journal of experimental biology 207 (5), 743-748, 2004 | 109 | 2004 |
Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila EC Johnson, N Kazgan, CA Bretz, LJ Forsberg, CE Hector, RJ Worthen, ... PloS one 5 (9), e12799, 2010 | 107 | 2010 |
Towards the total chemical synthesis of integral membrane proteins: a general method for the synthesis of hydrophobic peptide-αthioester building blocks ECB Johnson, SBH Kent Tetrahedron letters 48 (10), 1795-1799, 2007 | 105 | 2007 |
Widely distributed Drosophila G‐protein‐coupled receptor (CG7887) is activated by endogenous tachykinin‐related peptides RT Birse, EC Johnson, PH Taghert, DR Nässel Journal of neurobiology 66 (1), 33-46, 2006 | 103 | 2006 |
Genetic and Pharmacological Identification of Ion Channels Central to the Drosophila Cardiac Pacemaker E Johnson, J Ringo, N Bray, H Dowse Journal of neurogenetics 12 (1), 1-24, 1998 | 98 | 1998 |
A designer ligand specific for Kv1. 3 channels from a scorpion neurotoxin-based library Z Takacs, M Toups, A Kollewe, E Johnson, LG Cuello, G Driessens, ... Proceedings of the National Academy of Sciences 106 (52), 22211-22216, 2009 | 90 | 2009 |