Следене
Jon M Laurent
Jon M Laurent
FutureHouse Inc.
Потвърден имейл адрес: nyumc.org
Заглавие
Позовавания
Позовавания
Година
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
AH Kachroo, JM Laurent, CM Yellman, AG Meyer, CO Wilke, EM Marcotte
Science 348 (6237), 921-925, 2015
5462015
Protein abundances are more conserved than mRNA abundances across diverse taxa
JM Laurent, C Vogel, T Kwon, SA Craig, DR Boutz, HK Huse, K Nozue, ...
Proteomics 10 (23), 4209-4212, 2010
1682010
Efforts to make and apply humanized yeast
JM Laurent, JH Young, AH Kachroo, EM Marcotte
Briefings in functional genomics 15 (2), 155-163, 2016
1342016
Single-step precision genome editing in yeast using CRISPR-Cas9
A Akhmetov, JM Laurent, J Gollihar, EC Gardner, RK Garge, AD Ellington, ...
Bio-protocol 8 (6), e2765-e2765, 2018
622018
Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte
PLoS biology 18 (5), e3000627, 2020
56*2020
Prediction of gene-phenotype associations in humans, mice, and plants using phenologs
JO Woods, UM Singh-Blom, JM Laurent, KL McGary, EM Marcotte
BMC bioinformatics 14, 1-17, 2013
552013
A versatile platform for locus-scale genome rewriting and verification
R Brosh, JM Laurent, R Ordoñez, E Huang, MS Hogan, AM Hitchcock, ...
Proceedings of the National Academy of Sciences 118 (10), e2023952118, 2021
512021
Systematic bacterialization of yeast genes identifies a near-universally swappable pathway
AH Kachroo, JM Laurent, A Akhmetov, M Szilagyi-Jones, CD McWhite, ...
Elife 6, e25093, 2017
402017
The many nuanced evolutionary consequences of duplicated genes
AI Teufel, MM Johnson, JM Laurent, AH Kachroo, EM Marcotte, CO Wilke
Molecular biology and evolution 36 (2), 304-314, 2019
342019
Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes
RK Garge, JM Laurent, AH Kachroo, EM Marcotte
Genetics 215 (4), 1153-1169, 2020
272020
Assessment of potential SARS-CoV-2 virus integration into human genome reveals no significant impact on RT-qPCR COVID-19 testing
E Briggs, W Ward, S Rey, D Law, K Nelson, M Bois, N Ostrov, HH Lee, ...
Proceedings of the National Academy of Sciences 118 (44), e2113065118, 2021
182021
Lab-bench: Measuring capabilities of language models for biology research
JM Laurent, JD Janizek, M Ruzo, MM Hinks, MJ Hammerling, ...
arXiv preprint arXiv:2407.10362, 2024
162024
Language agents achieve superhuman synthesis of scientific knowledge
MD Skarlinski, S Cox, JM Laurent, JD Braza, M Hinks, MJ Hammerling, ...
arXiv preprint arXiv:2409.13740, 2024
142024
CREEPY: CRISPR-mediated editing of synthetic episomes in yeast
Y Zhao, C Coelho, S Lauer, M Majewski, JM Laurent, R Brosh, JD Boeke
Nucleic acids research 51 (13), e72-e72, 2023
11*2023
Big DNA as a tool to dissect an age-related macular degeneration-associated haplotype
JM Laurent, X Fu, S German, MT Maurano, K Zhang, JD Boeke
Precision Clinical Medicine 2 (1), 1-7, 2019
102019
Probing the dark matter of the human genome with big DNA
JM Laurent, S Pinglay, L Mitchell, R Brosh
The Biochemist 41 (3), 46-48, 2019
52019
Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast
M Abdullah, BM Greco, JM Laurent, RK Garge, DR Boutz, M Vandeloo, ...
Cell Reports Methods 3 (5), 2023
42023
Wikicrow: Automating synthesis of human scientific knowledge
S Cox, M Hammerling, J Lála, J Laurent, S Rodriques, M Rubashkin, ...
Future House, 2023
32023
Development and scaling of a sequencing pipeline for genomic surveillance of SARS-CoV-2 in New York City
MJ Hammerling, SC Kang, W Ward, IF Escapa, P Bugga, C Del Castillo, ...
medRxiv, 2022.05. 25.22273991, 2022
32022
Aviary: training language agents on challenging scientific tasks
S Narayanan, JD Braza, RR Griffiths, M Ponnapati, A Bou, J Laurent, ...
arXiv preprint arXiv:2412.21154, 2024
12024
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