Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms L Gao, M Emperle, Y Guo, SA Grimm, W Ren, S Adam, H Uryu, ZM Zhang, ... Nature communications 11 (1), 3355, 2020 | 168 | 2020 |
Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation W Ren, H Fan, SA Grimm, Y Guo, JJ Kim, J Yin, L Li, CJ Petell, XF Tan, ... Proceedings of the National Academy of Sciences 117 (31), 18439-18447, 2020 | 90 | 2020 |
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ... Nature communications 12 (1), 2490, 2021 | 84 | 2021 |
Rational Design and Optimization of m6A-RNA Demethylase FTO Inhibitors as Anticancer Agents S Huff, IR Kummetha, L Zhang, L Wang, W Bray, J Yin, V Kelley, Y Wang, ... Journal of medicinal chemistry 65 (16), 10920-10937, 2022 | 47 | 2022 |
Formation and repair of an interstrand DNA cross-link arising from a common endogenous lesion K Housh, JS Jha, Z Yang, T Haldar, KM Johnson, J Yin, Y Wang, ... Journal of the American Chemical Society 143 (37), 15344-15357, 2021 | 42 | 2021 |
m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration Y Sun, H Dai, X Dai, J Yin, Y Cui, X Liu, G Gonzalez, J Yuan, F Tang, ... Nature 623 (7987), 580-587, 2023 | 37 | 2023 |
A DNA aptamer for binding and inhibition of DNA methyltransferase 1 L Wang, JY Lee, L Gao, J Yin, Y Duan, LA Jimenez, GB Adkins, W Ren, ... Nucleic acids research 47 (22), 11527-11537, 2019 | 34 | 2019 |
A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and … R Lu, J Wang, Z Ren, J Yin, Y Wang, L Cai, GG Wang Cancer research 79 (14), 3583-3594, 2019 | 27 | 2019 |
Reconsidering the chemical nature of Strand breaks derived from abasic sites in cellular DNA: evidence for 3′-glutathionylation JS Jha, J Yin, T Haldar, Z Yang, Y Wang, KS Gates Journal of the American Chemical Society 144 (23), 10471-10482, 2022 | 18 | 2022 |
Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations L Gao, Y Guo, M Biswal, J Lu, J Yin, J Fang, X Chen, Z Shao, M Huang, ... Nature communications 13 (1), 4249, 2022 | 17 | 2022 |
Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations J Lu, Y Guo, J Yin, J Chen, Y Wang, GG Wang, J Song Nature Communications 15 (1), 3111, 2024 | 11 | 2024 |
Parallel‐reaction monitoring revealed altered expression of a number of epitranscriptomic reader, writer, and eraser proteins accompanied with colorectal cancer metastasis TF Qi, F Tang, J Yin, W Miao, Y Wang Proteomics 23 (3-4), 2200059, 2023 | 8 | 2023 |
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nat Commun 12 (1): 2490 W Ren, H Fan, SA Grimm, JJ Kim, L Li, Y Guo, CJ Petell, XF Tan, ... | 7 | 2021 |
Targeted quantitative profiling of epitranscriptomic reader, writer, and eraser proteins using stable isotope-labeled peptides TF Qi, X Liu, F Tang, J Yin, K Yu, Y Wang Analytical chemistry 94 (37), 12559-12564, 2022 | 6 | 2022 |
N-Methyl-N-nitrosourea Induced 3′-Glutathionylated DNA-Cleavage Products in Mammalian Cells J Yin, KS Gates, Y Wang Analytical chemistry 94 (45), 15595-15603, 2022 | 4 | 2022 |
Targeted proteomic approaches for proteome-wide characterizations of the AMP-binding capacities of kinases W Miao, J Yin, DF Porter, X Jiang, PA Khavari, Y Wang Journal of proteome research 21 (8), 2063-2070, 2022 | 4 | 2022 |
HMGB3 and SUB1 Bind to and Facilitate the Repair of N2-Alkylguanine Lesions in DNA T Zhao, X He, X Liang, AH Kellum Jr, F Tang, J Yin, S Guo, Y Wang, ... Journal of the American Chemical Society 146 (32), 22553-22562, 2024 | 2 | 2024 |
Temporal Profiling of Epitranscriptomic Modulators during Osteogenic Differentiation of Human Embryonic Stem Cells J Yin, TF Qi, YY Yang, M Vera-Colón, NI Zur Nieden, Y Wang Journal of proteome research 22 (7), 2179-2185, 2023 | 2 | 2023 |
Targeted profiling of Epitranscriptomic Reader, Writer, and Eraser proteins regulated by H3K36Me3 J Yin, TF Qi, L Li, Y Wang Analytical chemistry 95 (25), 9672-9679, 2023 | 1 | 2023 |
Abstract 1386 Suppress the dominant-negative effect of DNMT3A mutants in leukemogenesis J Song, J Lu, Y Guo, J Chen, J Yin, Y Wang, G Wang Journal of Biological Chemistry 300 (3), 2024 | | 2024 |